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Strong link between high HuR protein levels and malignancy of HCC

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation.

27 Jan 2012

Boehringer Ingelheim initiates two afatinib phase III trials in head and neck cancer

Boehringer Ingelheim announced today the initiation of two phase III clinical trials, LUX-Head & Neck 1 and LUX-Head & Neck 2. These trials evaluate afatinib in patients with metastatic and recurrent head and neck cancer, and in patients with locally advanced disease, respectively.

27 Jan 2012

Lansoprazole increases risk of sore throats, respiratory problems in children with asthma

Adding the acid reflux drug lansoprazole to a standard inhaled steroid treatment for asthma does not improve asthma control in children who have no symptom of acid reflux, according to a new study funded in part by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health. Lansoprazole therapy slightly increased the risk of sore throats and other respiratory problems in children, however.

25 Jan 2012

HHMI honors EMBL Monterotondo researcher with International Early Career Scientist award

Rocio Sotillo, a staff scientist at the European Molecular Biology Laboratory (EMBL) in Monterotondo, is one of 28 outstanding young biomedical scientists who have been honoured with a Howard Hughes Medical Institute (HHMI) International Early Career Scientist award this year.

25 Jan 2012

Lansoprazole does not control asthma in children

Asthma and gastroesophageal reflux (GER) are both common illnesses in children. GER in children often occurs without the typical symptoms of heartburn, and physicians frequently prescribe the acid reflux drug lansoprazole to supplement the standard inhaled steroid treatment for children with uncontrolled asthma regardless of GER symptoms.

25 Jan 2012

Novel detection of ovarian cancer in early stages

Ovarian cancer is often detected at a late stage and it is the leading cause of death due to gynecological cancers, and the sixth leading cause of cancer death in women. According to latest discovery by researchers at Sydney’s Garvan Institute there may be a way this killer cancer is detected earlier.

24 Jan 2012

Heartburn drugs ineffective in kids with asthma: Study

A drug used to treat acid reflux has often been used for hard-to-treat asthma. A new study finds that it does not help children with the breathing disease and may cause side effects.

24 Jan 2012

Positive affect, self-affirmation help patients with chronic diseases to overcome obstacles

The experience of daily positive affect -- a mild, happy feeling -- and self-affirmation helps some patients with chronic diseases, including coronary artery disease, high blood pressure and asthma, make better decisions about their health.

24 Jan 2012

Positive affirmation may help hypertensive African-Americans effectively in medication adherence

When it comes to taking prescribed medications for hypertension, a patient's self confidence could be as important as doctor's orders. A new study by researchers at NYU School of Medicine reveals that positive affirmation, when coupled with patient education, seems to help patients more effectively follow their prescribed medication regimen.

24 Jan 2012

Elevated blood lead levels put smokers at higher risk for renal cell carcinoma

Higher than normal levels of lead in the blood may signal a risk two times higher than average of developing renal cell carcinoma in smokers, according to medical researchers.

24 Jan 2012

Ikaria receives FDA orphan drug designation for use of iNO in PAH

Ikaria, Inc., a critical care company focused on developing and commercializing innovative therapies for critically ill patients, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for the use of inhaled nitric oxide (iNO) with the INOpulse DS drug-delivery system as a combination product for pulmonary arterial hypertension.

23 Jan 2012

Study provides valuable information on which cancer patients might need help to quit smoking

A new analysis has found that a substantial number of lung and colorectal cancer patients continue to smoke after being diagnosed. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study provides valuable information on which cancer patients might need help to quit smoking.

23 Jan 2012

A*STAR, GE Global Research join forces in integrated advanced medical imaging technologies

GE Global Research, the central technology development arm for GE Healthcare and all of GE's businesses, has signed a Memorandum of Understanding (MOU) with Singapore's Agency of Science, Technology and Research (A*STAR). This agreement will focus on advancing current medical imaging technologies and diagnostics to enable more accurate, earlier and faster clinical diagnoses of cancer and other diseases. The partnership between A*STAR and GE Global Research brings together two world-class research institutions, integrating their deep domain expertise in biomedical, science, and engineering capabilities to support this effort.

22 Jan 2012

First genome-wide study of high-altitude adaptations in Ethiopians

Over many generations, people living in the high-altitude regions of the Andes or on the Tibetan Plateau have adapted to life in low-oxygen conditions. Living with such a distinct and powerful selective pressure has made these populations a textbook example of evolution in action, but exactly how their genes convey a survival advantage remains an open question. Now, a University of Pennsylvania team has made new inroads to answering this question with the first genome-wide study of high-altitude adaptations within the third major population to possess them: the Amhara people of the Ethiopian Highlands.

21 Jan 2012

UHCMC now offers HITEC for women with gynecologic cancers

Patients with gynecologic cancer have new hope in a novel technology now offered at the Seidman Cancer Center at University Hospitals (UH) Case Medical Center. A team of cancer specialists, led by Robert DeBernardo, MD, is among the first in the nation to launch a dedicated program using Hyperthermic Intraperitoneal Chemotherapy (HIPEC) to treat ovarian, endometrial and select other cancers.

21 Jan 2012

Awake ECMO may be an effective bridging strategy for lung transplantation candidates

Extracorporeal membrane oxygenation (ECMO) support in awake, non-intubated patients may be an effective strategy for bridging patients to lung transplantation, according to a new study from Germany.

21 Jan 2012

Retail pork products in the U.S. have higher prevalence of MRSA bacteria

Retail pork products in the U.S. have a higher prevalence of methicillin-resistant Staphylococcus aureus bacteria (MRSA) than previously identified, according to new research by the University of Iowa College of Public Health and the Institute for Agriculture and Trade Policy.

20 Jan 2012

Technological breakthrough allows U-M Health System to reduce patients' radiation exposure

A technological breakthrough is allowing the University of Michigan Health System to be the first teaching hospital in the U.S. to perform some CT scans using a fraction of the radiation dose required for a conventional CT image.

20 Jan 2012

Combination of gefitinib and miRNA-inhibitor might effectively treat NSCLC

New research published in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs.

20 Jan 2012

Lung association criticizes state tobacco policies

Anti-tobacco efforts by U.S. states were "abysmal" last year as their collective spending on anti-smoking programs declined 11 percent and only two raised cigarette taxes, the American Lung Association said. While more than half the states already ban the use of cigarettes in restaurants, bars and workplaces, no additional states passed comprehensive anti-smoking laws last year, the Washington-based health advocacy group said today in a report.

20 Jan 2012

Lungs News and Research

Strong link between high HuR protein levels and malignancy of HCC

Boehringer Ingelheim initiates two afatinib phase III trials in head and neck cancer

Lansoprazole increases risk of sore throats, respiratory problems in children with asthma

HHMI honors EMBL Monterotondo researcher with International Early Career Scientist award

Lansoprazole does not control asthma in children

Novel detection of ovarian cancer in early stages

Heartburn drugs ineffective in kids with asthma: Study

Positive affect, self-affirmation help patients with chronic diseases to overcome obstacles

Positive affirmation may help hypertensive African-Americans effectively in medication adherence

Elevated blood lead levels put smokers at higher risk for renal cell carcinoma

Ikaria receives FDA orphan drug designation for use of iNO in PAH

Study provides valuable information on which cancer patients might need help to quit smoking

A*STAR, GE Global Research join forces in integrated advanced medical imaging technologies

First genome-wide study of high-altitude adaptations in Ethiopians

UHCMC now offers HITEC for women with gynecologic cancers

Awake ECMO may be an effective bridging strategy for lung transplantation candidates

Retail pork products in the U.S. have higher prevalence of MRSA bacteria

Technological breakthrough allows U-M Health System to reduce patients' radiation exposure

Combination of gefitinib and miRNA-inhibitor might effectively treat NSCLC

Lung association criticizes state tobacco policies

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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