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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Precision medicine trial shows analysing person's DNA improves treatment options for cancer patients

A clinical trial for types of advanced cancer is the first of its kind to show that precision medicine - or tailoring treatment for individual people - can slow down the time it takes for a tumour to grow back, according to research presented at the Molecular Analysis for Personalised Therapy (MAP) conference, today (Friday).

23 Sep 2016

ASHG and Mayo Clinic collaborate to facilitate genetic and genomic education

The American Society of Human Genetics and Mayo Clinic Center for Individualized Medicine announced today a formal collaboration under which the two organizations will facilitate the use of genomics in medicine through the education of health professionals.

23 Sep 2016

Some people may have youthful DNA despite old age, study shows

The DNA of young people is regulated to express the right genes at the right time. With the passing of years, the regulation of the DNA gradually gets disrupted, which is an important cause of ageing.

23 Sep 2016

Tumour suppressor gene has greater anti-cancer activity than previously thought

New insight into the function of a gene important in the suppression of cancer is published today. Researchers at the National University of Ireland Galway have shown that the TP53 gene has even greater anti-cancer activity than previously thought.

22 Sep 2016

Scientists discover genomic alterations in pediatric relapsed ALL

A group of researchers from Columbia University, Rutgers University, and institutions in Europe and Japan have identified genomic alterations in pediatric relapsed acute lymphoblastic leukemia (ALL) that cause both therapy resistance and improved clinical response to multi-agent chemotherapy treatment.

22 Sep 2016

Duke researchers discover blood markers linked to drug-resistant tumor cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies.

21 Sep 2016

Scientists engineer smallest-reported synthetic virus that may help advance gene therapy

Gene therapy is a kind of experimental treatment that is designed to fix faulty genetic material and help a patient fight off or recover from a disease.

21 Sep 2016

Sanger Institute partners with St. Jude to support discovery, understanding of genetic mutations in paediatric cancers

The Wellcome Trust Sanger Institute is combining the power of COSMIC, its large-scale cancer genetics database, with ProteinPaint data mining and visualization system at St. Jude Children’s Research Hospital in Memphis TN, to support the discovery and understanding of genetic mutations in paediatric cancers.

21 Sep 2016

Genetic testing of mtDNA may reveal unknown ancestry that influences risk for breast cancer

Genetic testing of mitochondrial DNA could reveal otherwise unknown ancestry that can influence a person's risk for certain types of breast cancer, a new study finds.

21 Sep 2016

Study suggests interactions between distant DNA regions may impact disease gene levels

A person's DNA sequence can provide a lot of information about how genes are turned on and off, but new research out of Case Western Reserve University School of Medicine suggests the 3-D structure DNA forms as it crams into cells may provide an additional layer of gene control.

21 Sep 2016

Researchers use novel technique to unravel key mystery of earliest stage of development

A Ludwig Cancer Research study published online September 14th in Nature reports a novel technique to map specific chemical (or "epigenetic") modifications made to the protein packaging of DNA using a small population of cells.

20 Sep 2016

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

An international team of researchers who discovered a new gene disorder that causes severe childhood epilepsy leveraged that finding to reduce seizures in two children.

20 Sep 2016

Researchers identify genetic switch that may be potential target for Alzheimer's disease

A team at the MRC Clinical Sciences Centre, based at Imperial College London, has found an important part of the machinery that switches on a gene known to protect against Alzheimer's Disease.

20 Sep 2016

Scientists begin research work at new £650 million Francis Crick Institute building

The first scientists have moved into the new £650 million Francis Crick Institute building in London and are starting work in their purpose-built labs.

20 Sep 2016

IU receives $1.9 million grant to investigate effects of congenital birth defects and age on the eye

A $1.9 million grant to Indiana University from the National Institutes of Health's National Eye Institute will advance basic research on the eye with applications to blindness caused by genetic disorders and aging.

20 Sep 2016

Researchers identify mutant traits in mouse for many human disease genes

About one-third of all genes in the mammalian genome are essential for life. An international, multi-institutional research collaboration identified, for the first time, mutant traits in the mouse for 52 human disease genes, which significantly contributes to the understanding of the genetic bases for some human diseases, including cardiovascular defects, spina bifida, and metabolic disorders, among many others. The study was published this week in Nature.

19 Sep 2016

New less invasive method could detect bacterial infection in young febrile infants

Physicians from Children's Hospital of Michigan, Wayne State University, UC Davis Medical Center and Nationwide Children's Hospital, in collaboration with 19 other pediatric emergency departments around the country, have established a "proof of principle" for measuring patterns of ribonucleic acid (RNA) expression in the bloodstream that can enable clinicians to distinguish bacterial infections from other causes of fever in infants up to two months old.

19 Sep 2016

Memory of heart attack can be stored in genes through epigenetic changes, study shows

Both heredity and environmental factors influence our risk of cardiovascular disease. A new study, by researches at Uppsala University, shows now that the memory of a heart attack can be stored in our genes through epigenetic changes.

19 Sep 2016

Chromatrap reports benefits of using ChIP-seq kit for histone methylation applications

Chromatrap reports on the advantages of using its Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits for histone methylation applications.

From Chromatrap® - Porvair Sciences Ltd 16 Sep 2016

Researchers identify and treat new variant of antibiotic-resistant E. coli

Researchers at Massachusetts Eye and Ear have discovered a new mutation in a highly antibiotic-resistant strain of E. coli that resists clearance by the body's own immune system by inhibiting white blood cells that ordinarily kill and remove bacteria.

16 Sep 2016

DNA News and Research

Further Reading

Precision medicine trial shows analysing person's DNA improves treatment options for cancer patients

ASHG and Mayo Clinic collaborate to facilitate genetic and genomic education

Some people may have youthful DNA despite old age, study shows

Tumour suppressor gene has greater anti-cancer activity than previously thought

Scientists discover genomic alterations in pediatric relapsed ALL

Duke researchers discover blood markers linked to drug-resistant tumor cells

Scientists engineer smallest-reported synthetic virus that may help advance gene therapy

Sanger Institute partners with St. Jude to support discovery, understanding of genetic mutations in paediatric cancers

Genetic testing of mtDNA may reveal unknown ancestry that influences risk for breast cancer

Study suggests interactions between distant DNA regions may impact disease gene levels

Researchers use novel technique to unravel key mystery of earliest stage of development

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

Researchers identify genetic switch that may be potential target for Alzheimer's disease

Scientists begin research work at new £650 million Francis Crick Institute building

IU receives $1.9 million grant to investigate effects of congenital birth defects and age on the eye

Researchers identify mutant traits in mouse for many human disease genes

New less invasive method could detect bacterial infection in young febrile infants

Memory of heart attack can be stored in genes through epigenetic changes, study shows

Chromatrap reports benefits of using ChIP-seq kit for histone methylation applications

Researchers identify and treat new variant of antibiotic-resistant E. coli

eBook: A guide to RNA sequencing eBook

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