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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Potential new drug target for acute myeloid leukemia

New treatment options are badly needed for acute myeloid leukemia, a relatively rare form of cancer. The malignancy begins in the bone marrow, and from there can spread rapidly to the bloodstream, depriving the body of the essential blood cells that carry oxygen and fight infections.

23 Oct 2015

Drug engineered from bananas could fight off wide range of viruses

A banana a day may not keep the doctor away, but a substance originally found in bananas and carefully edited by scientists could someday fight off a wide range of viruses, new research suggests.

23 Oct 2015

Successful treatment of rare neurodegenerative disease exemplifies potential of precision medicine

A 20-month-old girl suffering from a rare neurodegenerative disease was diagnosed by exome sequencing and successfully treated.

23 Oct 2015

Juneau Biosciences presents new genetic discoveries in endometriosis at annual ASRM meeting

This week, Juneau Biosciences, LLC presented new discoveries concerning the genetics of endometriosis at the annual American Society of Reproductive Medicine (ASRM) meeting in Baltimore, MD.

23 Oct 2015

DNA study reveals basic principle of gene regulation

A study of where and how an enzyme cuts DNA may have inadvertently revealed a basic principle of gene regulation, say researchers in Boston Children's Hospital's Program in Cellular and Molecular Medicine (PCMM).

23 Oct 2015

New test may help predict spread of breast cancer to the brain

Women with particularly aggressive forms of breast cancer could be identified by a test that predicts whether the disease is likely to spread to the brain.

22 Oct 2015

Ground-breaking discovery helps scientists view DNA damage with crystal clarity

Scientists have developed a new technique for looking at the initial steps of DNA oxidation – a process which can lead to DNA damage, mutations and cancers. The breakthrough, which uses DNA in crystals, should help related research in the fields of cancer medicine and drug development.

22 Oct 2015

RUCDR Infinite Biologics awarded $6 million grant from NINDS

The National Institute of Neurological Disorders and Stroke has awarded a five-year grant worth up to $6,034,323 to RUCDR Infinite Biologics, a unit of Rutgers' Human Genetics Institute of New Jersey. RUCDR, which is located on Rutgers' Busch Campus in Piscataway, is the world's largest university-based biorepository.

20 Oct 2015

Bioengineers develop continuously tunable method to find and quantify DNA, RNA biomarkers

A Rice University laboratory has developed a continuously tunable method to find and quantify DNA and RNA biomarkers.

20 Oct 2015

Scientists reveal link between depression and paraventricular thalamus

Scientists from the RIKEN Brain Science Institute have shown that a mouse strain with a mutation that leads to dysfunction of mitochondria--the "powerhouses" that provide energy to cells--spontaneously undergo periodic episodes of depression-like behavior that resemble those in human. Through this research, published in Molecular Psychiatry, the scientists uncovered a link between depression and the paraventricular thalamus, a region of the brain not previously tied to depression.

20 Oct 2015

New research seeks to improve understanding of how breast cancer starts

Dr Michalak was awarded a highly competitive, four-year career development fellowship from the National Breast Cancer Foundation for her research into breast stem cells. The funding is helping to further her research, which seeks to improve our understanding of how breast cancer starts.

20 Oct 2015

New genetic discovery could lead to better treatment for X-linked diseases

Think back to middle school biology class, when you learned that boys have an X and a Y chromosome inside each cell, and girls have two X's.

20 Oct 2015

DelMar reports positive data from preclinical study of VAL-083 for treatment of ovarian cancer

DelMar Pharmaceuticals, Inc., a biopharmaceutical company focused on the development and commercialization of new cancer therapies, announced that yesterday it presented positive preclinical data demonstrating the promising potential of its lead product candidate VAL-083 (dianhydrogalactitol) as a treatment for ovarian cancer.

19 Oct 2015

Sequenom enters into clinical collaboration with CU School of Medicine

Sequenom, Inc., a life sciences company committed to enabling healthier lives through the development of innovative products and services, today announced that it has entered into a clinical collaboration with the University of Colorado Denver, School of Medicine.

19 Oct 2015

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

HALO study to assess how recreational running puts people at risk of developing OA of the knee in later life

Every day, millions of us pull on our trainers and hit the streets in an attempt to get fitter while enjoying the great outdoors. But is our love affair with running storing up health problems for us in the future? That's the question a new international study led by researchers at The University of Nottingham, as part of the Arthritis Research UK Centre for Sport, Exercise and Osteoarthritis, is aiming to answer - with a little help from several thousand participants in the increasingly popular weekly parkrun events.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

New UCL study highlights genes associated with schizophrenia and obesity

Genes involved in schizophrenia and obesity have been highlighted in a new UCL study, which could lead to a better understanding of the DNA variants which affect risk of these conditions and aid the development of improved strategies for prevention and treatment.

18 Oct 2015

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

A research conducted by Juan Méndez, Head of the DNA Replication Group of the Spanish National Cancer Research Centre (CNIO), sheds light on the molecular mechanisms of ageing of the stem cells responsible for regenerating blood cells and opens up a new avenue for reducing their progressive functional decline with age.

16 Oct 2015

NEB releases new NEBNext Ultra II DNA Library Prep Kit

New England Biolabs today announced the release of the NEBNext Ultra II DNA Library Prep Kit for Illumina next generation sequencing systems. The new Ultra II kit substantially improves upon its predecessor to produce libraries of both higher quality and higher yield from a variety of sample types, including challenging ones, such as formalin-fixed, paraffin-embedded (FFPE) samples and those containing low amounts of input DNA.

From New England Biolabs 16 Oct 2015

DNA News and Research

Further Reading

Potential new drug target for acute myeloid leukemia

Drug engineered from bananas could fight off wide range of viruses

Successful treatment of rare neurodegenerative disease exemplifies potential of precision medicine

Juneau Biosciences presents new genetic discoveries in endometriosis at annual ASRM meeting

DNA study reveals basic principle of gene regulation

New test may help predict spread of breast cancer to the brain

Ground-breaking discovery helps scientists view DNA damage with crystal clarity

RUCDR Infinite Biologics awarded $6 million grant from NINDS

Bioengineers develop continuously tunable method to find and quantify DNA, RNA biomarkers

Scientists reveal link between depression and paraventricular thalamus

New research seeks to improve understanding of how breast cancer starts

New genetic discovery could lead to better treatment for X-linked diseases

DelMar reports positive data from preclinical study of VAL-083 for treatment of ovarian cancer

Sequenom enters into clinical collaboration with CU School of Medicine

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

HALO study to assess how recreational running puts people at risk of developing OA of the knee in later life

BET protein family plays key role in regulation of normal neuronal development and function

New UCL study highlights genes associated with schizophrenia and obesity

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

NEB releases new NEBNext Ultra II DNA Library Prep Kit

eBook: A guide to RNA sequencing eBook

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