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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study reveals why colorectal cancer still returns in some patients after treatment

Cetuximab, marketed as Erbitux, is one of the key therapies for metastatic colorectal cancer. Yet the cancer still returns in some patients, shortening overall survival.

17 Nov 2015

MIPT researchers patent graphene biosensors that may accelerate development of novel drugs

The US Patent Office has recently published the patent application (no. US 2015/0301039), which was filed by the MIPT in May this year and is titled Biological Sensor and a Method of the Production of Biological Sensor. In Russia, this development is already protected by the patent No. 2527699 with a priority date of February 20, 2013. The key feature of the sensor is the use of a linking layer for biomolecule immobilization comprising a thin film of graphene or graphene oxide.

17 Nov 2015

MedUni Vienna researchers discover genetic cause of a rare disease

Researchers at MedUni Vienna have discovered the genetic cause of a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when they reach school age.

15 Nov 2015

Natera's total revenues decrease 2.9% to $44.9 million in third quarter 2015

Natera, Inc., a leader in non-invasive genetic testing and the analysis of circulating cell-free DNA, today reported financial results for the third quarter ended September 30, 2015 and provided an update on recent business progress.

From Natera 13 Nov 2015

Entirely new enzymatic process of DNA synthesis

Cleaver Scientific has supplied a UV Sterilization Cabinet to Touchlight Genetics (Hampton, UK) who had sought a sterile workspace for the preparation of their RNA and DNA samples and templates.

From Cleaver Scientific Ltd 12 Nov 2015

Baylor Miraca Genetics Laboratories licenses SNP probe technology from OGT

Oxford Gene Technology (OGT), The Molecular Genetics Company, has entered into a deal with Baylor Miraca Genetics Laboratories (BMGL), licensing the use of OGT’s proprietary single nucleotide polymorphism (SNP) array probe technology.

From Oxford Gene Technology 12 Nov 2015

Researchers reveal how charged gold nanoparticles influence structure of DNA and RNA

Researchers at North Carolina State University have used computational modelling to shed light on precisely how charged gold nanoparticles influence the structure of DNA and RNA - which may lead to new techniques for manipulating these genetic materials.

12 Nov 2015

Ovarian cancer patients with a history of oral contraceptive use have better outcomes

Patients who develop ovarian cancer appear to have better outcomes if they have a history of oral contraceptive use, according to a study by Mayo Clinic researchers published in the current issue of the journal BMC Cancer.

12 Nov 2015

Discovery could offer clues to how some viruses control expression of genetic material

Researchers at Case Western Reserve University and the University of Michigan have produced the first image of an important human protein as it binds with ribonucleic acid (RNA), a discovery that could offer clues to how some viruses, including HIV, control expression of their genetic material.

12 Nov 2015

New research examines previously unknown secret to DNA repair

Michael Hendzel knows all too well that there is little that people can do to control the stability of their genetic code. But he hopes his latest research will help impact this elusive and crucial aspect of medicine. Published in Nature Cell Biology, this research explores a previously unknown secret to DNA repair.

12 Nov 2015

Crucial change in single DNA base predisposes children to aggressive form of cancer

Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form.

12 Nov 2015

Study shows rare HER2 missense mutations do not spread breast cancer on their own

Results of a new laboratory study by Johns Hopkins Kimmel Cancer Center researchers suggests that some rare “missense” mutations in the HER2 gene are apparently not — on their own — capable of causing breast cancer growth or spread.

12 Nov 2015

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease.

11 Nov 2015

Biocept receives European patent covering antibody usage in capture of rare cells

Biocept, Inc., a molecular diagnostics company commercializing and developing liquid biopsies to improve the diagnosis and treatment of cancer, announces that the European Patent Office has awarded the patent, "DEVICES AND METHODS OF CELL CAPTURE AND ANALYSIS," as announced in the European Bulletin dated November 11, 2015.

11 Nov 2015

Phase I clinical trial shows investigational anticancer therapeutic is safe, tolerable in lymphoma patients

Results from a phase I clinical trial showed that the first-in-class, investigational, anticancer therapeutic pevonedistat was safe, tolerable, and had some anticancer activity in heavily pretreated patients with relapsed/refractory lymphoma.

11 Nov 2015

Research may offer new treatments for patients suffering from severe diarrhea

Everyone has suffered from it. It's ranged from mild to severe. It's a condition that's most-often described in a whisper.

11 Nov 2015

Deep, uniform exome coverage in one day

Integrated DNA Technologies (IDT), introduces its new xGen® Exome Research Panel v1.0 for insightful analysis of the human exome via next generation sequencing.

From Integrated DNA Technologies 10 Nov 2015

Researchers find greater genetic diversity among cancer cells than anticipated

The most rigorous genetic sequencing ever carried out on a single tumor reveals far greater genetic diversity among cancer cells than anticipated. Researchers from the University of Chicago and the Beijing Institute of Genomics estimate that the tumor, about 3.5 centimeters in diameter, contained more than 100 million distinct mutations within the coding regions of its genes—thousands of times more than expected.

10 Nov 2015

New method may extend use of noninvasive prenatal testing to detect chromosomal abnormalities

Researchers at the University of California, San Diego School of Medicine developed a method to expand the types of chromosomal abnormalities that noninvasive prenatal testing (NIPT) can detect. The study, published November 9 by Proceedings of the National Academy of Sciences, uses a semiconductor sequencing platform to identify small chromosomal deletions or duplications, such as occur in Cri du Chat Syndrome and DiGeorge Syndrome, with a simple blood test from the expectant mother.

10 Nov 2015

Drug compounds target multiple pathways associated with myotonic dystrophy type 1

Efforts to treat myotonic dystrophy type 1, the most common form of muscular dystrophy, are in their infancy. In a new study, researchers report they have added new capabilities to an experimental drug agent that previously defeated only one of DM1's many modes of action. Their retooled compounds interrupt the disease's pathology in three ways.

10 Nov 2015

DNA News and Research

Further Reading

Study reveals why colorectal cancer still returns in some patients after treatment

MIPT researchers patent graphene biosensors that may accelerate development of novel drugs

MedUni Vienna researchers discover genetic cause of a rare disease

Natera's total revenues decrease 2.9% to $44.9 million in third quarter 2015

Entirely new enzymatic process of DNA synthesis

Baylor Miraca Genetics Laboratories licenses SNP probe technology from OGT

Researchers reveal how charged gold nanoparticles influence structure of DNA and RNA

Ovarian cancer patients with a history of oral contraceptive use have better outcomes

Discovery could offer clues to how some viruses control expression of genetic material

New research examines previously unknown secret to DNA repair

Crucial change in single DNA base predisposes children to aggressive form of cancer

Study shows rare HER2 missense mutations do not spread breast cancer on their own

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Biocept receives European patent covering antibody usage in capture of rare cells

Phase I clinical trial shows investigational anticancer therapeutic is safe, tolerable in lymphoma patients

Research may offer new treatments for patients suffering from severe diarrhea

Deep, uniform exome coverage in one day

Researchers find greater genetic diversity among cancer cells than anticipated

New method may extend use of noninvasive prenatal testing to detect chromosomal abnormalities

Drug compounds target multiple pathways associated with myotonic dystrophy type 1

eBook: A guide to RNA sequencing eBook

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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