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First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Researchers from Japan today reported that the first phase II study to evaluate the efficacy and safety of durvalumab and concurrent curative radiation therapy for PD-L1-positive unresectable locally advanced non-small cell lung cancer without chemotherapy met its primary endpoint with tolerable adverse reactions.

8 Aug 2022

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

A large international study of patients with non-small cell lung cancer tumors that are two centimeters or less found that sub lobar surgery was non-inferior to lobectomy, according to results presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

The use of Stereotactic Body Radiotherapy (SBRT) for patients with non-small cell lung cancer can reduce treatment disparities between White and Black patients, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples.

8 Aug 2022

Biological sex differences may be the reason behind higher cancer risk among men than women

Rates of most types of cancer are higher in men than in women for reasons that are unclear. Results from a recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, suggest that the cause may be underlying biological sex differences rather than behavioral differences related to smoking, alcohol use, diet, and other factors.

8 Aug 2022

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.

8 Aug 2022

Every little bit helps: Light walking breaks can reduce the harmful effects of prolonged sitting

A new study reviewed changes in cardiometabolic markers with standing or light walking during a bout of sitting.

8 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

Suicidal ideation may have increased significantly during COVID-19 lockdown

The lockdowns during the COVID-19 pandemic had a significant effect on levels of suicidal ideation, a new study finds.

8 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Tribe embraces recreational marijuana sales on reservation where alcohol is banned

In a growing number of U.S. states, people can both drink alcohol and legally smoke recreational marijuana. In others, they can use alcohol but not pot. But on the Pine Ridge Indian Reservation in South Dakota, the opposite is true: Marijuana is legal, but booze is banned.

8 Aug 2022

Patients and doctors trapped in a gray zone when abortion laws and emergency care mandate conflict

Each week, Dr. Kim Puterbaugh sees several pregnant patients at a Cleveland hospital who are experiencing complications involving bleeding or infection.

8 Aug 2022

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that the immune system attacks them after implantation, forming a thick layer of scar tissue that blocks insulin release.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Screening individuals for atrial fibrillation (AF) using wearable devices is more cost-effective than screening using conventional methods such as 12-lead electrocardiogram (ECG) and pulse palpation, or than no screening at all, researchers from Massachusetts General Hospital (MGH) have found.

8 Aug 2022

Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says

A clinical trial to test whether three proven smoking cessation treatments could also reduce alcohol intake found no differences between the medications, but the rates of behavior change for alcohol consumption and smoking were high in all treatment groups. Results suggest these medications could play an important role to reduce alcohol use and smoking at the same time. Unexpectedly, nicotine replacement therapy performed as well as the prescription drugs varenicline and cytisine.

8 Aug 2022

New recommendations on how to determine eligibility criteria for lung cancer clinical trials

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

5 Aug 2022

UC San Diego and Rady Children’s Hospital join new study to better understand long-term impact of COVID-19

Researchers at University of California San Diego School of Medicine and Rady Children's Hospital-San Diego have joined a nationwide study to better understand the long-term impact of COVID-19 on patients in the United States across all demographic groups.

5 Aug 2022

Researchers develop new method for visualizing single cell protein secretion with stunning resolution

We have recently witnessed the stunning images of distant galaxies revealed by the James Webb telescope, which were previously visible only as blurry spots.

5 Aug 2022

Five-year, $2.7 million grant could help determine the best treatment for lung cancer patients

The goal: Improve survival rates for lung cancer patients. The question researchers want to answer: Are there new ways to determine the best treatment for these patients?

5 Aug 2022

Medicine News and Research

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Biological sex differences may be the reason behind higher cancer risk among men than women

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Every little bit helps: Light walking breaks can reduce the harmful effects of prolonged sitting

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Suicidal ideation may have increased significantly during COVID-19 lockdown

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Tribe embraces recreational marijuana sales on reservation where alcohol is banned

Patients and doctors trapped in a gray zone when abortion laws and emergency care mandate conflict

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Terminally exhausted T cells may remain competent for transcription, researchers say

Wrist-wearable devices more cost-effective than electrocardiograms and pulse palpation for atrial fibrillation screening

Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says

New recommendations on how to determine eligibility criteria for lung cancer clinical trials

UC San Diego and Rady Children’s Hospital join new study to better understand long-term impact of COVID-19

Researchers develop new method for visualizing single cell protein secretion with stunning resolution

Five-year, $2.7 million grant could help determine the best treatment for lung cancer patients

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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