DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New partnership aims to provide high-tech healthcare learning opportunities for pediatric patients

A new partnership between The University of Texas at Arlington Libraries and Cook Children's Medical Center in Fort Worth will mean new high-tech healthcare learning opportunities for pediatric patients.

5 Aug 2015

University of Liverpool study finds that HIV can continue to grow in patients despite treatment

HIV can continue to grow in patients who are thought to be responding well to treatment, according to research by the University of Liverpool.

5 Aug 2015

Baseline HBsAg, platelet count predict spontaneous HBsAg seroclearance

Hepatitis B surface antigen level and platelet count at baseline are significantly associated with spontaneous HBsAg seroclearance in hepatitis B virus carriers and those with chronic infection, research suggests.

4 Aug 2015

Research: Critical aspects of human genome's regulatory program encoded by genomic sequence elements

Since the classical studies of Jacob and Monod in the early 1960s, it has been evident that genome sequences contain not only blueprints for genes and the proteins that they encode, but also the instructions for a coordinated regulatory program that governs when, where and to what extent these genes and proteins are expressed.

4 Aug 2015

SGI-DNA recognized by Frost & Sullivan for BioXp 3200 System

SGI-DNA, a Synthetic Genomics, Inc. company, was recently recognized by Frost & Sullivan for its groundbreaking innovation in genomic technologies for the BioXp 3200 System, an instrument with the capacity to simultaneously build 32 unique, double-stranded DNA fragments to study gene function, pathways, and whole genomes.

4 Aug 2015

European Commission grants orphan drug designation to SGX301 for treatment of CTCL

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today that the European Commission, acting on the positive recommendation from the European Medicines Agency Committee for Orphan Medicinal Products (COMP), has granted orphan drug designation to synthetic hypericin (the active pharmaceutical ingredient in SGX301) for the treatment of cutaneous T-cell lymphoma (CTCL), a rare disease and a class of non-Hodgkin's lymphoma, a type of cancer of the white blood cells that are an integral part of the immune system.

4 Aug 2015

California Initiative to Advance Precision Medicine selects two demonstration projects

Two demonstration projects that aim to yield quick results for patients have been selected by the new California Initiative to Advance Precision Medicine, a public-private effort launched by Governor Edmund G. Brown Jr.

4 Aug 2015

Northwestern gets $17.5 million NIH grant to invent, develop implantable drug delivery system for HIV prevention

Northwestern Medicine scientists have received a five-year, $17.5 million grant from the National Institutes of Health for an interdisciplinary project that aims to invent, develop and test an implantable drug delivery system to protect high-risk individuals from HIV infection for up to a year at a time.

4 Aug 2015

Penn Medicine devises new approach to develop vaccines against lethal diseases

Researchers at the Perelman School of Medicine at the University of Pennsylvania have devised an entirely new approach to vaccines - creating immunity without vaccination.

4 Aug 2015

Stress responder plays critical, early step in repairing DNA damage

DNA damage increases the risk of cancer, and researchers have found that a protein, known to rally when cells get stressed, plays a critical, early step in its repair.

4 Aug 2015

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

DNA double-strand breaks (DSBs) are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy. New information published this week reveals more about why this occurs and how these breaks can be repaired.

4 Aug 2015

First biodegradable gene delivery system efficiently penetrates human airway mucus barrier of lung tissue

Researchers at the Johns Hopkins University School of Medicine, Johns Hopkins University Department of Chemical and Biomolecular Engineering, and Federal University of Rio de Janeiro in Brazil have designed a DNA-loaded nanoparticle that can pass through the mucus barrier covering conducting airways of lung tissue — proving the concept, they say, that therapeutic genes may one day be delivered directly to the lungs to the levels sufficient to treat cystic fibrosis (CF), chronic obstructive pulmonary disease, asthma and other life-threatening lung diseases.

4 Aug 2015

Scientists successfully test new tumor diagnosis method

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf, in cooperation with colleagues at the University of Zurich and the Ruhr-Universität Bochum, have for the first time successfully tested a new tumor diagnosis method under near-real conditions. The new method first sends out an antibody as a "spy" to detect the diseased cells and then binds to them.

4 Aug 2015

Combining chemotherapy and birinapant effective against high-grade serous ovarian cancer

High-grade serous ovarian cancer often responds well to the chemotherapy drug carboplatin, but why it so frequently comes back after treatment has been a medical mystery.

4 Aug 2015

RNA-binding protein ROQUIN regulates response to DNA damage

Messenger (mRNA) molecules are a key component of protein biosynthesis. They are first transcribed as a "working copy" of the DNA and then translated into protein molecules.

3 Aug 2015

Researchers uncover strong evidence for genetic causes of cerebral palsy

Cerebral palsy (CP) is the most common cause of physical disability in children. It has historically been considered to be caused by factors such as birth asphyxia, stroke and infections in the developing brain of babies.

3 Aug 2015

Animal study shows children exposed to famine grow smaller, become susceptible to metabolic diseases

Starvation early in life can alter an organism for generations to come, according to a new study in roundworms. The effects are what Duke University biologist Ryan Baugh terms a "bet-hedging strategy."

3 Aug 2015

Environmental factors promote genetic mutations, have underappreciated effect on disease, evolution

Washington State University researchers say environmental factors are having an underappreciated effect on the course of disease and evolution by prompting genetic mutations through epigenetics, a process by which genes are turned on and off independent of an organism's DNA sequence.

3 Aug 2015

BRCA gene mutations and ovarian cancer: an interview with Dr Matulonis, Harvard Medical School

The BRCA gene encodes for the BRCA proteins, BRCA1 and BRCA2. These proteins are very important in repairing DNA, which they do by correcting double-stranded breaks.

2 Aug 2015

FDA accepts Mundipharma EDO's Investigational New Drug Application for EDO-S101

Mundipharma EDO GmbH (Early Development in Oncology) is pleased to announce that the United States Food and Drug Administration has accepted the company's Investigational New Drug Application ("IND") for EDO-S101, a fusion molecule to treat relapsed/refractory haematologic malignancies and solid tumours.

31 Jul 2015

DNA News and Research

Further Reading

New partnership aims to provide high-tech healthcare learning opportunities for pediatric patients

University of Liverpool study finds that HIV can continue to grow in patients despite treatment

Baseline HBsAg, platelet count predict spontaneous HBsAg seroclearance

Research: Critical aspects of human genome's regulatory program encoded by genomic sequence elements

SGI-DNA recognized by Frost & Sullivan for BioXp 3200 System

European Commission grants orphan drug designation to SGX301 for treatment of CTCL

California Initiative to Advance Precision Medicine selects two demonstration projects

Northwestern gets $17.5 million NIH grant to invent, develop implantable drug delivery system for HIV prevention

Penn Medicine devises new approach to develop vaccines against lethal diseases

Stress responder plays critical, early step in repairing DNA damage

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

First biodegradable gene delivery system efficiently penetrates human airway mucus barrier of lung tissue

Scientists successfully test new tumor diagnosis method

Combining chemotherapy and birinapant effective against high-grade serous ovarian cancer

RNA-binding protein ROQUIN regulates response to DNA damage

Researchers uncover strong evidence for genetic causes of cerebral palsy

Animal study shows children exposed to famine grow smaller, become susceptible to metabolic diseases

Environmental factors promote genetic mutations, have underappreciated effect on disease, evolution

BRCA gene mutations and ovarian cancer: an interview with Dr Matulonis, Harvard Medical School

FDA accepts Mundipharma EDO's Investigational New Drug Application for EDO-S101

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest Life Science News