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Researchers synthesize a small molecule that can be used to treat a range of cancers

Researchers at Tel Aviv University and the University of Lisbon have jointly identified and synthesized a small molecule that could be a more accessible and effective alternative to an antibody that is successfully used to treat a range of cancers.

8 Aug 2022

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments.

8 Aug 2022

Powerful injectable gel provides hope for preventing glioblastoma relapse

Like the hardiest weed, glioblastoma almost always springs back -; usually within months after a patient's initial brain tumor is surgically removed.

8 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information to make decisions about patient care.

8 Aug 2022

Yale researchers discover molecular mechanism behind growth of the nervous system

Our nervous system is composed of billions of neurons that speak to each other through their axons and dendrites.

8 Aug 2022

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Researchers from Japan today reported that the first phase II study to evaluate the efficacy and safety of durvalumab and concurrent curative radiation therapy for PD-L1-positive unresectable locally advanced non-small cell lung cancer without chemotherapy met its primary endpoint with tolerable adverse reactions.

8 Aug 2022

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

A large international study of patients with non-small cell lung cancer tumors that are two centimeters or less found that sub lobar surgery was non-inferior to lobectomy, according to results presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

The use of Stereotactic Body Radiotherapy (SBRT) for patients with non-small cell lung cancer can reduce treatment disparities between White and Black patients, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples.

8 Aug 2022

Biological sex differences may be the reason behind higher cancer risk among men than women

Rates of most types of cancer are higher in men than in women for reasons that are unclear. Results from a recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, suggest that the cause may be underlying biological sex differences rather than behavioral differences related to smoking, alcohol use, diet, and other factors.

8 Aug 2022

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.

8 Aug 2022

Every little bit helps: Light walking breaks can reduce the harmful effects of prolonged sitting

A new study reviewed changes in cardiometabolic markers with standing or light walking during a bout of sitting.

8 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

Suicidal ideation may have increased significantly during COVID-19 lockdown

The lockdowns during the COVID-19 pandemic had a significant effect on levels of suicidal ideation, a new study finds.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Tribe embraces recreational marijuana sales on reservation where alcohol is banned

In a growing number of U.S. states, people can both drink alcohol and legally smoke recreational marijuana. In others, they can use alcohol but not pot. But on the Pine Ridge Indian Reservation in South Dakota, the opposite is true: Marijuana is legal, but booze is banned.

8 Aug 2022

Patients and doctors trapped in a gray zone when abortion laws and emergency care mandate conflict

Each week, Dr. Kim Puterbaugh sees several pregnant patients at a Cleveland hospital who are experiencing complications involving bleeding or infection.

8 Aug 2022

Medicine News and Research

Researchers synthesize a small molecule that can be used to treat a range of cancers

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

Powerful injectable gel provides hope for preventing glioblastoma relapse

Overnight EEG studies may help inform care for girls with Rett syndrome

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Disruption of the circadian clocks plays a key role in weight gain

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

Yale researchers discover molecular mechanism behind growth of the nervous system

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Biological sex differences may be the reason behind higher cancer risk among men than women

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Every little bit helps: Light walking breaks can reduce the harmful effects of prolonged sitting

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Suicidal ideation may have increased significantly during COVID-19 lockdown

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Tribe embraces recreational marijuana sales on reservation where alcohol is banned

Patients and doctors trapped in a gray zone when abortion laws and emergency care mandate conflict

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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