Lungs News and Research

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Preterm C-section could raise risk of breathing difficulties: Study

Cesarean sections are often performed when a baby is going to be born early. Labor may also be induced when a woman's water breaks too early in the pregnancy. However, two new studies suggest that these common practices may, in fact, not benefit babies. The two new studies were presented Thursday at the annual meeting of the Society for Maternal-Fetal Medicine.

12 Feb 2012

Human 'shock absorbers' discovered

An international team of scientists, led by the University of Sydney, has found the molecular structure in the body which functions as our “shock absorber”. The discovery of the previously unknown part of the molecule will be applied to the researchers’ work on designing improved versions of a human blood vessel and on repairing skin damage, including burns.

12 Feb 2012

UofL to receive Grand Challenges tuberculosis biomarkers grant

The University of Louisville announced today that it will receive a tuberculosis (TB) biomarkers grant through the Bill & Melinda Gates Foundation's Grand Challenges in Global Health program, an initiative which seeks to overcome persistent bottlenecks in creating new tools that can radically improve health in the developing world. James E. Graham, Ph.D., associate professor of microbiology and immunology at the UofL School of Medicine, will pursue an innovative research project to identify and validate TB biomarkers, titled "Disposable Sampling Plate and Breath Test to Identify Patients with Active Tuberculosis."

10 Feb 2012

IKBKE protein plays two roles in tobacco-related NSCLC

Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce IKBKE and, in turn, IKBKE induces chemotherapy resistance.

10 Feb 2012

LFA seeks grant applications to address important areas of lupus research

The Lupus Foundation of America (LFA) seeks grant applications to advance the science and medicine of lupus and to help improve the quality of lives of all people affected by this disease. The LFA is seeking grant applications to address the following areas of lupus research: cutaneous (skin) lupus, pediatric lupus, adult stem cell transplantation, and neuropsychiatric lupus, which affects the brain and nervous system.

10 Feb 2012

Cancer-related fatigue linked to muscle mass and strength

Many patients with advanced cancer suffer from cachexia, a condition also called body-wasting or wasting syndrome, which causes significant weight loss, extreme fatigue and reduces quality of life.

10 Feb 2012

Two new cancer research laboratories at WEHI receive $2M ACRF funding

The Australian Cancer Research Foundation (ACRF) has committed $2 million towards the fit-out of two new cancer research laboratories at the Walter and Eliza Hall Institute.

9 Feb 2012

LFA announces new grants for critical areas of lupus research

Today, the Lupus Foundation of America (LFA) announced new research grants awarded to fund critical areas of research where gaps exist in the understanding and knowledge of lupus including: pediatric lupus, cutaneous (skin) lupus, mid-to-late stage translational research, adult stem cells, and neuropsychiatric lupus, which affects the brain and nervous system.

9 Feb 2012

Link between coronary artery disease and prostate cancer

In a large analysis of men participating in a prostate drug trial, researchers at the Duke Cancer Institute found a significant correlation between coronary artery disease and prostate cancer, suggesting the two conditions may have shared causes.

8 Feb 2012

Center for LAM Research and Clinical Care at BWH to conduct phase I combination drug trial

The Center for LAM Research and Clinical Care at Brigham and Women's Hospital (BWH) has been awarded a $1 million plus, four-year grant from the U.S. Department of Defense Office of the Congressionally Directed Medical Research Programs to fund their work on lymphangioleiomyomatosis.

8 Feb 2012

Elevated risk of PE occurs within first 7 days after total joint replacement surgery

The elevated risk of pulmonary embolism (PE) - a blood clot that travels from the leg to the lungs - following total joint replacement (TJR) surgery has been well established, yet little is known about the natural course and timing of this potentially fatal condition.

8 Feb 2012

Researchers discover function and expression of CD97 in malignant gliomas

Researchers at Virginia Commonwealth University Medical Center's VCU Massey Cancer Center and Harold F. Young Neurosurgical Center and Old Dominion University have discovered that suppression of Wilms tumor 1 protein (WT1) results in downregulation of CD97 gene expression in three glioblastoma cell lines and reduces the characteristic invasiveness exhibited by glial tumor cells.

8 Feb 2012

Anticoagulation drugs can prevent PE, DVT after total joint replacement

Following a total joint replacement, anticoagulation (blood thinning) drugs can prevent Deep Vein Thrombosis (DVT), a blood clot deep within the extremities, or a pulmonary embolism (PE), a complication that causes a blood clot to move to the lungs.

7 Feb 2012

Smoking leads to early cognitive decline: Study

There is growing evidence that using cigarettes can also affect the brain: the latest study shows that smoking is associated with cognitive decline as early as age 45, and that male smokers may be more vulnerable to these mental effects than women.

7 Feb 2012

New guidelines for travellers to avoid DVT on long flights

New guidelines for travellers have been issued. Experts warn that those with a higher risk of serious blood clots who opt for the window seat on flights longer than four hours are potentially putting themselves in danger. People who should be most concerned are those who have recently had surgery, cancer patients, those with limited mobility, the severely obese, and travellers over 70. However, healthy women on the pill and those who are pregnant should also be careful, according to the guidelines by the American College of Chest Physicians.

7 Feb 2012

Asthmatic mothers encouraged to breastfeed without fear as it boosts baby’s lung power: Study

In their study published in the American Journal of Respiratory and Critical Care Medicine they looked at nearly 1,500 children from birth to ages eight to 14. Parents provided information on breastfeeding history when their children were 12 months old, and the children had a series of tests to assess lung function between the ages of 8 and 14.

7 Feb 2012

Clinical Cancer Research publishes results of Aduro's ANZ-100 and CRS-207 Phase 1 studies

Aduro BioTech, Inc. is pleased to announce the publication of two therapeutic cancer vaccine Phase 1 studies in Clinical Cancer Research. In the article, which was featured as one of the highlights of the issue, Dr. Dung Le et al. reported that intravenous administration of ANZ-100 and CRS-207 was well tolerated in subjects with advanced, treatment-refractory cancers.

7 Feb 2012

Cyclin D1 oncogene may promote chromosomal instability

A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of Cancer Biology, have shown in a study published online Feb. 6 in the Journal of Clinical Investigation that the oncogene cyclin D1 may promote a genetic breakdown known as chromosomal instability (CIN). CIN is a known, yet poorly understood culprit in tumor progression.

7 Feb 2012

Vitrolife fourth quarter sales increase 18% to SEK 95 million

Vitrolife AB: Fourth quarter - Sales increased by 19 percent in local currency. Sales were the highest ever for a single quarter and amounted to SEK 95 (81) million, corresponding to an increase of 18 percent in SEK.

7 Feb 2012

New ACCP guidelines address DVT/PE risk factors for long-distance travel

New evidence-based guidelines from the American College of Chest Physicians (ACCP) address the many risk factors for developing a deep vein thrombosis (DVT), or blood clot, as the result of long-distance travel.

7 Feb 2012