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VS120 – fast and precise fluorescence slide scanning

Olympus’ award winning VS120 virtual slide systems have been updated to enable precision and accuracy in high-speed fluorescence and brightfield scanning – with the ability to scan a brightfield slide in under two minutes.

From Evident Corporation - Life Sciences 11 Mar 2015

Research findings offer new insights into pathophysiology of PTSD

Researchers at the Veterans Affairs San Diego Healthcare System and University of California, San Diego School of Medicine, with colleagues in New York and the United Kingdom, have identified genetic markers, derived from blood samples that are linked to post-traumatic stress disorder (PTSD). The markers are associated with gene networks that regulate innate immune function and interferon signaling.

11 Mar 2015

Developments in ChIP technology

Biowales, one of the UK’s leading events for the life sciences sector, this year will focus on the life sciences supply chain providing practical commercial opportunities for growth through novel routes to market in the private sector and National Health Service (NHS).

From Chromatrap® - Porvair Sciences Ltd 24 Feb 2015

Epigenetics and women’s health research: an interview with Professor Steve Conlan, Swansea University

Our research into gynaecological oncology focuses around understanding mechanisms of how genes are regulated or how they become dysregulated in a disease; and also the effects that has on the surface of the endometrium and also the function of the ovaries...

From Chromatrap® - Porvair Sciences Ltd 24 Feb 2015

Ready to reconstitute BPW adds convenient option to support high throughput Salmonella testing in chocolate production

The discovery of Salmonella in one batch of a particular chocolate product, which prompted a recent recall, is a reminder of the importance of this pathogen in confectionery products.

20 Feb 2015

UT Arlington chemist receives NIH's Academic Research Enhancement Award for protein research

A University of Texas at Arlington bio-analytical chemist exploring proteins, their structures and functions by using cutting-edge analytical instrumentation called mass spectrometry has received an Academic Research Enhancement Award from the National Institutes of Health.

18 Feb 2015

TSRI scientists discover novel mechanism involved in Alzheimer's, Parkinson's and ALS

Scientists from the Florida campus of The Scripps Research Institute have for the first time discovered a killing mechanism that could underpin a range of the most intractable neurodegenerative diseases such as Alzheimer's, Parkinson's and ALS.

16 Feb 2015

Scientists find seven new genes that can cause X-linked intellectual disability

X-linked intellectual disability is a disorder that predominantly affects men and can have highly variable clinical manifestations. Scientists at the Max Planck Institute for Molecular Genetics in Berlin have found seven new genes that can cause this genetic disease: Mutations of these genes on the X chromosome lead to various forms of intellectual disability.

15 Feb 2015

AXT adds TriFoil imaging products to their preclinical imaging portfolio

TriFoils flagship is the Triumph tri-modal imaging system that incorporates PET/SPECT and CT technologies all in a single instrument. It has a bore size of 15cm and an axial view of 30cm making ideal for small animal studies.

From MR Solutions 13 Feb 2015

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

The new study, published recently in the journal Brain, revealed the mechanism of toxicity of a misfolded form of the protein that underlies prion diseases, such as bovine spongiform encephalopathy (“mad cow disease”) and its human equivalent, Creutzfeldt-Jakob disease.

13 Feb 2015

Researchers develop novel approach to identify potential antimalarial drugs

Each year nearly 600,000 people--mostly children under age five and pregnant women in sub-Saharan Africa--die from malaria, caused by single-celled parasites that grow inside red blood cells. The most deadly malarial species--Plasmodium falciparum--has proven notoriously resistant to treatment efforts.

12 Feb 2015

PBI announces receipt of first purchase order for new Barozyme HT48 High-throughput System

Pressure BioSciences, Inc., a leader in the development and sale of broadly enabling sample preparation solutions using pressure cycling technology ("PCT")-based instruments and consumables to the worldwide life sciences industry, today announced the receipt of the first purchase order for its new Barozyme HT48 High-throughput System.

10 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Researchers develop quality assurance tool for genome editing

A research team at Boston Children's Hospital's Program in Cellular and Molecular Medicine has developed a quality assurance tool for scientists using genome-editing technologies like the increasingly popular CRISPR. The assay, called high throughput genome translocation sequencing (HTGTS), rapidly gauges—for any given gene—these technologies' accuracy and their risk for causing potentially dangerous genomic collateral damage.

9 Feb 2015

Gramicidin-Based Fluorescence Assay can help predict drug toxicity

Sometimes, toxic side effects aren't discovered until fairly late in the drug development process, when substantial amounts of time and money have already been invested in clinical trials.

9 Feb 2015

New RT-DC technology enables faster and continuous mechanical screening of cells

Cells, like any other material, have mechanical properties that can serve for their characterization. For example, cancer cells are characteristically more deformable than healthy cells.

9 Feb 2015

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

There are two types of thyroid cells and therefore there are two broad types of thyroid cancer. Medullary carcinoma is derived from parafollicular or C cells, whereas follicular cells give rise to several types of thyroid cancers.

4 Feb 2015

OGT study explores successful adoption of CytoSure ISCA array at Sheffield Children's NHS Foundation Trust

Oxford Gene Technology, The Molecular Genetics Company, explores how Sheffield Children's NHS Foundation Trust has seamlessly transferred to its CytoSure ISCA 8x60k platform, in a new case study entitled Evaluating and switching to CytoSure microarrays. As the result of a highly stringent National Health Service tender for the supply of oligo-based cytogenetics research arrays, CytoSure was selected based on the quality of data and analysis software.

From Oxford Gene Technology 4 Feb 2015

Productive Pipetting - Are Robots the Solution?

An interview with Juerg Bass from Integra Biosciences, discussing the advantages and disadvantages of laboratory robots.

From INTEGRA Biosciences 3 Feb 2015

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Antibiotic-resistant infections are on the rise, foiling efforts to reduce death rates in developing countries where uncontrolled use of antibiotics and poor sanitation run amok. The epidemic of "superbugs," bacteria resistant to antibiotics, knows no borders -- presenting a clear and present danger around the globe.

31 Jan 2015

High Throughput News and Research

VS120 – fast and precise fluorescence slide scanning

Research findings offer new insights into pathophysiology of PTSD

Developments in ChIP technology

Epigenetics and women’s health research: an interview with Professor Steve Conlan, Swansea University

Ready to reconstitute BPW adds convenient option to support high throughput Salmonella testing in chocolate production

UT Arlington chemist receives NIH's Academic Research Enhancement Award for protein research

TSRI scientists discover novel mechanism involved in Alzheimer's, Parkinson's and ALS

Scientists find seven new genes that can cause X-linked intellectual disability

AXT adds TriFoil imaging products to their preclinical imaging portfolio

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

Researchers develop novel approach to identify potential antimalarial drugs

PBI announces receipt of first purchase order for new Barozyme HT48 High-throughput System

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Researchers develop quality assurance tool for genome editing

Gramicidin-Based Fluorescence Assay can help predict drug toxicity

New RT-DC technology enables faster and continuous mechanical screening of cells

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

OGT study explores successful adoption of CytoSure ISCA array at Sheffield Children's NHS Foundation Trust

Productive Pipetting - Are Robots the Solution?

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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