Birth Defects News and Research

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Heartburn drugs safe in pregnancy: Study

Pregnancy brings about a lot of heartburn sometimes beginning in the first trimester and continuing until delivery. To date the drugs available for general use in heartburn called proton-pump inhibitors or PPIs were wrought with safety concerns during pregnancy.

24 Nov 2010

U.S mortality rate from congenital heart defects drops 24%: Report

The U.S. death rate from congenital heart defects dropped 24 percent from 1999 to 2006 among children and adults, according to research reported in Circulation: Journal of the American Heart Association.

23 Nov 2010

Research shows association between childhood CKD and maternal diabetes, obesity

Children with Chronic Kidney Disease (CKD) are more likely to have mothers who were obese or had diabetes during pregnancy, according to a study presented at the American Society of Nephrology's 43rd Annual Meeting and Scientific Exposition, by Christine W. Hsu, MD (University of Washington, Seattle) and colleagues.

22 Nov 2010

Acne, acne medicine and mental health: Study

Acne drug Accutane (isotretinoin) has been plagued by serious controversies with some linking it to suicidal tendencies. Now the latest research finds that severe acne itself increases the risk for suicidal thoughts and actions, raising more questions about the role of the drug, if any, in suicide.

14 Nov 2010

New type of heart pump for infants born with univentricular circulation

Researchers have created a new type of heart pump inserted with a catheter to improve the survival rate for infants undergoing a series of surgeries to correct a deadly birth defect.

10 Nov 2010

Micronutrient Initiative receives $75 million to expand innovative nutrition programming

Minister of International Cooperation, Beverley Oda, has announced $75 million in new funding for the work of the Micronutrient Initiative to expand innovative nutrition programming and strengthen African health systems. The investment will be spread over five years and is expected to benefit 4 million pregnant women and 14 million children under the age of five - particularly in sub-Saharan Africa.

2 Nov 2010

GSN closes $12M Series C financing

Gene Security Network, Inc. today announced the closing of its $12M Series C financing. The financing round was led by Sequoia Capital and included Claremont Creek Ventures, Founders Fund, and Lightspeed Venture Partners.

2 Nov 2010

Even most vulnerable infants can transition to breast-feeding: Study

Pediatric researchers at The Children's Hospital of Philadelphia describe a successful program in which nurses helped mothers attain high rates of breast-feeding in very sick babies--newborns with complex birth defects requiring surgery and intensive care.

28 Oct 2010

New national campaign to drive awareness on DVT and PE prevention in women

As many as 600,000 people are affected by deep vein thrombosis (DVT) and pulmonary embolism (PE) every year, and more than half of those are never diagnosed. Some people experience swelling and varying levels of discomfort in the affected area, and some don't feel anything at all. But the symptoms of DVT can be similar to other conditions, like a pulled muscle, and because some people with DVT do not have any symptoms, there is often a delay in diagnosis. That's when DVT can be fatal.

28 Oct 2010

Researchers investigate impact of fungal toxin on birth defects

A Creighton University School of Medicine researcher has been awarded a $2.7 million grant by the National Institutes of Health (NIH) to investigate a possible link between the ingestion of tortillas and corn-based food products contaminated with a fungal toxin and increased risk for birth defects.

26 Oct 2010

GSN initiates trial of microarray PGD on pregnancy and implantation rates in IVF

Gene Security Network (GSN) announced today that it has initiated enrollment for a prospective randomized trial in collaboration with Ferring Pharmaceuticals to evaluate the impact of GSN's advanced preimplantation genetic diagnosis (PGD) with Parental Support™ on pregnancy and implantation rates in IVF.

25 Oct 2010

Research on worms may help develop ways to maintain fertility in humans

Princeton scientists have identified genes responsible for controlling reproductive life span in worms and found they may control genes regulating similar functions in humans. The work suggests that someday researchers may be able to develop ways to maintain fertility in humans, allowing women who want to delay having children to preserve that capacity and extend their reproduction, and to prevent maternal age-related birth defects.

25 Oct 2010

New research center to study effects of BPA, phthalates on children

A new research center based at the University of Illinois will investigate whether regular exposure to bisphenol A and phthalates - chemicals widely used in plastics and other consumer products - can alter infant and adolescent development, cognition or behavior.

22 Oct 2010

CRN reinforces importance of DHA before, during and after pregnancy

In response to a study regarding fish oil use during pregnancy published in the October 19 issue of the Journal of the American Medical Association (JAMA), the Council for Responsible Nutrition (CRN), the leading trade association for the dietary supplement industry, reminds pregnant and lactating women of the undisputed importance of consuming the recommended amounts of docosahexaenoic acid (DHA) throughout pregnancy.

20 Oct 2010

Novel bioelectric signals can cause stem cells to trigger melanoma-like growth in pigment cells

Biologists at Tufts University School of Arts and Sciences have discovered that a change in membrane voltage in newly identified "instructor cells" can cause stem cells' descendants to trigger melanoma-like growth in pigment cells. The Tufts team also found that this metastatic transformation is due to changes in serotonin transport. The discovery could aid in the prevention and treatment of diseases like cancer and vitiligo as well as birth defects.

19 Oct 2010

Heavy drinking during pregnancy associated with serious developmental defects in fetus

Scientific data continue to indicate that higher intake of alcohol during pregnancy adversely affects the fetus, and could lead to very severe developmental or other problems in the child. However, most recent publications show little or no effects of occasional or light drinking by the mother during pregnancy.

15 Oct 2010

OTIS urges pregnant women to get vaccinated against influenza

The Organization of Teratology Information Specialists (OTIS), a non-profit organization based at the University of California, San Diego with affiliates across North America, urges pregnant women to receive the influenza vaccine as soon as possible. The recommendation comes shortly after the American College of Obstetricians and Gynecologists Committee on Obstetric Practice issued new guidelines regarding the influenza vaccine during pregnancy.

15 Oct 2010

PlastiPure awarded NIH and NSF grants to develop EA-Free material and products

PlastiPure, a safe plastics technology company, announced today that it has received two grants from the National Institute of Environmental Health and Safety (NIEHS), a division of the NIH, and an additional grant from the National Science Foundation (NSF). Collectively the grants fund formulation of a replacement for polycarbonate that is free of estrogenic activity (EA-Free), creating flexible food packaging that contains no EA, and developing a verifiably EA-Free baby bottle.

12 Oct 2010

Folic acid supplement does not reduce cardiovascular events, cancer or death

Use of folic acid supplements appears to lower blood levels of the amino acid homocysteine—theorized to be a risk factor for heart and blood vessel disease—but does not appear to be associated with reduced rates of cardiovascular events, cancer or death over a five-year period, according to a meta-analysis of previously published studies in the October 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

12 Oct 2010

PlastiPure, ReliaBrand partner to produce EA-Free plastic consumer products

PlastiPure, a safer-plastics technology company, has announced a partnership with ReliaBrand to license infant feeding, sports bottle, food packaging, and medical products free of harmful chemicals that cause estrogenic activity (EA). Chemicals with EA have been strongly linked to adverse health effects such as birth defects, reproductive cancers, and behavioral and learning disorders. The widely known chemicals BPA and phthalates are only a few of thousands of chemicals suspected to have EA.

11 Oct 2010