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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Scientists identify RingoA protein as key regulator of meiosis

Published today in Nature Communications, a study by scientists at the Institute for Research in Biomedicine headed by ICREA researcher Angel R. Nebreda has reported that the protein RingoA is a key regulator of meiosis--the cell division process that gives rise to ovules and sperm for sexual reproduction in mammals.

31 Mar 2016

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

While childhood cancer is rare (adult malignancies after 20 years are 20-30 times more common in general) it remains a major cause of death by disease in children. 15,700 children are diagnosed with cancer each year in the USA.

31 Mar 2016

Researchers uncover new clue that may help fight AML

A study led by researchers from the Cancer Science Institute of Singapore at the National University of Singapore has uncovered a new clue that may help fight acute myeloid leukaemia (AML), the most common form of cancer of the blood and bone marrow, and an aggressive type of cancer. The findings open a new door to treating the disease more effectively.

30 Mar 2016

Versatile Automated Microplate Sample Screening Applications

In this interview, News Medical speaks Tobias Pusterla, Ph.D from BMG Labtech about versatile automated microplate sample screening applications.

From BMG LABTECH GmbH 30 Mar 2016

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Scientists have devised a triple-stage "cluster bomb" system for delivering the chemotherapy drug cisplatin, via tiny nanoparticles designed to break up when they reach a tumor.

30 Mar 2016

Researchers use novel technology to sequence Y chromosome in malaria spreading mosquitoes

A team of researchers with the Fralin Life Science Institute at Virginia Tech, working with a large international consortium, has sequenced the Y chromosome--the genetic driver of sex-determination and male fertility-- in a family of malaria spreading mosquitoes.

29 Mar 2016

New approach allows noninvasive identification of tumor mutations in lung cancer patients

Researchers at the Stanford University School of Medicine have devised a way to significantly increase the sensitivity of a technique to identify and sequence DNA from cancer cells circulating in a person's blood.

29 Mar 2016

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?

29 Mar 2016

Shugoshin protein maintains proper gene expression in subtelomeres

A research group discovered a new function of the chromosomal terminus, which may lead to the clarification of the mechanism for developing abnormal telomere structure such as multiple malformation and mental retardation.

29 Mar 2016

Promising UCLA discovery could lead to new method for improving cancer treatments

A promising new discovery by UCLA scientists could lead to a new method of identifying cancer patients that express high levels of an enzyme and are more likely to respond to cancer treatments.

29 Mar 2016

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

UT Southwestern Medical Center researchers have discovered a mutation that causes a rare systemic disorder known as X-linked reticulate pigmentary disorder (XLPDR) and, significantly, the unexpected cellular mechanism by which the mutation causes the disease.

29 Mar 2016

SLU scientist describes several tactics that can help cells overcome lesions

In a recent review paper published in Nature Structural & Molecular Biology, SLU scientist Alessandro Vindigni, Ph.D., describes the strategies cells use when their DNA faces replication stress, challenges that may derail a cell's ability to reproduce.

29 Mar 2016

Study reveals new hypothesis on evolution of hundreds of malaria species

A study published this week in the journal Molecular Phylogenetics and Evolution reveals a new hypothesis on the evolution of hundreds of species of malaria - including the form that is deadly to humans.

26 Mar 2016

DNA sequence features predict genome-wide binding pattern of key protein involved in brain disorders

Researchers from the University of Illinois at Urbana-Champaign and the University of California-Davis are combining in vivo experimentation with computation for highly accurate prediction of the genome-wide binding pattern of a key protein involved in brain disorders.

25 Mar 2016

Personalized medicine promises better treatment options for cystic fibrosis patients

For a highly variable disease like cystic fibrosis, personalized medicine promises treatments based on individual factors, down to the molecular level. This promise is especially alluring for the treatment of children with cystic fibrosis, who are at particular risk for complications that could affect them throughout their lives.

25 Mar 2016

Self-repairing cancer cells: A new pathway for cancer treatment

With narrow bodies and no collarbones, mice are able to squeeze through holes as small as a quarter-inch in diameter. Cancer cells similarly are able to migrate through extremely tight quarters but with a major difference: The journey often comes at a price - the deformation and, in some cases, rupture of the outer lining of a cell's nucleus. While deformation and rupture can sometimes lead to cell death, the cell - about 90 percent of the time - also has the ability to repair itself.

25 Mar 2016

Common genetic defect in beta cells may underlie both known forms of diabetes

New research by Dr. Sylvie Lesage, scientist at Maisonneuve-Rosemont Hospital and associate research Professor at University of Montreal, just published in the prestigious international scientific journal Nature Genetics, has discovered that a common genetic defect in beta cells may underlie both known forms of diabetes.

25 Mar 2016

Scientists unravel genetic basis of autism spectrum disorder

The types of gene mutations that contribute to autism are more diverse than previously thought, report researchers at University of California, San Diego School of Medicine in the March 24 online issue of The American Journal of Human Genetics. The findings, they say, represent a significant advance in efforts to unravel the genetic basis of autism spectrum disorder (ASD).

25 Mar 2016

SGO acting on ovarian cancer report recommendations

During the Society of Gynecologic Oncology’s 47th Annual Meeting on Women’s Cancer today, SGO convened a panel of ovarian cancer experts to discuss the recently released report by the National Academy of Medicine (NAM),

24 Mar 2016

Genetic testing in women with ovarian cancer helps determine prognosis

A study examining mutations in DNA repair genes in women with advanced ovarian cancer found that the disease remained at bay longer in women with the mutations than without, and that women having cancers with these mutations lived longer.

24 Mar 2016

DNA News and Research

Further Reading

Scientists identify RingoA protein as key regulator of meiosis

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

Researchers uncover new clue that may help fight AML

Versatile Automated Microplate Sample Screening Applications

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Researchers use novel technology to sequence Y chromosome in malaria spreading mosquitoes

New approach allows noninvasive identification of tumor mutations in lung cancer patients

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

Shugoshin protein maintains proper gene expression in subtelomeres

Promising UCLA discovery could lead to new method for improving cancer treatments

UT Southwestern scientists discover mutation that causes X-linked reticulate pigmentary disorder

SLU scientist describes several tactics that can help cells overcome lesions

Study reveals new hypothesis on evolution of hundreds of malaria species

DNA sequence features predict genome-wide binding pattern of key protein involved in brain disorders

Personalized medicine promises better treatment options for cystic fibrosis patients

Self-repairing cancer cells: A new pathway for cancer treatment

Common genetic defect in beta cells may underlie both known forms of diabetes

Scientists unravel genetic basis of autism spectrum disorder

SGO acting on ovarian cancer report recommendations

Genetic testing in women with ovarian cancer helps determine prognosis

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