Lungs News and Research

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NIH stops triple-drug therapy clinical trial for idiopathic pulmonary fibrosis

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns.

22 Oct 2011

NIPPV helps decrease mortality rates among hospitalized COPD patients

Although increased use of noninvasive positive-pressure ventilation (NIPPV) nationwide has helped decrease mortality rates among patients hospitalized with chronic obstructive pulmonary disease (COPD), a small group of patients requiring subsequent treatment with invasive mechanical ventilation (IMV) have a significantly higher risk of death than those placed directly on IMV, according to researchers in the United States who studied patterns of NIPPV use.

22 Oct 2011

Researchers identify cancer cell cycle-regulated mechanism

Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells.

22 Oct 2011

Light to moderate alcohol intake does not appear to increase risk of all-site cancer

A paper from the National Institutes of Health in the United States has evaluated the separate and combined effects of the frequency of alcohol consumption and the average quantity of alcohol drunk per occasion and how that relates to mortality risk from individual cancers as well as all cancers.

21 Oct 2011

Nasal irrigation safe and effective for people with chronic sinus

Before reaching for an over-the-counter medication to relieve cold and allergy symptoms, try a simple source of relief that's been around for centuries.

21 Oct 2011

CMHDRE, DCSNO and CHF team up to help autistic children in New Orleans

The disappearance of reliable healthcare services in New Orleans following Hurricane Katrina left many children with asthma no choice but to seek treatment in emergency rooms across town - if they sought care at all. Xavier University of Louisiana's Center for Minority Health & Health Disparities Research and Education, Daughters of Charity Services of New Orleans and the Children's Health Fund have teamed up to reverse that trend by bringing reliable health care directly to these children.

21 Oct 2011

New metabolic pathway for controlling brain inflammation

A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.

21 Oct 2011

OncoGenex commences enrollment in OGX-427 Phase II trial for bladder cancer

OncoGenex Pharmaceuticals, Inc. announced today that it has initiated patient enrollment in a randomized, Phase II clinical trial evaluating OGX-427, an inhibitor of heat shock protein 27 (Hsp27), in patients with advanced bladder cancer.

21 Oct 2011

Health and fitness tips for office workers

Summer has been over for a few weeks now and vacations have come and gone. With cooler weather approaching, many of us are back into our regular fall month work routines. And for those with sedentary jobs, being back in the office many times means less physical activity and more sitting throughout the day.

20 Oct 2011

'Lance Armstrong effect' could become powerful new cancer weapon

The "Lance Armstrong effect" could become a powerful new weapon to fight cancer cells that develop resistance to chemotherapy, radiation and other treatments, scientists say in a report in the ACS journal Molecular Pharmaceutics.

20 Oct 2011

Winter health and safety tips

Winter is a special time for celebration. It should also be a time for added caution if you or someone in your family is an older adult. It is the season for falls, slips on icy streets, and other dangers that can be especially harmful for older adults. "Something as simple as a fall can be devastating for older men and women," says Dr. Evelyn Granieri, director of the Division of Geriatrics at NewYork-Presbyterian Hospital/The Allen Hospital. "Before the cold weather arrives, it is important to prepare."

20 Oct 2011

RCSI study: Alpha-1 antitrypsin deficiency more prevalent in Ireland

Researchers from the Royal College of Surgeons in Ireland (RCSI), Beaumont Hospital, and Trinity College Dublin have conducted a study which has found that Ireland has one of the highest incidences in the world of a genetic condition that causes severe hereditary emphysema.

20 Oct 2011

BUSM to develop novel technologies for early lung cancer detection

Boston University School of Medicine (BUSM) is the lead institution on a $13.6 million study aimed at developing novel technologies for the early detection of lung cancer.

20 Oct 2011

Link between development of new lymphoid tissue within the lung and protection against TB

New research from the Trudeau Institute may help in the ongoing fight against tuberculosis. Dr. Andrea Cooper's lab has discovered a connection between the development of new lymphoid tissue within the lung and protection against the disease.

19 Oct 2011

New form of respiratory distress syndrome in newborn mice

A discovery by scientists at the Salk Institute for Biological Studies might explain why some premature infants fail to respond to existing treatments for a deadly respiratory distress syndrome (RDS) and offers clues for new ways to treat the breathing disorder.

19 Oct 2011

Study finds why corticosteroids do not work well for COPD patients

Chronic obstructive pulmonary disease (COPD) leads to persistent inflammation of the airways and is typically managed with corticosteroids, a class of anti-inflammatory medication. However, corticosteroids do not improve survival nor alter the progression of COPD and may reduce lung symptoms as little as 20 percent.

19 Oct 2011

Coughing may signal trouble for patients with idiopathic pulmonary fibrosis

A new analysis has found that coughing may signal trouble for patients with the lung-scarring disease known as idiopathic pulmonary fibrosis. The study, published in the journal Respirology, found that patients with the condition who also cough are more likely to develop advanced forms of the disease that may be life threatening.

19 Oct 2011

Calcium with other trace minerals might reduce risk of bowel cancer

Bowel cancer is one of the most common forms of cancer in developed countries but occurs much less frequently in the developing world. A high fat diet, particularly high in saturated fat, can increase a person's risk of developing bowel cancer. In addition to the high content of saturated fat, the 'typical' Western diet contains only low levels of calcium and other minerals.

19 Oct 2011

JPO issues new patent for Genprex's lead lung cancer candidate

A new patent covering tumor suppression technologies, including the company's lead product candidate Oncoprex, was recently awarded to The University of Texas System by the Japan Patent Office. Patent number 4813746 pertains to the discovery that chromosome 3p21.3 genes act as cancer suppressors.

19 Oct 2011

Mass spectrometry reveals precise spatial distribution of drug within tissue

When a new drug is developed, the manufacturer must be able to show that it reaches its intended goal in the body's tissue, and only that goal. Such studies could be made easier with a new method now established at Lund University in Sweden.

18 Oct 2011