Transplant News and Research

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An Introduction to the Benefits of the Skin Trust Club

In this interview, News-Medical speaks to Dr. David Caballero-Lima, Head of R&D at Labskin, about the applications and benefits of the Skin Trust Club.

11 May 2021

Experimental gene therapy successfully treats children born without an immune system

An experimental form of gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with a rare and deadly inherited disorder that leaves them without an immune system.

11 May 2021

Immunosuppression in COVID-19 promotes emergence of multiple immune escape mutants

An interesting new study describes the emergence of several such variants from a chronically immunosuppressed COVID-19 patient, who remained infected for over 170 days before clearing the virus.

7 May 2021

Study may lead to personalized treatments for cystic fibrosis

Some 2,103 mutations have been identified in patients with cystic fibrosis (CF), the most common fatal genetic disease in Canada, and together they pose huge challenges for patients and researchers, including those affiliated with Université de Montreal and its teaching hospital, the Centre hospitalier de l'Université de Montréal (CHUM).

7 May 2021

Transplant recipients with COVID-19 may show lower cellular and antibody immune responses

Transplant patients are typically on chronic immunosuppression, making them automatically more vulnerable to infection with SARS-CoV-2, the agent responsible for the loss of over three million lives in the current COVID-19 pandemic. A new study discusses evidence for subnormal immune responses following COVID-19 in this population.

6 May 2021

Many adults with hypertension may be taking other medications that could raise blood pressure

Nearly 1 in 5 adults with high blood pressure, a leading risk factor for heart disease and stroke, also take a medicine that could be elevating their blood pressure, according to new research presented at the American College of Cardiology's 70th Annual Scientific Session.

6 May 2021

Study: Second vaccine dose still makes organ transplant recipients vulnerable to COVID-19

In a study published today in the Journal of the American Medical Association (JAMA), Johns Hopkins Medicine researchers show that although two doses of a vaccine against SARS-CoV-2 -; the virus that causes COVID 19 -; confers some protection for people who have received solid organ transplants, it's still not enough to enable them to dispense with masks, physical distancing and other safety measures.

6 May 2021

Study could pave way for new therapies for kidney disease

Our kidneys are charged with the extraordinary task of filtering about 53 gallons of fluid a day, a process that depends on podocytes, tiny, highly specialized cells in the cluster of blood vessels in the kidney where waste is filtered that are highly vulnerable to damage.

5 May 2021

ATS publishes new clinical practice guideline on community-acquired pneumonia

In its latest clinical practice guideline on community-acquired pneumonia the American Thoracic Society's guidelines panel addresses the use of nucleic acid-based testing for non-influenza viral pathogens.

4 May 2021

Study reveals major factors that affect bone health in hematopoietic stem cell transplantation recipients

Impaired bone health is among the most significant long-term consequences of hematopoietic stem cell transplantation (HSCT), a common therapy for patients with malignant and non-malignant hematological diseases.

4 May 2021

Study shows that heart transplantation using donation after cardiac death with NRP is feasible in the U.S.

A new study, presented today at the AATS 101st Annual Meeting, found that heart transplantation using donation after cardiac death (DCD) with normothermic regional perfusion (NRP) is feasible in the United States.

3 May 2021

Antiviral T cells safe, effective as off-the-shelf therapy for painful complication after stem cell transplants

A Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center found that BK virus (BKV)-specific T cells from healthy donors were safe and effective as an off-the-shelf therapy for BKV-associated hemorrhagic cystitis (BKV-HC), a painful complication common after allogeneic stem cell transplants for patients with leukemia or lymphoma.

30 Apr 2021

Cleveland Clinic, Lifebanc and Transplant Connect launch a fully automated donor referral system

Cleveland Clinic, Lifebanc and Transplant Connect have designed and launched a fully automated donor referral system to streamline the process for hospital staff identifying and evaluating potential organ, tissue and eye donors.

30 Apr 2021

Cell-free DNA tests can reduce the need for biopsies to detect rejection after heart transplant

A new study, presented today at the AATS 101st Annual Meeting, shows that non-invasive cell-free DNA tests can reduce the need for regular surveillance biopsies to detect early rejection in heart transplant patients. The study was the first of its kind to be performed on both adult and pediatric patients.

30 Apr 2021

Simple device can reduce swelling after kidney transplantation

In a published study, a team from Lawson Health Research Institute has found that a simple device can reduce swelling after kidney transplantation.

29 Apr 2021

New discovery could lead to more effective treatments for fatigue-inducing anemias

A combination of inexpensive oral medications may be able to treat fatigue-inducing anemias caused by chronic diseases and inflammation, a new discovery from the University of Virginia School of Medicine suggests.

27 Apr 2021

Study raises concern about limited immune response of transplant patients after COVID-19 vaccination

A small study from Mayo Clinic researchers raises the concern that some transplant patients may have a limited immune response after being vaccinated for COVID-19 with an mRNA vaccine.

26 Apr 2021

University of Minnesota to host new Organ and Tissue Preservation Center

The University of Minnesota is one of two institutions in the United States to host a new center established by the Biostasis Research Institute aimed at creating human organ banks through the cryogenic storage of organs donated for transplantation.

22 Apr 2021

Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Making stem cell transplants safer and more effective

For cancer patients, the use of hematopoietic stem cell transplants can be a game changer in terms of treatment and recovery.

21 Apr 2021

Transplant News and Research

An Introduction to the Benefits of the Skin Trust Club

Experimental gene therapy successfully treats children born without an immune system

Immunosuppression in COVID-19 promotes emergence of multiple immune escape mutants

Study may lead to personalized treatments for cystic fibrosis

Transplant recipients with COVID-19 may show lower cellular and antibody immune responses

Many adults with hypertension may be taking other medications that could raise blood pressure

Study: Second vaccine dose still makes organ transplant recipients vulnerable to COVID-19

Study could pave way for new therapies for kidney disease

ATS publishes new clinical practice guideline on community-acquired pneumonia

Study reveals major factors that affect bone health in hematopoietic stem cell transplantation recipients

Study shows that heart transplantation using donation after cardiac death with NRP is feasible in the U.S.

Antiviral T cells safe, effective as off-the-shelf therapy for painful complication after stem cell transplants

Cleveland Clinic, Lifebanc and Transplant Connect launch a fully automated donor referral system

Cell-free DNA tests can reduce the need for biopsies to detect rejection after heart transplant

Simple device can reduce swelling after kidney transplantation

New discovery could lead to more effective treatments for fatigue-inducing anemias

Study raises concern about limited immune response of transplant patients after COVID-19 vaccination

University of Minnesota to host new Organ and Tissue Preservation Center

Novel approach to gene editing bypasses disease-causing mutations in a gene

Making stem cell transplants safer and more effective

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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