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Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly used to build drug molecules.

9 Aug 2022

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

Research led by Drs. Yuhai Zhao and Walter J Lukiw at the LSU Health New Orleans Neuroscience Center and the Departments of Cell Biology and Anatomy, Neurology and Ophthalmology, reports for the first time a pathway that begins in the gut and ends with a potent pro-inflammatory toxin in brain cells contributing to the development of Alzheimer's disease (AD).

9 Aug 2022

Simulation sessions improve the confidence, preparedness of medical students in providing care for dying patients

Simulated experience of caring for a dying patient and their family can improve the confidence and preparedness of medical students to provide such care, according to a new study by Brighton and Sussex Medical School (BSMS) published in the BMJ Journal of Supportive and Palliative Care.

9 Aug 2022

New approach for developing antiviral drugs could slow down future viral outbreaks, save lives

Just as with COVID-19, future viral outbreaks will have plenty of time to spread before a vaccine becomes available. A new approach developed at NTNU can save lives and prevent the need to shut down society.

9 Aug 2022

Researchers create the most bio-realistic and complex computer models of brain cells

Cedars-Sinai investigators have created the most bio-realistic and complex computer models of individual brain cells-; in unparalleled quantity.

9 Aug 2022

New simulator quantifies the effect of body posture and stomach motility on drug bioavailability

A common, economic, and easy method of administering drugs is orally, by swallowing a pill or capsule.

9 Aug 2022

New mathematical model of bone renewal predicts the effects of osteoporosis medications

The model, described today in eLife, may help improve outcomes for patients with postmenopausal osteoporosis and reduce the risks of side effects by helping physicians build more personalized treatment regimes.

9 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Researchers develop a potential way to tackle one of the underlying causes of asthma

A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London.

9 Aug 2022

Exposure to a synthetic “forever chemical” linked to non-viral hepatocellular carcinoma

Exposure to a synthetic chemical found widely in the environment is linked to non-viral hepatocellular carcinoma, the most common type of liver cancer, according to a new study conducted by researchers from the Keck School of Medicine of USC and published in JHEP Reports.

9 Aug 2022

BU researcher secures NIH grant to examine the impact of racism-related chronic stress on brain health

Emerging adulthood is a life period of identity exploration that is experienced by the majority of emerging adults as stressful. Black emerging adults have the added burden of racism-related chronic stress.

9 Aug 2022

UNH researchers receive $2.8 million NIH grant to develop and test social assistive robots

Researchers at the University of New Hampshire will receive a five-year grant totaling $2.8 million from the National Institutes of Health (NIH) to develop and test social assistive robots to aid in the care of individuals with Alzheimer's disease and related dementia in the comfort of their own homes.

9 Aug 2022

Study finds fewer synthetic cannabinoid poisonings in states with cannabis legalization

Synthetic cannabinoids, dangerous designer drugs known by such street names as K2, Spice or AK-47, appear to have less appeal in states that have legalized the natural form of cannabis.

9 Aug 2022

How effective is tecovirimat as a treatment against monkeypox?

A new study evaluated the use of tecovirimat for monkeypox treatment during the current outbreak.

9 Aug 2022

Combination of interventions more effective at reducing children’s symptoms of depression and anxiety

Behavioral scientists have long researched how to help children cope with extreme adversity – such as poverty or exposure to violence. Yanping Jiang, a researcher at the Rutgers Institute for Health, thinks she's found the answer in rural China.

9 Aug 2022

Novel AI tools accurately predict the role of DNA’s regulatory elements

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

9 Aug 2022

Study assesses the prevalence of gender-diverse youth in a rural region in Appalachia

Gender-diverse youth are at an increased risk of suicide and depression, according to the Centers for Disease Control and Prevention. But the prevalence of gender diversity is largely unknown-;especially in rural areas, where studies of the topic are rare.

9 Aug 2022

Experts use tools from artificial intelligence to rapidly identify substances that cause overdose deaths

An automated process based on computer algorithms that can read text from medical examiners' death certificates can substantially speed up data collection of overdose deaths – which in turn can ensure a more rapid public health response time than the system currently used, new UCLA research finds.

9 Aug 2022

Serbia's genome center monitors potential virus mutations to facilitate more effective COVID-19 control

In partnership with BGI Genomics from China, Serbia's first genome sequencing center, opened in December 2021, is monitoring potential virus mutations to facilitate more effective COVID-19 control and accelerating access to genomics to enhance health outcomes.

9 Aug 2022

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today (Tuesday).

8 Aug 2022

Medicine News and Research

Scripps, UCLA chemists develop a 'molecular editing' toolkit for modifying bicyclic aza-arenes

Research reveals a gut-brain pathway that contributes to the development of Alzheimer’s disease

Simulation sessions improve the confidence, preparedness of medical students in providing care for dying patients

New approach for developing antiviral drugs could slow down future viral outbreaks, save lives

Researchers create the most bio-realistic and complex computer models of brain cells

New simulator quantifies the effect of body posture and stomach motility on drug bioavailability

New mathematical model of bone renewal predicts the effects of osteoporosis medications

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Researchers develop a potential way to tackle one of the underlying causes of asthma

Exposure to a synthetic “forever chemical” linked to non-viral hepatocellular carcinoma

BU researcher secures NIH grant to examine the impact of racism-related chronic stress on brain health

UNH researchers receive $2.8 million NIH grant to develop and test social assistive robots

Study finds fewer synthetic cannabinoid poisonings in states with cannabis legalization

How effective is tecovirimat as a treatment against monkeypox?

Combination of interventions more effective at reducing children’s symptoms of depression and anxiety

Novel AI tools accurately predict the role of DNA’s regulatory elements

Study assesses the prevalence of gender-diverse youth in a rural region in Appalachia

Experts use tools from artificial intelligence to rapidly identify substances that cause overdose deaths

Serbia's genome center monitors potential virus mutations to facilitate more effective COVID-19 control

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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