Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Researchers uncover how cancer cells override environmental cues to consume energy

Using human lung cancer cells, UT Southwestern researchers have uncovered how cells in general modulate their energy consumption based on their surroundings and, furthermore, how cancer cells override those cues to maximize energy use.

24 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

New biomarkers for diagnosis and prognosis of lung cancer identified

Applying bioinformatics to resolve biological problems. This is the objective of the research group of the University of Malaga "BI4NEXT", which, in one of its latest studies, developed in the Supercomputing and Bioinnovation Center based on biobank samples, has identified new biomarkers for the diagnosis, prognosis and even treatment of lung cancer.

20 Feb 2020

An enriched environment helps heal young, injured brains

An enriched environment--with increased opportunities for physical activity, socialization and exploring novel stimuli--helped lessen functional, anatomical and cellular deficits in an experimental model of brain damage caused by oxygen deprivation at birth.

19 Feb 2020

DuPont Nutrition & Biosciences partners with microbiome specialist MRM Health

DuPont Nutrition & Biosciences today announced a collaboration with the MRM Health NV, a biopharmaceutical company, focused on the discovery and development of innovative therapeutics based on the human microbiome.

From DuPont 19 Feb 2020

Supersensitive nanomaterials hold promise for DNA analysis and next-generation drugs

In 1900, German physician Paul Ehrlich came up with the notion of a "magic bullet." The basic idea is to inject a patient with smart particles capable of finding, recognizing, and treating a disease. Medicine has pursued the magic bullet ever since.

19 Feb 2020

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

UT Southwestern Medical Center data scientists analyzing genetic sequences of the COVID-19 coronavirus have identified potential vulnerabilities that could help in vaccine development and further study of the infectious disease now spreading worldwide.

17 Feb 2020

Targeting one's internal clock could prevent or slow breast cancer progression

City of Hope scientists have identified an unlikely way to potentially prevent or slow the progression of aggressive breast cancer: target one's internal clock.

13 Feb 2020

New method to measure mutations in father's sperm may reveal ASD risk in future children

While the causes of autism spectrum disorder are not fully understood, researchers believe both genetics and environment play a role.

13 Feb 2020

Surprising discovery about childhood brain tumor may unlock new cancer treatments

A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer and, potentially, many others.

13 Feb 2020

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting them to the tumor, where they fuel growth and cancer progression, researchers from The University of Texas MD Anderson Cancer Center report in the journal Nature today.

13 Feb 2020

Natural product from a fungus could shed light on cellular interactions prominent in cancer

A fungus that attacks almond and peach trees may be key to identifying new drug targets for cancer therapy.

12 Feb 2020

Protein Data Bank archive releases new coronavirus protease structure

The Protein Data Bank archive, which contains more than 160,000 3D structures for proteins, DNA, and RNA, this month released a new Coronavirus protease structure following the recent coronavirus outbreak, an ongoing viral epidemic primarily affecting mainland China that now threatens to spread to populations in other parts of the world.

10 Feb 2020

Developing new approaches to fight against multi-resistant pathogens

Developing fundamentally new approaches against multi-resistant germs: This is the goal of the new Bavarian research network bayresq.net which started in January 2020.

9 Feb 2020

Genetic fingerprints could help identify cancer-causing culprits

Causes of cancer are being cataloged through an international study revealing the genetic fingerprints of DNA-damaging processes that drive cancer development.

6 Feb 2020

Cedars-Sinai researchers to study role of fat in promoting cancer spread to liver

A diagnosis of pancreatic or colon cancer often sparks dread about the disease's likely next destination: the liver. That's because liver metastasis is a leading cause of death in these patients.

6 Feb 2020

Researchers compile large catalog of cancer mutations

Mutations in 38 different types of cancer have been mapped by means of whole genome analysis by an international team of researchers from, amongst others, the University of Copenhagen, Aarhus University, Aarhus University Hospital, and Rigshospitalet.

6 Feb 2020

Study lays foundation for translating mitochondrial biology into clinical applications

A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the "powerhouse of the cell." Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis.

6 Feb 2020

Cancer mutations may arise decades before diagnosis

Researchers at EMBL's European Bioinformatics Institute and the Francis Crick Institute have analyzed the whole genomes of over 2600 tumors from 38 different cancer types to determine the chronology of genomic changes during cancer development.

5 Feb 2020

Developing tests for genetic signs could lead to earlier cancer detection

Early signs of cancer can appear years before diagnosis and developing tests for these genetic signs could provide new ways to spot cancer early, according to new research led by the Crick and EMBL-EBI, and supported by an international cancer genomics consortium, the Pan-Cancer Analysis of Whole Genomes Project.

4 Feb 2020

Bioinformatics News and Research

Further Reading

Researchers uncover how cancer cells override environmental cues to consume energy

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

New biomarkers for diagnosis and prognosis of lung cancer identified

An enriched environment helps heal young, injured brains

DuPont Nutrition & Biosciences partners with microbiome specialist MRM Health

Supersensitive nanomaterials hold promise for DNA analysis and next-generation drugs

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

Targeting one's internal clock could prevent or slow breast cancer progression

New method to measure mutations in father's sperm may reveal ASD risk in future children

Surprising discovery about childhood brain tumor may unlock new cancer treatments

P53-deficient oral cancers recruit and reprogram nerves to fuel tumor growth

Natural product from a fungus could shed light on cellular interactions prominent in cancer

Protein Data Bank archive releases new coronavirus protease structure

Developing new approaches to fight against multi-resistant pathogens

Genetic fingerprints could help identify cancer-causing culprits

Cedars-Sinai researchers to study role of fat in promoting cancer spread to liver

Researchers compile large catalog of cancer mutations

Study lays foundation for translating mitochondrial biology into clinical applications

Cancer mutations may arise decades before diagnosis

Developing tests for genetic signs could lead to earlier cancer detection

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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