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Conscience's open science competition yields hits for new Parkinson's drugs

As part of its pioneering approach to drug discovery, the Canadian nonprofit Conscience announced today that its first open science competition has resulted in the identification of seven promising molecules, or "hits," that show potential for new, more effective drugs for familial Parkinson's disease.

16 Jan 2024

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Breast cancer is the most common cancer in women. The development of breast cancer often originates from epithelial cells in the mammary gland – the very cells that specialise in milk production during and after pregnancy.

16 Jan 2024

Amnesia caused by head injury could potentially be reversed, mouse study suggests

A mouse study designed to shed light on memory loss in people who experience repeated head impacts, such as athletes, suggests the condition could potentially be reversed.

16 Jan 2024

Breakthrough nano-shield blocks selective allergic reactions

Northwestern University researchers have developed the first selective therapy to prevent allergic reactions, which can range in severity from itchy hives and watery eyes to trouble breathing and even death.

16 Jan 2024

Research uncovers cells-of-origin for breast cancer in BRCA2 mutation carriers

Australian scientists have pinpointed likely 'cells-of-origin', the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.

16 Jan 2024

Binghamton University develops app to help study and prevent falls in older adults

Researchers at Binghamton University, State University of New York's Motion Analysis Research Laboratory have developed an app to help study and prevent falls in older adults.

16 Jan 2024

Revolutionary transparent graphene microelectrodes enhance brain imaging and stimulation

The decoding of single-cell and average neural activities from surface potentials.

15 Jan 2024

mRNA COVID-19 vaccines highly effective in preventing hospitalizations among adolescents in Nordic study

Study evaluated the effectiveness of mRNA COVID-19 vaccines (BNT162b2, mRNA-1273, and heterologous schedules) in preventing hospitalization among adolescents in Nordic countries, finding high protection rates of 73% to 86% at six months.

14 Jan 2024

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes, with new technique enhancing chromosome analysis

13 Jan 2024

Swedish blood donor study reveals high prevalence of undiagnosed TBE infections

The number of infections by the tick-borne TBE virus that are not detected by health services is far higher than previously assumed.

12 Jan 2024

FDA-approved drug may help to decrease pain after surgery, study finds

Researchers in the Department of Anesthesia and Perioperative Medicine at the Medical University of South Carolina (MUSC) have found that an FDA-approved drug may help to decrease pain after surgery.

12 Jan 2024

Stromal cells may be useful in assessing prostate tumors' potential to spread

Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be useful in assessing these tumors' potential to spread, and may even be targets for future prostate cancer treatments, according to a study led by researchers at Weill Cornell Medicine.

12 Jan 2024

Gum bacteria fuel COPD through immune cell activation

Severe gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how the connection plays out in the immune system remains unclear.

12 Jan 2024

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

Researchers introduced a non-invasive, sensitive method for monitoring gene expression in the brain using engineered reporters called released markers of activity, which can exit the brain into the blood for easy detection.

12 Jan 2024

First organoid model of the human conjunctiva produced

The Organoid group at the Hubrecht Institute produced the first organoid model of the human conjunctiva. These

11 Jan 2024

Revolutionary blood test monitors gene expression dynamics in the brain

The brain is the most protected organ in the body, sheathed in a complex and nearly impenetrable barrier of specialized blood vessels.

11 Jan 2024

Streamlined Laboratory Integration With INTEGRA’s Electronic and Automated Liquid Handling Solutions

Rapid technological advancements in the life sciences field have made automation a key focus for many laboratories, and INTEGRA Biosciences is proud to provide advanced liquid handling solutions to streamline laboratory protocols.

From INTEGRA Biosciences 11 Jan 2024

"Alkaline water" fails to be an effective alternative for prevention of recurrent urinary stones

Bottled water marketed as "alkaline water" is unlikely to be an effective alternative for prevention of recurrent urinary stones, reports a study in the January issue of The Journal of Urology, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

10 Jan 2024

Silicone wristbands track personal PAH exposure

Environmental epidemiologists at Columbia University Mailman School of Public Health, in collaboration with an interdisciplinary team of researchers at Oregon State University, Pacific Northwest National Labs, and Mt. Sinai School of Medicine, report on the findings of a new study of air pollution exposures collected using personal wristband monitors worn by pregnant individuals in New York City matched with data from a questionnaire.

10 Jan 2024

Study: Low-dose calcium equally effective as high-dose in preventing preeclampsia

To help prevent preeclampsia and preterm birth-;common complications in pregnancy that can be fatal to women and newborns-;low-dose calcium supplementation (equivalent to one 500-milligram pill per day) may be as effective as the World Health Organization (WHO)'s recommended high-dose calcium supplementation (equivalent to three 500-milligram pills taken throughout each day), according to a new study led by Harvard T.H. Chan School of Public Health and collaborators in India and Tanzania.

10 Jan 2024

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Laboratory News and Research

Conscience's open science competition yields hits for new Parkinson's drugs

Jena researchers unravel PAPAS RNA's impact on breast cancer growth and metastasis

Amnesia caused by head injury could potentially be reversed, mouse study suggests

Breakthrough nano-shield blocks selective allergic reactions

Research uncovers cells-of-origin for breast cancer in BRCA2 mutation carriers

Binghamton University develops app to help study and prevent falls in older adults

Revolutionary transparent graphene microelectrodes enhance brain imaging and stimulation

mRNA COVID-19 vaccines highly effective in preventing hospitalizations among adolescents in Nordic study

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes

Swedish blood donor study reveals high prevalence of undiagnosed TBE infections

FDA-approved drug may help to decrease pain after surgery, study finds

Stromal cells may be useful in assessing prostate tumors' potential to spread

Gum bacteria fuel COPD through immune cell activation

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

First organoid model of the human conjunctiva produced

Revolutionary blood test monitors gene expression dynamics in the brain

Streamlined Laboratory Integration With INTEGRA’s Electronic and Automated Liquid Handling Solutions

"Alkaline water" fails to be an effective alternative for prevention of recurrent urinary stones

Silicone wristbands track personal PAH exposure

Study: Low-dose calcium equally effective as high-dose in preventing preeclampsia

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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