Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Scientists link undiagnosed human disease with rare mutation in PHETA1 gene

Virginia Tech scientists with the Fralin Biomedical Research Institute at VTC have manipulated genes to link an undiagnosed human disease with a rare mutation in the PHETA1 gene.

30 Apr 2020

FMT improves clinical outcomes in extremely ill patients with drug-resistant bacteria

Transferring fecal matter from the digestive systems of healthy donors to extremely ill patients who had previously been infected with drug-resistant bacteria resulted in shorter hospital stays, fewer bloodstream infections and infections that were easier to treat, according to research that was selected for presentation at Digestive Disease Week 2020.

30 Apr 2020

Innovative approach offers kidney-sparing treatment option for upper tract urothelial cancer

Treatment of low-grade upper tract urothelial cancer usually involves radical surgery to remove the kidney and ureter, highlighting the need for improved treatments.

30 Apr 2020

ACE inhibitors appear to be safe and beneficial for COVID-19, say researchers

Researchers in India have conducted a meta-analysis investigating the effects of using angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) on outcomes among patients with COVID-19.

29 Apr 2020

Breakthrough study shows liquid biopsy test can safely detect 26 undiagnosed cancers

Results from a first-of-its-kind study of a multicancer blood test in more than 9,900 women with no evidence or history of cancer showed the liquid biopsy test safely detected 26 undiagnosed cancers, enabling potentially curative treatment.

29 Apr 2020

Study examines temperature increases in U.S. counties and their impact on crop yield

The global pandemic has put a focus on essential workers, those we rely on for basic services. Workers who pick crops, from strawberries to apples to nuts, already face harsh conditions harvesting in fields during summer harvest months.

29 Apr 2020

How toxic are chloroquine and hydroxychloroquine to cells?

The spread of the pandemic disease COVID-19 caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has now reached almost every country of the world, with over 3.11 million cases and over 217,000 deaths as of April 29, 2020.

29 Apr 2020

Men are twice more likely to die of COVID-19 than women

There have been studies that have revealed that men are more likely to get more severe symptoms from COVID-19 disease and also more likely to die from complications of the disease. A new study corroborates these findings. The study titled, “Gender differences in patients with COVID-19: Focus on severity and mortality,” is published in the latest issue of the journal Frontiers in Public Health.

29 Apr 2020

Coronavirus may cause sudden stroke in younger patients, doctors warn

Older adults and those with underlying medical conditions are at risk of experiencing severe coronavirus disease (COVID-19). Younger people appeared to experience only mild illness, but doctors warn that the viral infection may cause sudden strokes.

23 Apr 2020

1.7 billion people at higher risk from COVID-19, study says

The COVID-19 pandemic affecting 185 countries and territories the world over has already claimed over 190,000 lives and sickened well over 2.7 million as of April 24, 2020. Research shows that most of these fatalities are in older people or those who have underlying medical conditions.

23 Apr 2020

Is the confidence in hydroxychloroquine for the management of COVID-19 justified?

A new review paper published in the preprint open-access journal medRxiv in April 2020 reports that there is not enough evidence to justify the widespread use of the drug hydroxychloroquine (HCQ) in the treatment or prophylaxis of the current COVID-19 illness.

23 Apr 2020

RAS inhibitors and COVID-19 severity in hypertensive patients

A new study published in the journal JAMA Cardiology in April 2020 reports that patients with hypertension who are taking medications called ACE inhibitors (ACEI) or ARBs are not at higher risk for death or more severe illness with COVID-19. This conclusion supports current guidelines for the treatment of hypertension during this pandemic.

23 Apr 2020

Study identifies key nose cells as likely COVID-19 virus entry points

Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells.

23 Apr 2020

A faster and easier treatment option to prevent blindness in preterm infants

Babies born prematurely who require treatment to prevent blindness from retinopathy of prematurity (ROP) could be treated with a dose of Avastin (bevacizumab) that is a fraction of the dose commonly used for ROP currently.

23 Apr 2020

Breakthrough discovery in HIV research opens path to new, better therapies

New research on the human immunodeficiency virus (HIV) structure has revealed a promising novel drug target for treating it.

23 Apr 2020

Salt substitution could prevent nearly half a million cardiovascular deaths in China

A nationwide intervention to replace regular household salt with potassium-enriched salt substitutes in China could prevent nearly half a million cardiovascular deaths per year, according to a new modelling study published in the British Medical Journal.

22 Apr 2020

The other COVID risks: How race, income, zip code influence who lives or dies

It started with a headache in late March. Then came the body aches.

22 Apr 2020

Exploring how to maximize diagnostic accuracy of swallow study while minimizing risk

More than half a million children are diagnosed with swallowing problems each year. The gold standard for diagnosing swallowing problems is the videofluoroscopic swallow study, also known as the modified barium swallow study.

21 Apr 2020

Immunity to coronavirus infection may help stem the pandemic

The raging coronavirus pandemic is causing immense fear and uncertainty across the world. One of the most distressing aspects of COVID-19 disease is the seemingly large number of unknowns. These include the burning question of immunity. Does a person who was sick with the COVID-19 and then recovered or was infected without symptoms, have immunity against re-infection?

21 Apr 2020

Machine learning helps researchers to distinguish a rare subtype of kidney cancer

Putting together research for publication can be a challenging and time-consuming process, heightened even further because of the current COVID-19 situation, during which non-essential labs have been hibernated and many researchers are now working separately and remotely, instead of collaborating within the same space.

21 Apr 2020

Nephrology News and Research

Further Reading

Scientists link undiagnosed human disease with rare mutation in PHETA1 gene

FMT improves clinical outcomes in extremely ill patients with drug-resistant bacteria

Innovative approach offers kidney-sparing treatment option for upper tract urothelial cancer

ACE inhibitors appear to be safe and beneficial for COVID-19, say researchers

Breakthrough study shows liquid biopsy test can safely detect 26 undiagnosed cancers

Study examines temperature increases in U.S. counties and their impact on crop yield

How toxic are chloroquine and hydroxychloroquine to cells?

Men are twice more likely to die of COVID-19 than women

Coronavirus may cause sudden stroke in younger patients, doctors warn

1.7 billion people at higher risk from COVID-19, study says

Is the confidence in hydroxychloroquine for the management of COVID-19 justified?

RAS inhibitors and COVID-19 severity in hypertensive patients

Study identifies key nose cells as likely COVID-19 virus entry points

A faster and easier treatment option to prevent blindness in preterm infants

Breakthrough discovery in HIV research opens path to new, better therapies

Salt substitution could prevent nearly half a million cardiovascular deaths in China

The other COVID risks: How race, income, zip code influence who lives or dies

Exploring how to maximize diagnostic accuracy of swallow study while minimizing risk

Immunity to coronavirus infection may help stem the pandemic

Machine learning helps researchers to distinguish a rare subtype of kidney cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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