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Study uncovers how tumors backfire on neoadjuvant chemotherapy

Some patients with breast cancer receive chemotherapy before the tumor is removed with surgery. This approach, called 'neoadjuvant' therapy, helps to reduce the size of the tumor to facilitate breast-conserving surgery, and can even eradicate the tumor, leaving few or no cancerous cells for the surgeon to remove.

2 Jan 2019

China’s war on air pollution is leading to rise of ozone pollution

In early 2013, the Chinese government declared a war on air pollution and began instituting stringent policies to regulate the emissions of fine particulate matter, a pollutant known as PM 2.5. Cities restricted the number of cars on the road, coal-fired power plants reduced emissions or were shuttered and replaced with natural gas.

1 Jan 2019

Peptide isolated from spirulina extract may counteract arterial hypertension

Spirulina is more and more celebrated as a "superfood" because of its possible beneficial properties, albeit its mechanism of action is still subjected to investigation. With the scientific name of Arthrospira platensis, spirulina is a cyanobacterium, a bacterium capable of photosynthesis. Sometimes classified as a "blue algae", it was supposedly used as a food by the Aztecs.

31 Dec 2018

Sound can affect perception of touch in mice

Our eyes, ears and skin are responsible for different senses. Moreover, our brain assigns these senses to different regions: the visual cortex, auditory cortex and somatosensory cortex. However, it is clear that there are anatomical connections between these different cortices such that brain activation to one sense can influence brain activation to another

30 Dec 2018

Genetically diverse mouse models improves usability for precision medicine for Alzheimer's

Incorporating genetic diversity into a mouse model of Alzheimer's disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging, part of the National Institutes of Health.

28 Dec 2018

Speedier examinations may be useful in public health assessments of scabies

For years, the diagnosis of scabies has relied on time-consuming and intrusive full-body examinations. Now, researchers reporting in PLOS Neglected Tropical Diseases have found that an exam of just a patient's hands, feet and lower legs may have the potential to catch more than 90 percent of all scabies cases, regardless of severity.

28 Dec 2018

Scientists discover two therapies that slow progression of pediatric leukemia in mice

Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the final paper published Dec. 20 in Genes & Development.

24 Dec 2018

Researchers identify hundreds of new genes linked to blindness in lab mice

Hundreds of new genes linked to blindness and other vision disorders have been identified in a screen of mouse strains. Many of these genes are likely important in human vision and the results could help identify new causes of hereditary blindness in patients.

24 Dec 2018

Hospital readmission reduction program associated with increase in post-discharge mortality

A policy designed to reduce hospital readmissions through financial penalties was associated with a significant increase in post-discharge mortality for patients with heart failure and pneumonia, according to a large-scale study by researchers in Beth Israel Deaconess Medical Center's Smith Center for Outcomes Research in Cardiology.

21 Dec 2018

FDA approves new treatment for rare disease of the bone marrow and blood

The U.S. Food and Drug Administration today approved Elzonris (tagraxofusp-erzs) infusion for the treatment of blastic plasmacytoid dendritic cell neoplasm in adults and in pediatric patients, two years of age and older.

21 Dec 2018

Combination of statins and Mediterranean diet more effective in reducing cardiovascular mortality risk

For those who have already had a heart attack or a stroke, the combination of statins and Mediterranean Diet appears to be the most effective choice to reduce the risk of mortality, especially from cardiovascular causes.

21 Dec 2018

Researchers develop artificial intelligence system to diagnose, classify brain hemorrhages

A team of investigators from the Massachusetts General Hospital Department of Radiology has developed a system using artificial intelligence to quickly diagnose and classify brain hemorrhages and to provide the basis of its decisions from relatively small image datasets.

21 Dec 2018

Simple protocol rescues stressed liver cells

Isolated human hepatocytes are essential tools in preclinical and clinical liver research, but cell quality is highly variable. Now, researchers from Uppsala University have devised a simple protocol that improves hepatocyte quality and enables cells from a wider quality spectrum to be used in standard and advanced cell culture. The findings are published in Archives of Toxicology.

21 Dec 2018

Moving from Glass Slides to Whole-Slide Digital Imaging

In this interview conducted at SfN 2018, Susan Tappan explains the benefits of whole slide imaging and how MBF have collaborated with Huron to achieve repeatable whole slide imaging workflows.

From MBF Bioscience 21 Dec 2018

Atmospheric scientists observe effect of aerosols on clouds at the cleanest place in the world

How do airborne particles, so-called aerosols, affect the formation and life cycle of clouds and precipitation? In order to come one step closer to solving this question, atmospheric scientists from the Leibniz Institute for Tropospheric Research and the Leipzig Institute for Meteorology at Leipzig University will observe the atmosphere at one of the cleanest places in the world for at least a year.

21 Dec 2018

Lupus Research Alliance announces 2018 recipients of the Distinguished Innovator Award

The Lupus Research Alliance is proud to announce the 2018 recipients of the Dr. William E. Paul Distinguished Innovator Award in Lupus and Autoimmunity: Nir Hacohen, PhD and Vijay Kuchroo, DVM, PhD. Dr. Hacohen is seeking better ways to treat lupus kidney disease, the major cause of illness and death among patients with lupus.

21 Dec 2018

Micropores in fabricated tissues allow nutrient and oxygen diffusion into core

Micropores in fabricated tissues such as bone and cartilage allow nutrient and oxygen diffusion into the core, and this novel approach may eventually allow lab-grown tissue to contain blood vessels, according to a team of Penn State researchers.

20 Dec 2018

Ultrasensitive test detects corrupted protein associated with Alzheimer's and CTE

An ultrasensitive test has been developed that detects a corrupted protein associated with Alzheimer's disease and chronic traumatic encephalopathy, a condition found in athletes, military veterans, and others with a history of repetitive brain trauma.

20 Dec 2018

New portable optical imaging system brings diagnostic potential into operating room

A team of University of Illinois at Urbana-Champaign researchers led by Professor Stephen Boppart has successfully visualized the tumor microenvironment of human breast tissue shortly after it was surgically removed from a patient in the operating room.

20 Dec 2018

Study lays foundation for addressing unresolved questions in human aging

Doctors have long observed that biological age and chronological age are not always one and the same. A 55-year-old may exhibit many signs of old age and have numerous age-related diseases, whereas an 80-year-old may be healthy and robust.

20 Dec 2018

Laboratory News and Research

Study uncovers how tumors backfire on neoadjuvant chemotherapy

China’s war on air pollution is leading to rise of ozone pollution

Peptide isolated from spirulina extract may counteract arterial hypertension

Sound can affect perception of touch in mice

Genetically diverse mouse models improves usability for precision medicine for Alzheimer's

Speedier examinations may be useful in public health assessments of scabies

Scientists discover two therapies that slow progression of pediatric leukemia in mice

Researchers identify hundreds of new genes linked to blindness in lab mice

Hospital readmission reduction program associated with increase in post-discharge mortality

FDA approves new treatment for rare disease of the bone marrow and blood

Combination of statins and Mediterranean diet more effective in reducing cardiovascular mortality risk

Researchers develop artificial intelligence system to diagnose, classify brain hemorrhages

Simple protocol rescues stressed liver cells

Moving from Glass Slides to Whole-Slide Digital Imaging

Atmospheric scientists observe effect of aerosols on clouds at the cleanest place in the world

Lupus Research Alliance announces 2018 recipients of the Distinguished Innovator Award

Micropores in fabricated tissues allow nutrient and oxygen diffusion into core

Ultrasensitive test detects corrupted protein associated with Alzheimer's and CTE

New portable optical imaging system brings diagnostic potential into operating room

Study lays foundation for addressing unresolved questions in human aging

Viva Saliva Book: The ultimate guide to saliva Book preview Download eBook

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