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Bath researchers identify promising prostate cancer drug candidates

Cancer researchers from the University of Bath have identified some promising drug candidates by using high-throughput screening methods to test tens of thousands of molecules.

24 Sep 2019

Mice also fidget like humans while making decisions

Almost everyone fidgets, said Cold Spring Harbor Laboratory Associate Professor Anne Churchland. She referred to a collage of videos she compiled of different people rocking back and forth in their chairs, clicking a pen, shaking their legs.

24 Sep 2019

Non-viral gene delivery method more effective and safer than standard viral approaches

The non-viral, bio-inspired gene delivery method developed by researchers at RMIT University has proven effective in laboratory tests and is safer than standard viral approaches.

24 Sep 2019

$Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus$

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

Researchers from the University of California San Francisco and Veterans Affairs Health Care System, San Francisco investigated the safety and efficacy of deep brain stimulation in the treatment of refractory severe tinnitus in a small group of patients.

24 Sep 2019

Penn State scientists receive AHA grant, propose new way to prevent thrombosis

Two Penn State biomedical engineering faculty members have received a two-year, $200,000 grant from the American Heart Association (AHA) to explore potential solutions to thrombosis, or blood clot formation, a prevalent issue with blood-contacting medical devices such as heart valves, blood pumps and cardiac stents.

24 Sep 2019

New AGA guideline on evaluation of chronic diarrhea released

Diagnosing patients with chronic watery diarrhea can be difficult for health care providers, since several causes with specific therapies, such as inflammatory bowel disease (IBD), microscopic colitis and chronic infection, need to be ruled out.

23 Sep 2019

Ruthenium probes shed new light on cause of Alzheimer's disease

Rice University researchers have found a way to track the formation of soluble amyloid beta peptide aggregates implicated in the onset of Alzheimer's disease.

23 Sep 2019

Study sheds light on mechanisms behind correlated electrical activity in neurons

"Like a book in which the single pages are not all different but carry small portions of common text, or like a group of people who whistle a very similar tune": this is how our brain cells work, say scientists. It is the phenomenon of "co-relation", in which individual neurons do not always act as independent units in receiving and transmitting information but as a group of individuals with similar and simultaneous actions.

23 Sep 2019

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

Versions of an antibiotic drug called DON first isolated from soil bacteria more than 60 years ago have shown promising signs of extending survival in mice models of especially lethal pediatric brain tumors marked by the high expression of a cancer-causing gene known as the MYC oncogene, according to results of two studies from researchers at the Johns Hopkins Kimmel Cancer Center.

23 Sep 2019

U-M and Karmanos receive NCI grant to find new solutions for prostate cancer

Michigan's two elite cancer programs are joining forces to find new solutions for prostate cancer. The University of Michigan Rogel Cancer and the Barbara Ann Karmanos Cancer Institute have received a prestigious $9.2 million grant from the National Cancer Institute.

23 Sep 2019

Tanzania keeping Ebola under wraps

Ebola could be already on the prowl in Tanzania, but the government is keeping it a secret. This is the official position of the World Health Organization (WHO), who says multiple cases have been secretly reported to it.

23 Sep 2019

African bacterium resists almost all drugs

It looks like it’s time to pay the piper. The first extensively drug-resistant (XDR) strain of Salmonella typhimurium, called ST313 sublineage II.1, has cropped up in the Democratic Republic of Congo (DRC). This fails to respond to any of the antibiotics that are commonly used in the DRC, except for ciprofloxacin. And to make things worse, one sample has been isolated that shows incomplete response even to this last drug.

22 Sep 2019

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

Dengue virus infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions.

20 Sep 2019

NIH awards research grants to develop learning health care system for early psychosis treatment

The National Institutes of Health awarded six research grants for studies to develop a learning health care system for the treatment of early psychosis.

20 Sep 2019

Smoking abstinence does not greatly affect motivation for food, research suggests

It's sometimes thought that smokers who can't light up are likely to reach for food in lieu of cigarettes. But new research from the University at Buffalo suggests that smoking abstinence doesn't greatly affect the motivation for food.

20 Sep 2019

Developing cost-effective and milder synthetic routes to create oxygen heterocycles

Every biological reaction is a chemical reaction. The exchange of carbon dioxide for oxygen in our lungs and blood cells, for example, is caused by molecules releasing chemicals and reforming with new ones.

20 Sep 2019

Discovery of combination protein leads to first-in-human clinical trial for leukemia

The discovery of tri-specific natural killer engagers (TriKE™), a combination protein that bridges an immune cell and a tumor cell to drive tumor cell killing power exponentially, has led to a new Phase I, first-in-human study to treat leukemia.

20 Sep 2019

Mitochondrial fission factor could represent a promising target for cancer therapy

Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found that expression of MFF is regulated by Myc, a ubiquitous mediator of cell proliferation that contributes to development of many cancer types.

20 Sep 2019

Hedgehogs carry mecC-MRSA that causes infection in Danish patients

Most people consider the hedgehog a welcome guest in the garden. But a newly published study reveals that the Danish hedgehogs carry a secret.

20 Sep 2019

Daniel Weinberger wins NAM's Sarnat Prize for schizophrenia research

The National Academy of Medicine today announced Daniel Weinberger is the recipient of the 2019 Rhoda and Bernard Sarnat International Prize in Mental Health, for his fundamental role in elucidating the biological origins and genetic expressions of schizophrenia, and for transforming how clinicians, researchers, and the public understand mental illness.

19 Sep 2019

Laboratory News and Research

Bath researchers identify promising prostate cancer drug candidates

Mice also fidget like humans while making decisions

Non-viral gene delivery method more effective and safer than standard viral approaches

Deep brain stimulation found to be safe, effective in the treatment of refractory severe tinnitus

Penn State scientists receive AHA grant, propose new way to prevent thrombosis

New AGA guideline on evaluation of chronic diarrhea released

Ruthenium probes shed new light on cause of Alzheimer's disease

Study sheds light on mechanisms behind correlated electrical activity in neurons

Version of an antibiotic drug extends survival in mice with lethal pediatric brain tumors

U-M and Karmanos receive NCI grant to find new solutions for prostate cancer

Tanzania keeping Ebola under wraps

African bacterium resists almost all drugs

Mutations in specific protein make dengue virus resistant to vaccines and therapeutics

NIH awards research grants to develop learning health care system for early psychosis treatment

Smoking abstinence does not greatly affect motivation for food, research suggests

Developing cost-effective and milder synthetic routes to create oxygen heterocycles

Discovery of combination protein leads to first-in-human clinical trial for leukemia

Mitochondrial fission factor could represent a promising target for cancer therapy

Hedgehogs carry mecC-MRSA that causes infection in Danish patients

Daniel Weinberger wins NAM's Sarnat Prize for schizophrenia research

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