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CWRU receives NHLBI grant to study sleep apnea as possible cause of AF

Case Western Reserve University School of Medicine has received a $3.8 million grant from the National Heart, Lung, and Blood Institute (NHLBI) to study sleep apnea as a possible cause of atrial fibrillation (AF), the most commonly diagnosed type of arrhythmia, or irregular heart rhythm.

22 Nov 2011

Study: Vaccine development efforts currently focus on incidence rather than mortality rates

Drug companies currently developing therapeutic cancer vaccines may be determining the cancers they target based on the number of annual cases, not the number of deaths they cause.

22 Nov 2011

Medicare will still cover Avastin for breast cancer, despite revocation of FDA approval

The FDA announced that Avastin, while still approved for other cancers, is more harmful than helpful to breast cancer patients.

22 Nov 2011

WSU receives NHLBI grant to develop new CF treatments

A Wayne State University research team led by Fei Sun, Ph.D., assistant professor of physiology in the School of Medicine, recently received a grant with an anticipated amount of nearly $1.9 million from the National Heart, Lung and Blood Institute of the National Institutes of Health to better understand how this defective protein in cystic fibrosis patients is prematurely digested.

22 Nov 2011

New 'triggered imaging' enables physicians to better target tumors during radiosurgery

A new type of "triggered imaging" technology enables University of Alabama at Birmingham physicians to better target tumors during radiosurgery and lessens the risk of injury to surrounding lung tissue.

22 Nov 2011

MedImmune, U-M to work toward new biologic options for cancer and other diseases

Leaders from the University of Michigan Medical School and MedImmune, the global biologics arm of AstraZeneca, have signed a new agreement to work together on a broad range of projects.

22 Nov 2011

Scientists search for main culprit behind Sj-gren's syndrome

Researchers want to find the main culprit behind the dry, irritated eyes, mouth, throat, skin, nose and more afflicting 1-3 percent of the population.

22 Nov 2011

Researchers identify EGFR protein as therapeutic target for Cushing disease

Cushing disease is a hormone disorder that causes a diverse array of symptoms, including fat accumulation, high blood pressure, osteoporosis, muscle wasting, and ultimately death. It is caused by a tumor in the anterior pituitary gland that results in the secretion of excess amounts of adrenocorticotropic hormone (ACTH). Treatment options are essentially limited to surgical resection. However, tumors commonly recur, meaning that new treatment options are needed.

22 Nov 2011

FDA clears TSC's OncoTrac medical imaging software

Translational Sciences Corporation (TSC) announced today that it has received FDA 510(k) clearance for commercialization of its OncoTrac medical imaging software.

22 Nov 2011

Breast cancer drug Avastin loses FDA support

According to a Food and Drug Administration (FDA) announcement last Friday, the cancer drug Avastin should not be used to treat breast cancer that has spread to other organs because it doesn't help patients enough to justify its risky side effects.

21 Nov 2011

2011 National Report Card on Lung Cancer notes significant change in grade for early detection

Today, Lung Cancer Alliance (LCA), the leading national support and advocacy voice for those at risk for or living with lung cancer, issued its annual 2011 National Report Card on Lung Cancer, an overall assessment of the nation's response to the continuing high mortality of lung cancer, the leading cause of cancer death.

21 Nov 2011

MedUni Vienna researchers discover important regulators in development of stem cells

A team of researchers at the MedUni Vienna's Institute of Medical Genetics has discovered that two genes (TSC/Tuberin and PRAS40) are extremely important regulators in the development of stem cells: if these genes are switched off, the stem cells do not develop but instead die a programmed cell death.

21 Nov 2011

Adeona to develop and commercialize DNA-based therapeutic for PAH using Intrexon technology

Adeona Pharmaceuticals, Inc., and the Human Therapeutics Division of Intrexon Corporation, announced today the formation of a global exclusive channel collaboration through which Adeona intends to develop and commercialize a DNA-based therapeutic using Intrexon's UltraVector platform and RheoSwitch Therapeutic System for the treatment of pulmonary arterial hypertension (PAH).

21 Nov 2011

Cancer Research UK initiates recruitment for Stratified Medicine Programme

Cancer Research UK has started recruiting patients for a pioneering initiative to demonstrate how genetic tests could be used within the NHS to help match cancer patients to the most appropriate treatment, while building a database of information for research into new targeted therapies.

21 Nov 2011

Two genetic rearrangements may trigger 5 to 7% of breast cancers

Researchers at the University of Michigan Comprehensive Cancer Center have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast cancers.

20 Nov 2011

Study: Metabolic syndrome biomarkers predict decline in lung function after WTC dust exposure

Metabolic syndrome biomarkers predict subsequent decline in lung function after particulate exposure, according to new research involving rescue personnel exposed to World Trade Center (WTC) dust.

19 Nov 2011

HRR1 after 6MW test is a strong predictor of clinical worsening in IPAH patients

Heart rate recovery at one minute after a six-minute walking distance (6MWD) test is highly predictive of clinical worsening and time to clinical worsening in patients with idiopathic pulmonary arterial hypertension (IPAH), according to a new study.

19 Nov 2011

Avastin drug not safe and effective for breast cancer patients: FDA Commissioner

FDA Commissioner Margaret A. Hamburg, M.D., said today she is revoking the agency's approval of the breast cancer indication for Avastin (bevacizumab) after concluding that the drug has not been shown to be safe and effective for that use.

19 Nov 2011

FDA revokes approval of Avastin for breast cancer

The commissioner of the Food and Drug Administration on Friday revoked the approval of the drug Avastin as a treatment for breast cancer, ruling in an emotional issue that pitted the hopes of some desperate patients against the statistics of clinical trials.

19 Nov 2011

Scientists identify novel gene mutation that causes glioblastoma

Scientists at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center, in collaboration with colleagues in Boston and South Korea, say they have identified a novel gene mutation that causes at least one form of glioblastoma (GBM), the most common type of malignant brain tumor.

18 Nov 2011

Lungs News and Research

CWRU receives NHLBI grant to study sleep apnea as possible cause of AF

Study: Vaccine development efforts currently focus on incidence rather than mortality rates

Medicare will still cover Avastin for breast cancer, despite revocation of FDA approval

WSU receives NHLBI grant to develop new CF treatments

New 'triggered imaging' enables physicians to better target tumors during radiosurgery

MedImmune, U-M to work toward new biologic options for cancer and other diseases

Scientists search for main culprit behind Sj-gren's syndrome

Researchers identify EGFR protein as therapeutic target for Cushing disease

FDA clears TSC's OncoTrac medical imaging software

Breast cancer drug Avastin loses FDA support

2011 National Report Card on Lung Cancer notes significant change in grade for early detection

MedUni Vienna researchers discover important regulators in development of stem cells

Adeona to develop and commercialize DNA-based therapeutic for PAH using Intrexon technology

Cancer Research UK initiates recruitment for Stratified Medicine Programme

Two genetic rearrangements may trigger 5 to 7% of breast cancers

Study: Metabolic syndrome biomarkers predict decline in lung function after WTC dust exposure

HRR1 after 6MW test is a strong predictor of clinical worsening in IPAH patients

Avastin drug not safe and effective for breast cancer patients: FDA Commissioner

FDA revokes approval of Avastin for breast cancer

Scientists identify novel gene mutation that causes glioblastoma

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