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FISH assay identifies only few lung cancer patients who could benefit from crizotinib

Break apart a couple worm-like chromosomes and they may reconnect with mismatched tips and tails - such is the case of the EML4-ALK fusion gene that creates 2-7 percent of lung cancers. Almost exactly a year ago, the FDA approved the drug crizotinib to treat these ALK+ lung cancer patients, who were likely never smokers. Informed doctors use the test called a FISH assay to check for the EML4-ALK fusion gene, and then if the test is positive, ALK+ patients benefit greatly from crizotinib.

29 Aug 2012

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Pulmatrix, Inc., a clinical stage biotechnology company creating novel inhaled therapeutics, announced today that three posters on its lead iCALM therapeutic, the first treatment developed utilizing its iSPERSE inhaled drug platform, will be presented at the European Respiratory Society (ERS) Annual Congress taking place September 1-5, 2012, in Vienna, Austria.

28 Aug 2012

Copeptin estimates prognosis in patients with heart failure

Copeptin predicts prognosis in patients with heart failure, according to research presented at the ESC Congress today, August 25, by Professor Stefan St-rk from Germany.

28 Aug 2012

ICU misdiagnosis alarmingly common in the acute care setting

Each year as many as 40,500 critically ill U.S. hospital patients die with an unknown medical condition that may have caused or contributed to their death, Johns Hopkins patient safety experts report in a recent study.

28 Aug 2012

More than 40 plant-based compounds can turn on genes that slow the spread of cancer

More than 40 plant-based compounds can turn on genes that slow the spread of cancer, according to a first-of-its-kind study by a Washington State University researcher.

28 Aug 2012

Spinal cord stimulation could become novel treatment option for heart failure

Spinal cord stimulation improves heart function and could become a novel treatment option for heart failure, according to research presented at the ESC Congress 2012 today, August 25, by Professor Hung-Fat Tse from Hong Kong.

28 Aug 2012

Allegro Diagnostics announces results from BronchoGen genomic test trial on lung cancer

Allegro Diagnostics today announced that results from its AEGIS (Airway Epithelium Gene Expression In the Diagnosis of Lung Cancer) clinical trials, to determine the accuracy of the BronchoGen genomic test, have been accepted for an oral presentation during the late-breaking abstract session at CHEST 2012 on Tuesday, October 23, 2012 at 4:30 p.m. The abstract will also be published in a supplement of the October 2012 issue of CHEST.

28 Aug 2012

Nearly 7% of urologic MDCT scans for hematuria result in incidental findings

A new study from Rhode Island Hospital reports that nearly seven percent of urologic multi-detector computed tomography (MDCT) scans for hematuria result in incidental findings that may be clinically important for the patient. The study is published in the American Journal of Roentgenology.

28 Aug 2012

Oral FluCide drug candidates effective in reducing lung viral load: NanoViricides

NanoViricides, Inc. announced today that anti-influenza drug candidates under its FluCide program, when given orally, were nearly as effective as when administered as IV injections in terms of reduction in lung viral load.

27 Aug 2012

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

New data to be presented at the Annual Congress of the European Respiratory Society (ERS 2012), in Vienna, Austria, will shed light on the current and potential future role of tiotropium, the first once-daily long-acting inhaled anticholinergic for patients with Chronic Obstructive Pulmonary Disease (COPD).

27 Aug 2012

MedQIA develops new software that forms the basis of Imaging Biomarker Information System

MedQIA has developed a software toolkit of image analysis routines that forms the basis of an Imaging Biomarker Information System (IBIS).

27 Aug 2012

International Association for the Study of Lung Cancer receives ACCME accreditation

The International Association for the Study of Lung Cancer (IASLC) has been awarded Provisional Accreditation as a Continuing Medical Education (CME) provider by the Accreditation Council for Continuing Medical Education (ACCME).

26 Aug 2012

Electronic cigarettes far less harmful and may be beneficial to health

Smoking is the most preventable risk factor for cardiac and lung disease and is expected to cause 1 billion deaths during the 21st century. Electronic cigarettes have been marketed in recent years as a safer habit for smokers, with several millions of people already using them worldwide.

26 Aug 2012

Study addresses important early risk factors of cardiovascular health in adolescents

Early exposure to tobacco smoke is associated with various adverse health outcomes in children and adolescents, including low birth weight and impaired lung growth and function.

26 Aug 2012

State Senator honors UCLA lung transplant doctors during special ceremony

Dr. Abbas Ardehali, professor of cardiothoracic surgery and director of the UCLA Heart and Lung Transplant program, and Dr. David Ross, professor of pulmonology and medical director of the UCLA Lung Transplant program, were honored by State Senator Sharon Runner (R-Antelope Valley) during a special ceremony at the State Senate Chamber in Sacramento on Aug. 21.

24 Aug 2012

Dartmouth’s professor shares news of DAR-901 TB vaccine development

Tuberculosis (TB) is second only to HIV/AIDS as the greatest killer worldwide attributable to a single infectious agent, according to the World Health Organization (WHO). With 8.8 million cases in 2010 and 95 percent of TB deaths occurring in low- and middle-income countries, the disease continues to be a major public health problem in the developing world. In a July address to the International Union Against Tuberculosis and Lung Disease, Dartmouth's C. Fordham (Ford) von Reyn shared news of a promising vaccine in the works.

24 Aug 2012

GlcNAc plays a key role in keeping cancerous monsters ‘fed’

Behaving something like ravenous monsters, tumors need plentiful supplies of cellular building blocks such as amino acids and nucleotides in order to keep growing at a rapid pace and survive under harsh conditions. How such tumors meet these burgeoning demands has not been fully understood.

24 Aug 2012

Lungs News and Research

FISH assay identifies only few lung cancer patients who could benefit from crizotinib

Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress

Copeptin estimates prognosis in patients with heart failure

ICU misdiagnosis alarmingly common in the acute care setting

More than 40 plant-based compounds can turn on genes that slow the spread of cancer

Spinal cord stimulation could become novel treatment option for heart failure

Allegro Diagnostics announces results from BronchoGen genomic test trial on lung cancer

Nearly 7% of urologic MDCT scans for hematuria result in incidental findings

Oral FluCide drug candidates effective in reducing lung viral load: NanoViricides

New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD

MedQIA develops new software that forms the basis of Imaging Biomarker Information System

International Association for the Study of Lung Cancer receives ACCME accreditation

Electronic cigarettes far less harmful and may be beneficial to health

Study addresses important early risk factors of cardiovascular health in adolescents

State Senator honors UCLA lung transplant doctors during special ceremony

Dartmouth’s professor shares news of DAR-901 TB vaccine development

GlcNAc plays a key role in keeping cancerous monsters ‘fed’

Results from Biodesix VeriStrat phase II advanced lung cancer trials

Study helps explain how human airways clear sticky mucus out of the lungs

Influenza virus can change microRNA expression to control immune responses in human lung cells

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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