Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

European surveillance data shows slight decrease in newly reported hepatitis C cases

European surveillance data show a 10% decrease in newly reported hepatitis C cases between 2016 and 2017. However, with more than 31 000 recorded cases in 2017, diagnoses remain at a high level in the European Union and European Economic Area.

2 Apr 2019

WHO guidelines for chronic hepatitis B fail to detect half of the patients in Ethiopia needing treatment

Current World Health Organization (WHO) guidelines for chronic hepatitis B (CHB) fail to detect half of the patients in need of treatment in Ethiopia, report scientists in the Journal of Hepatology, published by Elsevier.

29 Mar 2019

Sugary drinks may soon face stricter restrictions

Two leading Medical organisations have called for stricter regulations for sugary drinks marketed for children and young adults.

27 Mar 2019

Females on ketogenic diet fail to show metabolic benefits in animal model

The ketogenic diet recently has been touted for weight loss and improving blood sugar control, but a new study finds that females fail to show these metabolic benefits on this high-fat, very low-carbohydrate diet.

25 Mar 2019

Mayo Clinic study identifies potential new drug therapy for liver diseases

Drug therapy may effectively treat a potentially life-threatening condition associated with cirrhosis and other chronic liver diseases, according to a new study by Mayo Clinic researchers.

22 Mar 2019

High-fructose corn syrup fuels growth of colon tumors in mice

Consuming the equivalent of one can of soda per day caused mice predisposed to colon cancer to develop larger tumors, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

22 Mar 2019

Many individuals recovering from addiction continue to suffer from chronic physical disease

Alcohol and other substance-use problems take enormous psychological and societal tolls on millions of Americans.

22 Mar 2019

Current HBV genome sequences help deduce ancient human population movements into Australia

Australian researchers have used current hepatitis B virus (HBV) genome sequences to deduce ancient human population movements into Australia, adding weight to the theory that the mainland Aboriginal population separated from other early humans at least 59 thousand years ago and possibly entered the country near the Tiwi Islands.

19 Mar 2019

CardioMEMS heart failure sensor reliably safe, effectively reduces hospitalizations

In the year following placement of a CardioMEMS heart failure sensor—designed to wirelessly measure and monitor pulmonary artery pressures that can signal worsening heart failure—patients experienced a 58 percent reduction in hospitalization for heart failure, according to research presented at the American College of Cardiology's 68th Annual Scientific Session. Reductions in hospitalizations were seen in both men and women, across all ejection fraction ranges and regardless of race.

18 Mar 2019

Green tea lowers obesity, health risks in mice

Green tea cuts obesity and a number of inflammatory biomarkers linked with poor health in a new study.

14 Mar 2019

Vast majority of children with autism have difficulties that require therapeutic, educational support

Research in the past several years has shown that children can outgrow a diagnosis of autism spectrum disorder, once considered a lifelong condition.

12 Mar 2019

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous interventions, including diet changes and metformin.

8 Mar 2019

Liver tissue model can help investigate the effects of RNA interference

Novel therapies based on a process known as RNA interference hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

6 Mar 2019

Researchers identify first genetic defect linked to biliary atresia

A nationwide consortium of researchers has identified the first genetic defect linked to biliary atresia, a mysterious liver disease that is the leading cause for liver transplantation in children.

5 Mar 2019

Discovery paves the way for simple blood test to detect early stages of NAFLD

One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease - referred to as non-alcoholic fatty liver disease (NAFLD) - causes no symptoms initially but can develop into end-stage liver cirrhosis with limited treatment options.

1 Mar 2019

Lipid-filled particle plays role in immune function and metabolism

Researchers have discovered that fat tissue releases a lipid-filled particle that has a role in immune function and metabolism. The study, in mice, was published online in the journal Science.

1 Mar 2019

Genetic defect linked to pediatric liver disease identified

Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to Biliary atresia, the most common pediatric cause of end-stage liver disease, and the leading indication for liver transplantation in children.

21 Feb 2019

Common acid reflux drugs tied to elevated risk for kidney disease

Proton pump inhibitors, which include well-known brand names Prilosec, Nexium and Prevacid, are among the most commonly prescribed medications in the world. Approximately 10 percent of adults in the United States take these drugs for frequent heartburn, acid reflux and gastroesophageal reflux disease.

19 Feb 2019

Low physical fitness during adolescence associated with later receipt of disability pension

Obesity or low physical fitness during adolescence is strongly associated with disability pension later in life. This is shown in a study of more than one million Swedish men, published in Annals of Internal Medicine by researchers at Karolinska Institutet.

12 Feb 2019

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

During a study spanning nearly a decade, researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center have linked the protein clusterin - for the first time -- to many different facets of cardiometabolic syndrome risk through its actions in the liver.

4 Feb 2019

Liver Disease News and Research

Further Reading

European surveillance data shows slight decrease in newly reported hepatitis C cases

WHO guidelines for chronic hepatitis B fail to detect half of the patients in Ethiopia needing treatment

Sugary drinks may soon face stricter restrictions

Females on ketogenic diet fail to show metabolic benefits in animal model

Mayo Clinic study identifies potential new drug therapy for liver diseases

High-fructose corn syrup fuels growth of colon tumors in mice

Many individuals recovering from addiction continue to suffer from chronic physical disease

Current HBV genome sequences help deduce ancient human population movements into Australia

CardioMEMS heart failure sensor reliably safe, effectively reduces hospitalizations

Green tea lowers obesity, health risks in mice

Vast majority of children with autism have difficulties that require therapeutic, educational support

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

Liver tissue model can help investigate the effects of RNA interference

Researchers identify first genetic defect linked to biliary atresia

Discovery paves the way for simple blood test to detect early stages of NAFLD

Lipid-filled particle plays role in immune function and metabolism

Genetic defect linked to pediatric liver disease identified

Common acid reflux drugs tied to elevated risk for kidney disease

Low physical fitness during adolescence associated with later receipt of disability pension

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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