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Study determines the diagnostic utility of liver stiffness measurement

Even after chronic hepatitis C has been cured, portal hypertension remains the major factor driving the development of complications in advanced liver disease. In cooperation with researchers from Spain, a research team led by Georg Semmler and Mattias Mandorfer from the Division of Gastroenterology and Hepatology at MedUni Vienna's Department of Medicine III showed that the non-invasive tests explored in their earlier studies accurately estimate the probability of sequelae.

3 Nov 2022

Experts estimate the prevalence of breast cancer survivors in Canada

It was the information she couldn't find that led Amy Kirkham, an assistant professor in the University of Toronto's Faculty of Kinesiology & Physical Education (KPE), to her latest discovery.

3 Nov 2022

New insights into the dynamic inner world of the human immune system

As researchers glean new insights into the dynamic inner world of the human immune system, it has become increasingly clear that mitochondria are critical regulators of how our bodies respond to disease.

3 Nov 2022

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led by pediatric oncologists at Roswell Park Comprehensive Cancer Center, Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University. By combining the targeted antibody-drug conjugate (ADC) brentuximab vedotin (BV) with the standard chemotherapy regimen, children were 10% less likely to relapse.

2 Nov 2022

Many middle-aged adults unlikely to participate in dementia prevention clinical trials

Right now, drug companies and university-based teams are working urgently to find and test new medications that could prevent or slow the decline of brain function in older adults.

2 Nov 2022

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell's Ithaca campus.

2 Nov 2022

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Innate lymphoid cells are a recently discovered family of white blood cells that reside in the skin, gastrointestinal tract, airways and other barrier tissues of the body.

2 Nov 2022

Ohio State researchers enter federal cooperative agreement to develop radiation biodosimetry solutions

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) have entered a federal cooperative agreement, valued up to $9.42 million, that will help them further develop Ohio State's biodosimetry technology to discover noninvasive biomarkers for radiation exposure – work that will have national security applications.

2 Nov 2022

Research agenda provides a roadmap for eliminating racism in emergency medicine

In 2021, the Society for Academic Emergency Medicine (SAEM) held a consensus conference, From Bedside to Policy: Advancing Social Emergency Medicine and Population Health, which included identifying priority areas for future research and implementation science related to race, racism and antiracism in emergency medicine (EM).

2 Nov 2022

Study uncovers a control hub for skin inflammation

Inflammatory reactions in the skin can reduce damage from UV radiation or infections, but can also result in painful symptoms such as sunburn.

2 Nov 2022

Researchers corroborate the importance of exercise for cognitive function

Accumulating evidence finds that exercise can improve brain function and delay or prevent the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

2 Nov 2022

Contrastive learning model can detect lung damage in long-COVID patients

For patients dealing with lingering respiratory symptoms from the novel coronavirus, a chest X-ray can reveal only so much.

2 Nov 2022

Researchers identify new therapeutic approach against treatment-resistant prostate cancer

Investigators from Cedars-Sinai Cancer have identified an investigational therapeutic approach that could be effective against treatment-resistant prostate cancer. Results of their Phase II clinical trial, published in the peer-reviewed journal Molecular Therapy, have led to a larger, multicenter trial that will soon be underway.

2 Nov 2022

UC researchers receive NIH grant to study how alcohol, fentanyl affect HIV medications

The United States has set a goal of reducing the number of new HIV infections by 75% by 2025 and by at least 90% by 2030, mirroring the United Nations' initiative to end the AIDS epidemic as a global health threat by 2030.

2 Nov 2022

Personalized approach to kidney disease screening for T1D patients could enable earlier disease detection

Taking a personalized approach to kidney disease screening for people with type 1 diabetes (T1D) may reduce the time that chronic kidney disease goes undetected, according to a new analysis performed by the Epidemiology of Diabetes Interventions and Complications study group, which is funded by the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health.

2 Nov 2022

The use of wearable health devices by cardiovascular disorder patients and those at an increased risk of cardiovascular disorders in the US

Researchers evaluated the usage of WHDs (wearable health devices) by cardiovascular (CVS) disorder patients and those at an increased risk of CVS disorders in the United States (US).

2 Nov 2022

Molecular drug transporters could improve treatment of cancers and other diseases

A team of Canadian researchers from Université de Montréal has designed and validated a new class of drug transporters made of DNA that are 20,000 times smaller than a human hair and that could improve how cancers and other diseases are treated.

2 Nov 2022

Memory: a revolutionary treatment for mental health disorders and neurodegeneration?

In this interview, we speak to Dr. Steve Ramirez about his latest neuroscience research that investigated the power of our memories.

2 Nov 2022

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

A new study aimed to analyze the molecular interactions between the hCypA protein and the SARS-CoV-2 variants to determine the impact of variants on the blocking and binding potential of the hCypA–S protein complex with the ACE2 receptor.

2 Nov 2022

Hurricane Ian’s deadly impact on Florida seniors exposes need for new preparation strategies

All kinds of natural disasters — hurricanes, tornadoes, floods, wildfires, dangerous heat waves — pose substantial risks to older adults. Yet, not enough seniors prepare for these events in advance, and efforts to encourage them to do so have been largely unsuccessful.

2 Nov 2022

Medicine News and Research

Study determines the diagnostic utility of liver stiffness measurement

Experts estimate the prevalence of breast cancer survivors in Canada

New insights into the dynamic inner world of the human immune system

Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

Many middle-aged adults unlikely to participate in dementia prevention clinical trials

Dietary inulin fiber can promote allergy-related type of inflammation in the gut and lungs

Study provides new set of targets for drug therapies to combat chronic inflammatory diseases

Ohio State researchers enter federal cooperative agreement to develop radiation biodosimetry solutions

Research agenda provides a roadmap for eliminating racism in emergency medicine

Study uncovers a control hub for skin inflammation

Researchers corroborate the importance of exercise for cognitive function

Contrastive learning model can detect lung damage in long-COVID patients

Researchers identify new therapeutic approach against treatment-resistant prostate cancer

UC researchers receive NIH grant to study how alcohol, fentanyl affect HIV medications

Personalized approach to kidney disease screening for T1D patients could enable earlier disease detection

The use of wearable health devices by cardiovascular disorder patients and those at an increased risk of cardiovascular disorders in the US

Molecular drug transporters could improve treatment of cancers and other diseases

Memory: a revolutionary treatment for mental health disorders and neurodegeneration?

What is the role of cyclophilin-A in alleviating SARS-CoV-2 infections?

Hurricane Ian’s deadly impact on Florida seniors exposes need for new preparation strategies

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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