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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New method helps analyse how cold viruses penetrate into cells

Cold viruses cause us irritation by penetrating into our cells and transporting their RNA into the cytoplasma of the infected cells. This is the only way they can multiply. The details of how the transfer of the RNA from within the virus occurs are difficult to study.

20 Jun 2016

TUM scientists identify four new risk genes altered in MS patients

Scientists of the Technical University of Munich and the Max Planck Institute of Psychiatry have identified four new risk genes that are altered in German patients with multiple sclerosis (MS).

20 Jun 2016

Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Firstly, a sample must be transported from the clinic to the laboratory. Simple tests may be undertaken in a small lab within the hospital or clinic, whilst complex testing such as drug susceptibility testing is often done in a large centralized laboratory many miles from the clinic

20 Jun 2016

Scientists study fundamentals of tumour surveillance by immune system in mice models

The body's defences detect and eliminate not only pathogens but also tumour cells. Natural killer cells (NK-Cells) are specifically activated by chemical messengers, the Cytokines, to seek and destroy tumour cells.

20 Jun 2016

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Somatic mutations in the helicase-encoding ERCC2 gene are associated with response to neoadjuvant cisplatin-based chemotherapy in patients with muscle-invasive urothelial bladder carcinoma.

17 Jun 2016

Delivery mode, exposure to antibiotics and feeding method linked to change in baby's microbial communities

Birth by C-section, exposure to antibiotics and formula feeding slow the development and decrease the diversity of a baby's microbes through the first year of life. That is the finding of a study led by researchers from NYU Langone Medical Center and published June 15 in the journal Science Translational Medicine.

17 Jun 2016

Researcher aims to develop easy-to-use, inexpensive sperm sorting devices to help infertile couples

The competition is fierce and only the strongest survive the obstacle course within the female reproductive tract. Of the millions of sperm that enter the vagina, only about 10 or so make it to the oocyte or egg, demonstrating how rigorous the natural sperm selection process really is.

17 Jun 2016

Mother's obesity can impair health of future generations

New research suggests that mothers who eat high-fat, high-sugar diets can predispose multiple generations to metabolic problems, even if their offspring consume healthy diets.

17 Jun 2016

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair damaged cells.

17 Jun 2016

Scientists develop new software program that can help compare large amounts of metagenomes

Scientists from ITMO University, the Federal Research and Clinical Centre of Physical-Chemical Medicine and MIPT have developed a software program enabling them to quickly compare sets of DNA of microorganisms living in different environments. The researchers have already suggested exactly how the new program could be applied in practice.

16 Jun 2016

Penn researchers help identify unique characteristics of reserve stem cells

Adult stem cells represent a sort of blank clay from which a myriad of different cell and tissue types are molded and as such are of critical importance to health, aging and disease.

16 Jun 2016

New electronic sensor can distinguish between dead and living bacteria cells

A new type of electronic sensor that might be used to quickly detect and classify bacteria for medical diagnostics and food safety has passed a key hurdle by distinguishing between dead and living bacteria cells.

15 Jun 2016

Genomic analysis can help public health investigators understand dynamics of TB outbreak

Using genome sequencing, researchers from the University of British Columbia, along with colleagues at the Imperial College in London, now have the ability to determine when a tuberculosis (TB) outbreak is over.

15 Jun 2016

QIAGEN announces launch of QIAsure Methylation Test to detect cervical cancer risk

QIAGEN N.V. today announced the launch of the QIAsure Methylation Test, a novel CE-marked molecular diagnostic test for use in differentiating patients' risk of developing cervical cancer.

From QIAGEN Manchester Limited 15 Jun 2016

Scientists aim to heal failing heart with the body’s own cells

Babies born with heart defects live longer than ever thanks to advances in the diagnosis and treatment of congenital heart disease. Yet, despite substantial progress, many continue to face bleak odds, lifelong medication, multiple surgeries and progressive heart failure, often requiring a transplant.

15 Jun 2016

Physical activity can counteract genetic risk linked to bone fragility in childhood

Exercise, particularly high-impact activity, builds stronger bones in children, even for those who carry genetic variants that predispose them to bone weakness, according to new research.

14 Jun 2016

Databases of proteins' 3-D shapes help identify more than 850 DNA mutations linked to cancer

Examining databases of proteins' 3-D shapes, scientists at Washington University School of Medicine in St. Louis have identified more than 850 DNA mutations that appear to be linked to cancer.

14 Jun 2016

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys.

14 Jun 2016

Study shows similarity between embryonic and reprogrammed stem cells

Stem cells are specialized undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth.

13 Jun 2016

Findings may help explain why rheumatoid arthritis drugs vary in effect

Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA.

12 Jun 2016

DNA News and Research

Further Reading

New method helps analyse how cold viruses penetrate into cells

TUM scientists identify four new risk genes altered in MS patients

Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Scientists study fundamentals of tumour surveillance by immune system in mice models

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Delivery mode, exposure to antibiotics and feeding method linked to change in baby's microbial communities

Researcher aims to develop easy-to-use, inexpensive sperm sorting devices to help infertile couples

Mother's obesity can impair health of future generations

Tumour protein TP53 can locate DNA targets autonomously to prevent cancer

Scientists develop new software program that can help compare large amounts of metagenomes

Penn researchers help identify unique characteristics of reserve stem cells

New electronic sensor can distinguish between dead and living bacteria cells

Genomic analysis can help public health investigators understand dynamics of TB outbreak

QIAGEN announces launch of QIAsure Methylation Test to detect cervical cancer risk

Scientists aim to heal failing heart with the body’s own cells

Physical activity can counteract genetic risk linked to bone fragility in childhood

Databases of proteins' 3-D shapes help identify more than 850 DNA mutations linked to cancer

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Study shows similarity between embryonic and reprogrammed stem cells

Findings may help explain why rheumatoid arthritis drugs vary in effect

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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