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Understanding the cause for suboptimal germinal center response in aged mice

Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.

22 May 2023

The State of Tech Bio: Survey finds majority of biodevelopers write code and use machine learning; protein engineering is a top priority

Cradle, the platform that helps scientists to design and program proteins, today published the findings of its first BioDeveloper survey, exploring the methods and priorities of biodevelopers to build a picture of trends within the synthetic biology sector.

From Cradle Bio B.V. 22 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Research paper discusses the differences in microbiota between high and low IgA subjects after the second dose of the COVID-19 vaccine. The study found that certain microbial features in breast milk can predict levels of anti-SARS-CoV-2 antibodies in breast milk one week post-second dose.

21 May 2023

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Researchers demonstrated the production of cross-clade neutralizing antibodies in response to EV-D68.

19 May 2023

Mouse study offers clues to developing an effective vaccine for Klebsiella bacteria

A mouse study at Washington University School of Medicine in St. Louis points to data that could be key to developing an effective vaccine for the bacterium Klebsiella pneumoniae.

18 May 2023

Research paves the way to safer, more effective treatment for children with aggressive blood cancers

Australian nanomedicine researchers have come up with a new approach to solving a decades-old clinical problem: getting treatment drugs to act selectively on cancer cells in the body.

18 May 2023

Investigating the changes in severity and epidemiology of respiratory syncytial virus infections among children

Shifting Epidemiology and Severity of Respiratory Syncytial Virus in Children During the COVID-19 Pandemic.

18 May 2023

Using synthetic peptides for inflammatory disease diagnosis

Scientists have developed a peptide that binds to the protein calprotectin, a marker of major inflammatory disorders, and shown that it is suitable for diagnostic tests.

17 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

"Smart" sutures can detect inflammation and release drugs

Inspired by sutures developed thousands of years ago, MIT engineers have designed "smart" sutures that can not only hold tissue in place, but also detect inflammation and release drugs.

16 May 2023

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

Patients with cancer whose immune systems are being supported or rebuilt by bone marrow transplantation should begin receiving vaccines for protection against SARS-CoV-2 three months post-transplant, according to a large, prospective, observational study led collaboratively by the Center for International Blood and Marrow Transplant Research, the Blood & Marrow Transplant Clinical Trials Network and Fred Hutchinson Cancer Center.

16 May 2023

PhenomeX Launches Beacon Select™ Optofluidic System with Opto® B Discovery Workflows

Affordable two-chip Beacon Select system to broaden customer access to innovative high throughput, function-first antibody discovery capabilities.

From Bruker Cellular Analysis 16 May 2023

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

Through a recent platform demonstration project, LabGenius’ machine learning-driven lead optimisation capability delivered dozens of novel T-cell engagers with best-in-class killing selectivity.

From LabGenius 16 May 2023

Insights from blood donors: Serosurveillance reveals population insights for targeted health interventions

Research highlights the effectiveness of serosurveillance in monitoring SARS-CoV-2 exposure within a population. It emphasizes the importance of considering demographic variations in antibody prevalence to inform targeted public health strategies.

16 May 2023

Obesity undermines COVID-19 vaccines

Researchers examine the impact of obesity on COVID-19 outcomes and the effectiveness of vaccines in individuals with obesity. Using data from Scotland, the study explores the relationship between body mass index (BMI) and hospitalization/mortality due to COVID-19.

15 May 2023

Study indicates that the Omicron wave and the rollout of vaccines led to almost 100% seropositivity and boosted anti-spike IgG titers in children and adolescents

Researchers discussed the presence of persistent humoral immunity among children and adolescents during COVID-19.

15 May 2023

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Scientists explore the use of deep generative models in producing complete instances of as-yet undiscovered SARS-CoV2 Spike protein sequences. The resulting models substantially outperform a state-of-the-art generative model for protein sequences finetuned on SARS-CoV2 data.

14 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

Researchers longitudinally isolated immensely potent monoclonal antibodies from macaques vaccinated with COVID-19.

12 May 2023

Antibodies News and Research

Understanding the cause for suboptimal germinal center response in aged mice

The State of Tech Bio: Survey finds majority of biodevelopers write code and use machine learning; protein engineering is a top priority

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Mouse study offers clues to developing an effective vaccine for Klebsiella bacteria

Research paves the way to safer, more effective treatment for children with aggressive blood cancers

Investigating the changes in severity and epidemiology of respiratory syncytial virus infections among children

Using synthetic peptides for inflammatory disease diagnosis

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

"Smart" sutures can detect inflammation and release drugs

Cancer patients can initiate SARS-CoV-2 vaccination three months after bone marrow transplant

PhenomeX Launches Beacon Select™ Optofluidic System with Opto® B Discovery Workflows

LabGenius Debuts T-cell Engager Optimisation Capability That Yields Molecules with >400-fold Tumour Killing Selectivity Versus Clinical Benchmark

Insights from blood donors: Serosurveillance reveals population insights for targeted health interventions

Obesity undermines COVID-19 vaccines

Study indicates that the Omicron wave and the rollout of vaccines led to almost 100% seropositivity and boosted anti-spike IgG titers in children and adolescents

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Using an intracellular toolkit to map organelle bio-geography in stem cells

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

Immunology eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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