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New strategy can reactivate genes that cause cancer tumors to shrink and die

A team of scientists has developed a promising new strategy for "reactivating" genes that cause cancer tumors to shrink and die. The researchers hope that their discovery will aid in the development of an innovative anti-cancer drug that effectively targets unhealthy, cancerous tissue without damaging healthy, non-cancerous tissue and vital organs.

22 May 2012

MGH develops new technique to reconstruct the larynx after surgery for advanced cancer

Massachusetts General Hospital (MGH) surgeons have developed a new technique for reconstructing the larynx after surgery for advanced cancer.

22 May 2012

Scientists unravel action mechanism of castor oil

Castor oil is known primarily as an effective laxative; however, it was also used in ancient times with pregnant women to induce labour. Only now have scientists at the Max Planck Institute for Heart and Lung Research succeeded in unravelling the mysteries of the action mechanism. A receptor by the name of EP3 on the cells of the intestine and uterus is apparently responsible. This is activated by an ingredient in the oil.

22 May 2012

$Children with pelvic and thigh fractures rarely develop dangerous blood clots$

Children with pelvic and thigh fractures rarely develop dangerous blood clots

Children with pelvic and thigh fractures develop dangerous blood clots so rarely that anti-clotting therapy should be given only to those with underlying conditions that increase clotting risk, according to a study from Johns Hopkins Children's Center.

21 May 2012

Young children with cystic fibrosis do not benefit from concentrated saline therapy

Concentrated saline therapy not effective in young children with cystic fibrosis NIH-funded study demonstrates importance of conducting pediatric clinical trials.

21 May 2012

Tuberculosis independently predicts death from lung cancer in the elderly

Tuberculosis independently predicts death from lung cancer in the elderly, according to a new study from researchers in Hong Kong.

21 May 2012

Dyspnea limits sexual activity among older patients with COPD

Troublesome dyspnea that limits sexual activity is common among older patients with COPD, according to a new study from Denmark.

21 May 2012

$Anti-clotting drugs rarely needed in children with big-bone fractures$

Anti-clotting drugs rarely needed in children with big-bone fractures

21 May 2012

Biomarker neutralizes effect of bevacizumab in pancreas and kidney cancer patients

Diether Lambrechts (VIB - KU Leuven) said "in two large clinical studies with patients with advanced stages of pancreas and kidney cancer a variant in the DNA was discovered that identified patients who did not respond well to the prescribed course of bevacizumab.

21 May 2012

Prenatal exposure to air pollution can be serious for children with asthma

The link between prenatal exposure to air pollution and childhood lung growth and respiratory ailments has been established by several studies in recent years, and now a new study suggests that these prenatal exposures can be especially serious for children with asthma.

21 May 2012

Statin therapy prevents cancer and reduces death risk in heart transplant recipients

Statins prevent cancer and reduce death from all causes in heart transplant recipients. The findings were independent of cholesterol levels.

21 May 2012

Exposure to parental smoking increases risk of respiratory symptoms in children

For more than three decades, researchers have warned of the potential health risks associated with exposure to environmental tobacco smoke (ETS), especially among children whose parents smoke. Now a new study conducted by researchers from the University of Arizona reports that those health risks persist well beyond childhood, independent of whether or not those individuals end up becoming smokers later in life.

21 May 2012

Review examines benefits and harms of LDCT screening for lung cancer

Peter B. Bach, M.D., of the Memorial Sloan-Kettering Cancer Center, New York, and colleagues conducted a systematic review to examine the evidence regarding the benefits and harms of low-dose computerized tomography (LDCT) screening for lung cancer, which is the leading cause of cancer death. "Most patients are diagnosed with advanced disease, resulting in a very low 5-year survival rate," the authors write.

21 May 2012

Osteopenia/osteoporosis more prevalent among male patients with pulmonary disease

There is a very high prevalence of osteopenia/osteoporosis among male patients with pulmonary disease, according to a new study from researchers in California.

21 May 2012

Three-drug combo harmful for patients with idiopathic pulmonary fibrosis

A combination of three drugs used worldwide as the standard of care for a serious lung disease puts patients in danger of death or hospitalization, and should not be used together to treat the disease, called idiopathic pulmonary fibrosis, according to the surprising results of a rigorous independent study.

21 May 2012

LKCF, Spirit of Women’s HeartCaring to help reduce disparities in diagnosis and care

In an ongoing effort to save the lives of thousands of Americans at risk of cardiovascular ailments each year, Spirit of Women Health Network has joined forces with the Larry King Cardiac Foundation (LKCF) to help reduce the devastating disparity in the diagnostics, clinical care, and survival rate of heart attacks, strokes and other heart events for women and people of color.

19 May 2012

Placental stem cells with key therapeutic properties can be harvested from chorion

Scientists at Children's Hospital Oakland Research Institute (CHORI) led by Vladimir Serikov, MD, PhD, and Frans Kuypers, PhD, report in the current Epub issue of Stem Cells Translational Medicine that placental stem cells with important therapeutic properties can be harvested in large quantities from the fetal side of human term placentas.

19 May 2012

New study to find best way to give blood transfusions for severely injured patients

Researchers at The University of Texas Health Science Center at Houston (UTHealth) are launching a new research study to find the best way to give blood transfusions for severely injured patients predicted to require massive blood transfusions upon arrival to the Memorial Hermann-Texas Medical Center emergency department. Bryan Cotton, M.D., of UTHealth is principal investigator for this clinical study.

19 May 2012

Daiichi Sankyo, ArQule complete enrollment in tivantinib plus erlotinib Phase 3 NSCLC trial

ArQule, Inc. and Daiichi Sankyo, Co., Ltd. today announced that recruitment of patients has been completed in the randomized, double-blind, controlled Phase 3 MARQUEE pivotal trial of their investigational selective c-MET inhibitor, tivantinib, in combination with erlotinib in previously treated patients with locally advanced or metastatic, non-squamous, non-small cell lung cancer.

19 May 2012

Personal genetic test results does not drive overuse of expensive medical care

People have increasing opportunities to participate in genetic testing that can indicate their range of risk for developing a disease. Receiving these results does not appreciably drive up or diminish test recipients' demand for potentially costly follow-up health services, according to a study performed by researchers at the National Institutes of Health and colleagues at other institutions.

19 May 2012

Lungs News and Research

New strategy can reactivate genes that cause cancer tumors to shrink and die

MGH develops new technique to reconstruct the larynx after surgery for advanced cancer

Scientists unravel action mechanism of castor oil

Children with pelvic and thigh fractures rarely develop dangerous blood clots

Young children with cystic fibrosis do not benefit from concentrated saline therapy

Tuberculosis independently predicts death from lung cancer in the elderly

Dyspnea limits sexual activity among older patients with COPD

Anti-clotting drugs rarely needed in children with big-bone fractures

Biomarker neutralizes effect of bevacizumab in pancreas and kidney cancer patients

Prenatal exposure to air pollution can be serious for children with asthma

Statin therapy prevents cancer and reduces death risk in heart transplant recipients

Exposure to parental smoking increases risk of respiratory symptoms in children

Review examines benefits and harms of LDCT screening for lung cancer

Osteopenia/osteoporosis more prevalent among male patients with pulmonary disease

Three-drug combo harmful for patients with idiopathic pulmonary fibrosis

LKCF, Spirit of Women’s HeartCaring to help reduce disparities in diagnosis and care

Placental stem cells with key therapeutic properties can be harvested from chorion

New study to find best way to give blood transfusions for severely injured patients

Daiichi Sankyo, ArQule complete enrollment in tivantinib plus erlotinib Phase 3 NSCLC trial

Personal genetic test results does not drive overuse of expensive medical care

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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