High Cholesterol News and Research

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Amgen reports that Phase 3 DESCARTES study for high cholesterol meets primary endpoint

Amgen today announced that the Phase 3 DESCARTES (Durable Effect of PCSK9 Antibody CompARed wiTh PlacEbo Study) study evaluating the long-term 52-week safety and efficacy of evolocumab for the treatment of high cholesterol met its primary endpoint of percent reduction from baseline in low-density lipoprotein cholesterol (LDL-C) at week 52.

20 Dec 2013

Research suggests connection between adult's height and prevalence of CAC

Minneapolis Heart Institute Foundation research cardiologist Dr. Michael Miedema is the lead author of a paper published by Circulation - Cardiovascular Imaging, a journal of the American Heart Association, that suggests a connection between an adult's height and the prevalence of coronary artery calcium (CAC), a direct marker of plaque in the arteries that feed the heart.

13 Dec 2013

High cholesterol fuels growth and spread of breast Cancer

Researchers at Duke Medicine conclude that high cholesterol may make breast cancer worse when they found that a byproduct of cholesterol functions like the hormone estrogen, leading to increases in the growth and spread of breast cancer. Studies have previously shown the link between obesity and breast cancer, but the exact cause of the increased risk had not been identified.

11 Dec 2013

Researchers identify central switch by which HDL controls inflammatory response

High-density lipoprotein, known colloquially as "good cholesterol", protects against dangerous deposits in the arteries. An important function of HDL is its anti-inflammatory properties. An international research team at the Institute of Innate Immunity at the University Hospital of Bonn and the LIMES Institute at the University of Bonn has identified a central switch by which HDL controls the inflammatory response. The results are presented in the current issue of "Nature Immunology".

9 Dec 2013

Long-term untreated PTSD symptoms may increase risk of cardiovascular health

There is growing concern that long-term untreated posttraumatic stress disorder (PTSD) symptoms may increase the risk of developing a number of medical problems, particularly compromised cardiovascular health.

2 Dec 2013

Elevated cholesterol is associated with breast cancer risk

A byproduct of cholesterol functions like the hormone estrogen to fuel the growth and spread of the most common types of breast cancers, researchers at the Duke Cancer Institute report.

29 Nov 2013

Walk-in clinics staffed by nurses can reduce health care costs, says URI professor

People who don't have health insurance are often forced to seek treatment at hospital emergency rooms for colds, body aches and other routine illnesses. Those visits cost patients, hospitals and taxpayers millions of dollars every year.

28 Nov 2013

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer. However, the particles have to be injected into patients, which has limited their usefulness so far.

27 Nov 2013

Brown fat stem cells may lead to new treatments for heart and endocrine disorders

Obesity and diabetes have become a global epidemic leading to severe cardiovascular disease. Researchers at the University of Utah believe their recent identification of brown fat stem cells in adult humans may lead to new treatments for heart and endocrine disorders, according to a new study published in the peer-reviewed journal Stem Cells.

22 Nov 2013

Doctor-patient communication critical for success of patient-centered medical homes

A new trend in American health care is the patient-centered medical home. The approach revolves around a team of medical and health professionals who, working together, treat an individual, led by a primary-care physician who orchestrates the whole effort. The goal is the team knows everything about the patient, no matter how disparate the symptoms—from the earache last night to the long history of high cholesterol—and works together to treat the individual in a holistic way.

20 Nov 2013

Patients at highest risk for suffering full-blown ischemic attack less likely to receive optimal care

Among thousands of hospital patients treated for a "mini stroke," those who were at highest risk for suffering a full-blown ischemic attack were less likely to received optimal care, according to a study led by researchers at Duke Medicine.

20 Nov 2013

Chronic diseases account for increasing proportion of GPs' workload

GPs in Australia are working three hours less per week in direct clinical care, however they are dealing with more health problems per visit, research led by the University of Sydney shows.

19 Nov 2013

Measuring BMI can help predict diabetic patient's risk for heart disease

Researchers from the Intermountain Medical Center Heart Institute, in collaboration with researchers from Johns Hopkins University and the National Institutes of Health, have discovered a simple way to further predict a diabetic patient's risk for heart disease: by measuring their body mass index or BMI.

17 Nov 2013

Study finds consistent sleep pattern can reduce risk of illness among adolescents

Newly released findings from Bradley Hospital published in the Journal of Sleep Research have found that acute illnesses, such as colds, flu, and gastroenteritis were more common among healthy adolescents who got less sleep at night. Additionally, the regularity of teens' sleep schedules was found to impact their health.

15 Nov 2013

HIVMA's updated HIV care guidelines show doctors should focus on common health conditions

The HIV Medicine Association of the Infectious Diseases Society of America has updated its HIV care guidelines to reflect the fact that people with HIV are now living normal life spans, and their physicians need to focus on preventive care, including screening for high cholesterol, diabetes and osteoporosis.

15 Nov 2013

Few newly diagnosed high-cholesterol patients get screened for thyroid dysfunction: Study

Despite current guidelines that recommend newly diagnosed high-cholesterol patients have a TSH blood test done to make sure they do not have hypothyroidism, researchers from Boston University School of Medicine and Boston Medical Center have found that only about half of these patients were screened for thyroid dysfunction.

15 Nov 2013

Results announced for Phase 3B/4 study of RAPAMUNE in kidney transplant patients

Pfizer Inc. (NYSE:PFE) announced today top-line results from a Phase 3B/4 study of RAPAMUNE® (sirolimus) evaluating kidney transplant patients who transitioned from tacrolimus-based therapy (TAC) to RAPAMUNE® 3 to 5 months after transplant.

12 Nov 2013

Obesity, overweight are risk factors for MI and IHD regardless of metabolic syndrome

Being overweight or obese are risk factors for myocardial infarction (heart attack) and ischemic heart disease (IHD) regardless of whether individuals also have the cluster of cardiovascular risk factors known as metabolic syndrome, which includes high blood pressure, high cholesterol and high blood sugar, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

12 Nov 2013

Atrial fibrillation doubles risk of heart attack in women and African Americans

Doctors have known for years that atrial fibrillation, or irregular heartbeat, increases the risk for stroke, but now researchers at Wake Forest Baptist Medical Center have shown that it also increases the risk for heart attack. In fact, for women and African Americans, it more than doubles the risk.

5 Nov 2013

Most severely obese teenagers who underwent bariatric WLS experience no major complications

Most severely obese teenagers who underwent bariatric weight-loss surgery (WLS) experienced no major complications, according to a study published by JAMA Pediatrics, a JAMA Network publication.

5 Nov 2013

High Cholesterol News and Research

Amgen reports that Phase 3 DESCARTES study for high cholesterol meets primary endpoint

Research suggests connection between adult's height and prevalence of CAC

High cholesterol fuels growth and spread of breast Cancer

Researchers identify central switch by which HDL controls inflammatory response

Long-term untreated PTSD symptoms may increase risk of cardiovascular health

Elevated cholesterol is associated with breast cancer risk

Walk-in clinics staffed by nurses can reduce health care costs, says URI professor

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer

Brown fat stem cells may lead to new treatments for heart and endocrine disorders

Doctor-patient communication critical for success of patient-centered medical homes

Patients at highest risk for suffering full-blown ischemic attack less likely to receive optimal care

Chronic diseases account for increasing proportion of GPs' workload

Measuring BMI can help predict diabetic patient's risk for heart disease

Study finds consistent sleep pattern can reduce risk of illness among adolescents

HIVMA's updated HIV care guidelines show doctors should focus on common health conditions

Few newly diagnosed high-cholesterol patients get screened for thyroid dysfunction: Study

Results announced for Phase 3B/4 study of RAPAMUNE in kidney transplant patients

Obesity, overweight are risk factors for MI and IHD regardless of metabolic syndrome

Atrial fibrillation doubles risk of heart attack in women and African Americans

Most severely obese teenagers who underwent bariatric WLS experience no major complications

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