Immune System News and Research

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Pre-existing CMV immunity protects mothers and babies from transmission and birth defects

Researchers at Tulane University have shown for the first time that mothers are much less likely to transmit a common virus known to cause miscarriages and birth defects if they are exposed to the virus prior to becoming pregnant.

6 Oct 2023

USC-led team develops vaccine to boost immune system against superbugs

What if a vaccine, given to patients just before or after arriving at the hospital, could protect them against lethal superbugs that lurk in healthcare settings?

5 Oct 2023

Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

Researchers at Vanderbilt-Ingram Cancer Center have discovered a druggable target on natural killer cells that could potentially trigger a therapeutic response in patients with immunotherapy-resistant, triple-negative breast cancer.

5 Oct 2023

New insights into how neutrophils fight Candida albicans infection

Umeå University researchers, Sweden, unveil how the most common white blood cells, neutrophils, counter Candida albicans toxin stopping its tracks.

5 Oct 2023

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Challenges associated with the development and design of neoantigen cancer vaccines.

5 Oct 2023

New zebrafish xenograft platform could help screen for glioblastoma treatments

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study by the Gerhardt and De Smet labs published in EMBO Molecular Medicine.

4 Oct 2023

Study identifies potential new way to protect premature babies from deadly infection

Premature babies in neonatal care units are extremely vulnerable, and susceptible to life-threatening infections.

4 Oct 2023

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

The connection between the CHD gene and autism-related gastrointestinal (GI) manifestations.

4 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

Stem cell-derived islet cell therapy shows promise for type 1 diabetes

Six adults with type 1 diabetes (T1D) treated with stem cell-derived islet cells (VX-880) have shown improved blood sugar control with three participants achieving insulin independence, according to new research being presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Hamburg (2-6 Oct).

3 Oct 2023

Research opens the door for better use of people's own immune system T cells to fight cancer

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

3 Oct 2023

IU cancer researcher receives NCI grant to examine how immune cells support breast cancer development

A breast cancer researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center received a five-year, $2.2 million grant from the National Cancer Institute to examine how certain immune cells support metastatic breast cancer development-;and how to stop it.

3 Oct 2023

Start Codon invites life sciences leaders, founders, and investors to Innovation Showcase 2023

Start Codon is pleased to invite life sciences people from across the life science and biotech industries to attend their Innovation Showcase 2023.

From Start Codon Ltd 2 Oct 2023

Killer T cells in older adults found to be less effective at fighting influenza viruses

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells – a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups.

30 Sep 2023

Wildling mice provide insights into how microbes affect allergies

The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis.

29 Sep 2023

Study reveals new insights into how the immune system prevents autoimmunity

Researchers at Stanford University School of Medicine, Yale University School of Medicine, and the Hospital for Special Surgery Research Institute have uncovered new details about how the immune system prevents the production of antibodies that can recognize and damage the body's own, healthy tissues.

29 Sep 2023

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

29 Sep 2023

New research reveals how social isolation impacts behavior and lifespan in social species

Researchers used Camponotus fellah (carpenter ants) as a model species to perform behavioral tracking and ribonucleic acid-sequencing (RNA-seq) to study the transcriptome-level differences between socially isolated workers versus workers in groups.

29 Sep 2023

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Researchers from the University of Texas Southwestern have developed an aerosolized, mutated form of ACE2 that effectively neutralizes various SARS-CoV-2 variants in both cell cultures and mice. The study suggests that this modified ACE2 has promising preventive and therapeutic potential against COVID-19, especially with its easy aerosolized administration.

28 Sep 2023

Neoadjuvant immunotherapy shows promise in multiple cancer types

Treating cancer with immunotherapies known as an immune checkpoint blockade (ICB) prior to surgery (so-called neoadjuvant immunotherapy) has been a rapidly growing area of research, but the scientific community is just scratching the surface of what is possible, according to a review article co-authored by several current and former investigators from the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Kimmel Cancer Center.

28 Sep 2023

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Immune System News and Research

Pre-existing CMV immunity protects mothers and babies from transmission and birth defects

USC-led team develops vaccine to boost immune system against superbugs

Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

New insights into how neutrophils fight Candida albicans infection

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

New zebrafish xenograft platform could help screen for glioblastoma treatments

Study identifies potential new way to protect premature babies from deadly infection

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

Could infants' robust immune responses reshape future vaccination strategies?

Stem cell-derived islet cell therapy shows promise for type 1 diabetes

Research opens the door for better use of people's own immune system T cells to fight cancer

IU cancer researcher receives NCI grant to examine how immune cells support breast cancer development

Start Codon invites life sciences leaders, founders, and investors to Innovation Showcase 2023

Killer T cells in older adults found to be less effective at fighting influenza viruses

Wildling mice provide insights into how microbes affect allergies

Study reveals new insights into how the immune system prevents autoimmunity

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

New research reveals how social isolation impacts behavior and lifespan in social species

Aerosolized ACE2 neutralizes COVID-19 variants in lab and mice tests

Neoadjuvant immunotherapy shows promise in multiple cancer types

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