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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New Caltech study shows how chaperones protect ribosomal proteins

For proteins, this would be the equivalent of the red-carpet treatment: each protein belonging to the complex machinery of ribosomes -- components of the cell that produce proteins -- has its own chaperone to guide it to the right place at the right time and protect it from harm.

3 Feb 2017

Thirdhand smoke exposure leads to biological effects on weight and cell development

The sticky residue left behind by tobacco smoke can do worse damage than stinking up furniture and discoloring walls.

3 Feb 2017

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

3 Feb 2017

Single Molecule Detection of Proteins in Single Cells

We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my laboratory at the time.

From Pittcon 3 Feb 2017

GIANT study uncovers new, rare DNA changes that affect human height

In the largest, deepest search to date, the international Genetic Investigation of Anthropometric Traits Consortium has uncovered 83 new DNA changes that affect human height.

3 Feb 2017

Illumina debuts new software to optimize data analysis for noninvasive prenatal testing

Illumina, Inc. today announced that it has declared conformity with the requirements of the IVD Directive and has applied the CE mark to an expanded VeriSeq NIPT Analysis Software for clinical laboratories in the European Union (EU).

From Illumina, Inc. 3 Feb 2017

Research unravels molecular mechanisms of antisense oligonucleotides

Stanley T. Crooke, MD, PhD, CEO of Ionis Pharmaceuticals and recipient of the 2016 Lifetime Achievement Award from the Oligonucleotide Therapeutic Society presents a detailed look at the mechanisms that underlie antisense drug activity in the article entitled "Molecular Mechanisms of Antisense Oligonucleotides," published in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

2 Feb 2017

Study finds impaired secretion of stress hormone in healthy Indigenous young adults

James Cook University scientists have made a disturbing finding about some young Indigenous people's biological reaction to stress, but one that could help close the health gap for indigenous people.

2 Feb 2017

Study looking for toxicity markers in smokers who replace tobacco for e-cigarettes seeks volunteers

The first study to closely follow toxicity markers in smokers who replace tobacco for e-cigarettes is seeking volunteers.

2 Feb 2017

IDT offers cost-effective and most complete spectrum of CRISPR genome editing systems

Reflecting its drive to provide innovative solutions to the genomics community, Integrated DNA Technologies (IDT) is the first genomics company to develop and bring to market a complete ribonucleoprotein-based Cpf1 CRISPR system.

2 Feb 2017

Blood test that spots tumor DNA predicts survival of advanced breast cancer patients

Results of a multicenter study of 129 women with advanced breast cancer show that a blood test that spots cancer-linked DNA correctly predicted that most of those patients with higher levels of the tumor markers died significantly earlier than those with lower levels.

2 Feb 2017

SLU scientists receive $416,000 NIH grant to advance research on hepatitis B cure

With a $416,000 grant from the National Institutes of Health (NIH), SLU scientists will continue work to cure hepatitis B, building on significant findings published in two recent papers.

1 Feb 2017

Study finds new links between human genome and inflammation tracers

Researchers from the Research Centre of Applied and Preventive Cardiovascular Medicine at the University of Turku, Finland, have studied over ten million DNA variations and found new links between the human genome and inflammation tracers.

1 Feb 2017

Defects in key gene spur breast and ovarian cancer growth, study shows

Defects in a key gene - long thought to drive cancer by turning off the protection afforded by the well-known BRCA genes - spur cancer growth on their own, according to a study led by researchers from NYU Langone Medical Center.

31 Jan 2017

Spanish scientists introduce new UVA and UVB filters based on natural sunscreen substances

The ideal sunscreen should block UVB and UVA radiation while being safe and stable. In the journal Angewandte Chemie, Spanish scientists have introduced a new family of UVA and UVB filters based on natural sunscreen substances found in algae and cyanobacteria. They are highly stable and enhance the effectivity of commercial sunscreens.

31 Jan 2017

NIH awards grant to UND study that focuses on early formation of cancer-causing viruses

The list is long. From the common cold and influenza to HIV and measles, and from Zika to some cancers, all are caused by viruses — tiny packages of either DNA or RNA that wear a protein coat.

31 Jan 2017

TSRI study offers first look at early stages of brain development in patients with Fragile X syndrome

A new study led by scientists at The Scripps Research Institute is giving researchers a first look at the early stages of brain development in patients with Fragile X syndrome, a disorder that causes mild to severe intellectual disability and is the most common genetic cause of autism spectrum disorder.

31 Jan 2017

Jefferson researchers reveal new insight into two states of viral protein

To generate swarms of new viral particles, a virus hijacks a cell into producing masses of self-assembling cages that are then loaded with the genetic blueprint for the next infection.

31 Jan 2017

JAX researchers unravel mechanism that enables cancer cells to survive and divide

Some cancer cells have a trick up their sleeve to avoid cell death: boosting maintenance of telomeres, the protective "end caps" on chromosomes, and a research team led by Jackson Laboratory Professor Roel Verhaak reports in Nature Genetics on a newly discovered telomere maintenance mechanism.

31 Jan 2017

Researchers develop online resource to gather, organize research information on cancer mutations

The body of knowledge on cancer genomics is massive and ever-expanding. But this wealth of potentially critical information is far less likely to be of help to patients if it is inaccessible to the doctors who treat them.

31 Jan 2017

DNA News and Research

Further Reading

New Caltech study shows how chaperones protect ribosomal proteins

Thirdhand smoke exposure leads to biological effects on weight and cell development

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

Single Molecule Detection of Proteins in Single Cells

GIANT study uncovers new, rare DNA changes that affect human height

Illumina debuts new software to optimize data analysis for noninvasive prenatal testing

Research unravels molecular mechanisms of antisense oligonucleotides

Study finds impaired secretion of stress hormone in healthy Indigenous young adults

Study looking for toxicity markers in smokers who replace tobacco for e-cigarettes seeks volunteers

IDT offers cost-effective and most complete spectrum of CRISPR genome editing systems

Blood test that spots tumor DNA predicts survival of advanced breast cancer patients

SLU scientists receive $416,000 NIH grant to advance research on hepatitis B cure

Study finds new links between human genome and inflammation tracers

Defects in key gene spur breast and ovarian cancer growth, study shows

Spanish scientists introduce new UVA and UVB filters based on natural sunscreen substances

NIH awards grant to UND study that focuses on early formation of cancer-causing viruses

TSRI study offers first look at early stages of brain development in patients with Fragile X syndrome

Jefferson researchers reveal new insight into two states of viral protein

JAX researchers unravel mechanism that enables cancer cells to survive and divide

Researchers develop online resource to gather, organize research information on cancer mutations

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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