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High-traffic 'hub neurons' may play role in understanding brain health

Just as most of the world's air travel passes through a few major hubs, the majority of information in the brain flows through similarly well-traveled routes, Indiana University scientists have found.

21 Jan 2016

New imaging test detects prostate cancer much better than any other tests in use today

Researchers at Thomas Jefferson University have found the method they developed to image the prostate appears to be much better at detecting prostate cancer than any other test — radiographical, biopsy or blood — in use today.

20 Jan 2016

$Novel technique helps identify diabetic patients at risk of bone fractures$

Novel technique helps identify diabetic patients at risk of bone fractures

A Southampton study using high resolution imaging to create a "virtual bone biopsy" has shed new light on why people with type 2 diabetes are at risk of bone fractures.

20 Jan 2016

Researchers reconstruct 3D images of protein structures that link heart muscle cells in working groups

Diseased hearts may be thrown out of rhythm by structural differences -- now visible for the first time -- in protein groups that connect heart muscle cells, according to the authors of a study to be published in the journal Nature Communications online Jan. 20.

20 Jan 2016

Amorphous iron nanoparticles have potential to kill tumor cells

Amorphous iron nanoparticles have a specific toxicity in tumor cells. In the journal Angewandte Chemie, Chinese scientists describe their design and synthesis of a special amorphous state of nanoparticulate iron, which can locally release reactive iron species in the acidic and hydrogen peroxide rich environment of cancer cells, providing new possibilities for theranostics and chemodynamic therapies.

20 Jan 2016

Pioneer calls on electrophysiologists to reexamine substrate mapping for deadly heart arrhythmia

A pioneer in developing life-saving therapies for a deadly heart arrhythmia has called on electrophysiologists to reexamine a widely used technique to guide the treatment of the faulty electrical impulses responsible for these abnormal heartbeats.

20 Jan 2016

New study sheds light on possible role of ion channel in the immune system

Many cells have microscopic gates, called ion channels, which open to allow the flow of ions across the cell membrane. Thanks to these gates, cells can detect stimuli such as heat, pain, pressure and even spicy food.

20 Jan 2016

UCSF-led study shows increase in use of CT scans in patients with non-serious injuries

Twice as many patients with non-serious injuries, such as fractures or neck strain, are undergoing CT scans in emergency departments at California hospitals, according to a UCSF-led study, which tracked the use of the imaging from 2005 to 2013.

20 Jan 2016

Optical technologies could lead to novel treatments for neurological diseases

Optical technologies previously used to look at the stars in the sky will be miniaturized to look inside the brain, and could lead to new treatments for neurological diseases.

20 Jan 2016

New method could improve accurate diagnosis of ovarian cancer before surgery

In a landmark study, investigators from Europe propose a new and simple method to assess the risk of malignancy of women with an adnexal mass. The method identified between 89-99% of patients with ovarian cancer using the results of ultrasound examination, which can be obtained in referral and non-referral centers.

20 Jan 2016

Interictal discharges have neuropsychological effects in rolandic epilepsy

Centrotemporal spikes experienced between seizures by children with rolandic epilepsy may disrupt functional brain networks and contribute to language, behaviour and cognitive problems, research suggests.

19 Jan 2016

Compensatory neural connections stave off bipolar disorder onset

Patients at high genetic risk of bipolar disorder may be able to avert onset of the condition due to natural adaptive neuroplasticity that allows the brain to compensate for underlying network dysfunction associated with the condition, researchers report.

19 Jan 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

New clinical imaging method may enable doctors to tackle lung infections

A new clinical imaging method developed in collaboration with a University of Exeter academic may enable doctors to tackle one of the main killers of patients with weakened immune systems sooner and more effectively.

19 Jan 2016

New sites opened across the South West for Alzheimer’s disease clinical trial

People with Alzheimer’s disease are helping with a ground-breaking government-funded trial but with new sites recently opened in the South West more people are being asked to take part in the study led by academics from the Universities of Bristol, Cambridge, Queen’s University Belfast and University College London, and hosted by North Bristol NHS Trust.

19 Jan 2016

Mount Sinai Heart starts TANSNIP-PESA study to determine how workplace-based lifestyle intervention reduces CV risk

World-renowned cardiologist Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Physician-in-Chief of The Mount Sinai Hospital, is undertaking a three-year study, known as the TANSNIP-PESA study, to determine whether a workplace-based lifestyle intervention, accompanied by imaging data, will lead to a reduction in the prevalence of cardiovascular (CV) disease risk factors related to lifestyle.

19 Jan 2016

Patients enrolled in high-deductible health insurance plans use fewer diagnostic tests

Patients enrolled in high-deductible health insurance plans have lower rates of use and lower costs for imaging tests, suggests a study in the February issue of Medical Care.

18 Jan 2016

Taking up new mental challenges may help maintain cognitive vitality

One of the greatest challenges associated with the growing numbers of aged adults is how to maintain a healthy aging mind. Taking up a new mental challenge such as digital photography or quilting may help maintain cognitive vitality, say researchers reporting in Restorative Neurology and Neuroscience.

18 Jan 2016

New study shows neurocognitive benefits of stand-height desks in classrooms

Do students think best when on their feet? A new study by the Texas A&M Health Science Center School of Public Health indicates they do.

18 Jan 2016

Graph theoretical analysis may help predict recovery of motor function after stroke

Graph theoretical analysis is proving to be helpful in understanding complex networks in the brain. Investigators in the Republic of Korea used a graph theoretical approach in examining the changes in the configuration of the two hemispheres of the brain in 12 patients after stroke.

18 Jan 2016