DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study sheds light on origins of breast cancer in people with BRCA2 mutations

A pioneering study led by Professor Ashok Venkitaraman from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and Dr Mona Shehata from the University of Cambridge (UK) has uncovered vital insights into the distinct effects of BRCA2 mutations on breast tissue cells, shedding light on early breast cancer development in people with BRCA2 mutations.

1 Nov 2023

Added calcium and phosphate in fluoride varnishes no silver bullet for fighting kids' tooth decay, study finds

The study explores the effectiveness of sodium fluoride varnishes with added calcium and phosphate versus conventional varnishes in reducing harmful bacteria in preschool children's mouths. Results indicate no significant difference between the two types of varnishes in controlling bacterial growth, calling for more research on effective ways to combat early childhood caries.

1 Nov 2023

New study provides insights about mosaic chromosomal alterations in diverse populations

As people age, the DNA in their cells begins to accumulate genetic mutations. Mosaic chromosomal alterations (mCAs), a category of mutations acquired in blood cells, are linked with a 10-fold increased risk of developing blood cancer.

1 Nov 2023

Study finds epigenetic signature for obesity susceptibility in human twins

A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.

1 Nov 2023

New gene editing method creates first mice with human-like COVID-19

Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a study published online November 1 in Nature.

1 Nov 2023

PacBio announces Kinnex RNA Kits, further scaling HiFi Sequencing in Full-Length RNA, Single-Cell RNA and 16S rRNA applications

PacBio today announced it has begun taking orders for its groundbreaking Kinnex RNA kits, which increase throughput for full-length RNA, single-cell RNA, and 16S rRNA sequencing on PacBio’s long-read sequencing systems to enable large-scale studies at a resolution difficult to attain with short-read RNA sequencing.

From PacBio 1 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

3D organization of DNA can influence glioblastoma progression, study reveals

A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumor known as glioblastoma.

1 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

Sickle cell disease patients willing to accept high risks for gene therapy cure

Individuals living with severe sickle cell disease (SCD) are highly interested in new, potentially curative gene therapy treatments and are willing to accept associated risks for a chance at a cure, according to a study published today in Blood Advances.

31 Oct 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

The lungs were once at the forefront of SARS-Cov-2 research, but as reports of organ failure and other serious complications poured in, scientists set out to discover how and why the respiratory virus was causing serious damage to the body's major organs, including the lungs.

31 Oct 2023

New drug gets FDA approval for the treatment of common genetic disease in young boys

A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys.

31 Oct 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

Broken String Biosciences today announced that its INDUCE-seq™ DNA break-mapping technology had been used in a peer-reviewed research paper to characterize off-target effects of CRISPR-Cas9 gene editing resulting from changes in DNA topology.

From Broken String Biosciences 31 Oct 2023

Promising new drug target for triple-negative breast cancer identified

Previous
1
...
50
51
52
53
54
55
56
...
1195
Next

DNA News and Research

Further Reading

Study sheds light on origins of breast cancer in people with BRCA2 mutations

Added calcium and phosphate in fluoride varnishes no silver bullet for fighting kids' tooth decay, study finds

New study provides insights about mosaic chromosomal alterations in diverse populations

Study finds epigenetic signature for obesity susceptibility in human twins

New gene editing method creates first mice with human-like COVID-19

PacBio announces Kinnex RNA Kits, further scaling HiFi Sequencing in Full-Length RNA, Single-Cell RNA and 16S rRNA applications

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

3D organization of DNA can influence glioblastoma progression, study reveals

How one gene shakes up our understanding of male infertility

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

Sickle cell disease patients willing to accept high risks for gene therapy cure

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

New drug gets FDA approval for the treatment of common genetic disease in young boys

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

Promising new drug target for triple-negative breast cancer identified

New MECP2 gene variant identified and characterized in Rett syndrome

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

New bivalent vaccine shows promising results against key fish pathogens

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Latest Life Science News