Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Study finds new strains of hepatitis C virus in sub-Saharan Africa

The largest population study of hepatitis C in Africa has found three new strains of the virus circulating in the general population in sub-Saharan Africa.

17 Dec 2018

SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns

Saint Louis University researchers are studying how fetal exposure to inflammation can alter immune responses after birth.

12 Dec 2018

Lower BMI before obesity surgery predicts greater post-operative weight loss, study finds

Lower BMI before bariatric surgery predicts greater post-operative weight loss, a new study from the University of Eastern Finland finds.

11 Dec 2018

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

Today, the Chan Zuckerberg Initiative announced funding for open-source software efforts to improve image analysis and visualization in biomedicine. Microscopy -- critical to modern cell biology -- generates large volumes of complex data that pose significant challenges for analysis and visualization.

7 Dec 2018

Elevated hormone flags liver disease in mice with serious genomic disorder

Researchers have discovered that a hormone, fibroblast growth factor 21 (FGF21), is extremely elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia (MMA), a serious genomic disorder.

6 Dec 2018

Study examines whether taking multiple medications for heart failure can limit abilities in older adults

As we age, we tend to develop a number of chronic health conditions and concerns. Often, managing health problems can mean that older adults may take many different medications. When older adults take five or more medicines (a scenario health experts call "polypharmacy", it can increase the risk of harmful side effects.

3 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Higher rates of alcohol use found among Hispanic Americans who are more 'Americanized'

Higher rates of alcohol use and drinking consequences are found among Hispanic American adolescents and adults who are more "Americanized," according to a new study authored by Southern Methodist University professor Priscilla Lui and her colleague, Byron Zamboanga, at Smith College.

27 Nov 2018

Using Pre-Clinical Imaging to Detect Cancer

In this interview, Émilie Beaulieu Ouellet, Application Scientist for life science imaging at Photon Etc talks to New-Medical about their range of preclinical infrared imagers and how they can allow cancer detection.

From Photon etc. 27 Nov 2018

People from cold regions tend to drink more finds study

A new study has shown that people who live in cold and dark regions tend to be heavy drinkers. The data comes from participants of around 193 countries and shows that there is a connection between weather, alcohol consumption as well as alcohol associated liver disease.

20 Nov 2018

Routine HCV testing in correctional facilities can best identify and treat disease, say researchers

Results from a new study led by Boston Medical Center (BMC) found routine Hepatitis C testing identified a significant number of cases that would have been missed by targeted testing among a population of individuals in Washington State prisons.

20 Nov 2018

Infant gut microbes altered by mother's obesity may increase risk for future disease

Infant gut microbes altered by their mother's obesity can cause inflammation and other major changes within the baby, increasing the risk of obesity and non-alcoholic fatty liver disease later in life, according to researchers at the University of Colorado Anschutz Medical Campus.

16 Nov 2018

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

University of Minnesota Medical School researchers have made a discovery which could lead to a new way of thinking about how disease pathogenesis in the liver is regulated, which is important for understanding the condition nonalcoholic fatty liver disease, which is incredibly common and growing.

16 Nov 2018

Study identifies factors tied to greater risk of advanced liver disease in cystic fibrosis patients

Children's Hospital Colorado pediatric gastroenterologist, Michael Narkewicz, MD, recently shared results of the Prospective Study of Ultrasound to Predict Hepatic Cirrhosis in Cystic Fibrosis, which sought to determine if liver ultrasounds could identify children and adolescents with cystic fibrosis who are at greater risk of developing advanced liver disease.

13 Nov 2018

Researchers identify epigenetic changes that increase risk of type 2 diabetes

Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes increase the risk of type 2 diabetes.

8 Nov 2018

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease, the accumulation of fat in the liver of people who drink little or no alcohol, affects 1 in 3 Americans. NAFLD is a significant risk factor for Type 2 diabetes, insulin resistance, and hepatic carcinoma, and incidence of the disease is increasing with the growing obesity epidemic in the United States.

8 Nov 2018

Circadian clock could play key role in the fight against liver cancer

The body's internal clock could play a critical role in the fight against certain types of liver cancer, according to a preclinical study by scientists from The University of Texas Health Science Center at Houston (UTHealth). The results were published recently in the journal Nature Communications.

8 Nov 2018

Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure

Currently, the only therapy for metabolic liver disease is an organ transplant. Tracy Grikscheit, MD, an attending physician and regenerative medicine scientist at Children's Hospital Los Angeles, hopes to change that reality.

7 Nov 2018

Study identifies novel missense mutation affecting YARS causes multisystem disease

Researchers have identified a novel missense mutation in tyrosyl-tRNA synthetase (YARS c.499C>A, p.Pro167Thr) that causes a severe recessive disorder in affected individuals.

7 Nov 2018

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Genentech, a member of the Roche Group , announced today that the randomized Phase III CLL14 study, which evaluated fixed-duration Venclexta® in combination with Gazyva® in people with previously untreated chronic lymphocytic leukemia and co-existing medical conditions, met its primary endpoint and showed a statistically significant reduction in the risk of disease worsening or death compared to standard-of-care Gazyva plus chlorambucil.

1 Nov 2018

Liver Disease News and Research

Further Reading

Study finds new strains of hepatitis C virus in sub-Saharan Africa

SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns

Lower BMI before obesity surgery predicts greater post-operative weight loss, study finds

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

Elevated hormone flags liver disease in mice with serious genomic disorder

Study examines whether taking multiple medications for heart failure can limit abilities in older adults

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Higher rates of alcohol use found among Hispanic Americans who are more 'Americanized'

Using Pre-Clinical Imaging to Detect Cancer

People from cold regions tend to drink more finds study

Routine HCV testing in correctional facilities can best identify and treat disease, say researchers

Infant gut microbes altered by mother's obesity may increase risk for future disease

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

Study identifies factors tied to greater risk of advanced liver disease in cystic fibrosis patients

Researchers identify epigenetic changes that increase risk of type 2 diabetes

GW study examines impact of nervous system on non-alcoholic fatty liver disease

Circadian clock could play key role in the fight against liver cancer

Regenerative medicine scientist receives $1.3 million to study stem cell therapy for liver failure

Study identifies novel missense mutation affecting YARS causes multisystem disease

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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