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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

IDIBELL and IDIPAZ scientists identify epigenetic alterations in CVID

Researchers of the Chromatin and Disease Group from the Bellvitge Biomedical Research Institute and La Paz Hospital have identified epigenetic alterations in Common Variable Immunodeficiency (CVID), the most common primary immunodeficiency, using as a starting point genetically identical monozygotic twins discordant for the disease.

18 Jun 2015

Hitachi High-Technologies, QIAGEN form new strategic partnership to advance molecular testing

Hitachi High-Technologies Corporation and QIAGEN N.V. have entered into a long-term strategic collaboration involving initiatives to deliver important advances in molecular testing.

From QIAGEN Manchester Limited 18 Jun 2015

Genes could help physicians make informed treatment decisions for metastatic colorectal cancer patients

Metastatic colorectal cancer patients tend to live longer when they respond to the first line of chemotherapy their doctors recommend. To better predict how patients will respond to chemotherapy drugs before they begin treatment, researchers at University of California, San Diego School of Medicine conducted a proof-of-principle study with a small group of metastatic colorectal cancer patients.

18 Jun 2015

Simple test could help identify genetically inherited risk for prostate cancer

Men with an elevated, genetically inherited risk for prostate cancer could be routinely identified with a simple blood or urine test, scientists at UC San Francisco and Kaiser Permanente Northern California have concluded, potentially paving the way to better or earlier diagnosis.

18 Jun 2015

Australian researchers discover gene involved in muscular dystrophy

Australian researchers have made a critical discovery about a gene involved in muscular dystrophy that could lead to future therapies for the currently untreatable disease.

18 Jun 2015

Highly efficient ChIP assay kit for FFPE samples

Chromatrap®, a business unit of Porvair Sciences, has introduced a new Formaldehyde Fixed Paraffin-Embedded (FFPE) ChIP Kit which overcomes the widely acknowledged shortfalls of the technique.

From Chromatrap® - Porvair Sciences Ltd 17 Jun 2015

Optimised ChIP protocols for qPCR and sequencing

Chromatrap®, a business unit of Porvair Sciences, has announced a new web page that brings together protocols developed using their proprietary solid state chromatin immunoprecipitation (ChIP) technology.

From Chromatrap® - Porvair Sciences Ltd 17 Jun 2015

Bivalent HPV vaccine efficacy may be independent of dose

Fewer than three doses of the bivalent human papillomavirus vaccine may be sufficient to offer adequate protection against cervical HPV-16 and -18 infection, research published in The Lancet Oncology indicates.

17 Jun 2015

TGen, Phoenix Children's Hospital developing new methods to store and transport blood samples

The Translational Genomics Research Institute and Phoenix Children's Hospital are developing new economical methods of preserving, storing and transporting high-quality blood plasma proteins for use in diagnosing and treating disease.

17 Jun 2015

Researchers reveal that Helicobacter pylori infection can lead to gastric cancer

Around half of the global population is chronically infected with the stomach bacterium Helicobacter pylori, almost 1 percent of whom go on to develop gastric adenocarcinoma, one of the deadliest forms of cancer. Usually it takes many decades for the cancer to develop, making it difficult to pinpoint exactly how it is linked to an infection.

17 Jun 2015

Breakthrough discovery on element transformation could lead to new way for treating cancer with radiation

Chemists at Tufts University's School of Arts and Sciences, collaborating with PerkinElmer and UCL (University College London), have witnessed atoms of one chemical element morph into another for the first time ever -- a feat that produced an unexpected outcome that could lead to a new way to safely treat cancer with radiation.

17 Jun 2015

Researchers assemble full genome of living organism using Oxford Nanopore's MinIONTM device

Researchers in Canada and the U.K. have for the first time sequenced and assembled de novo the full genome of a living organism, the bacteria Escherichia Coli, using Oxford Nanopore's MinIONTM device, a genome sequencer that can fit in the palm of your hand.

17 Jun 2015

CINtec PLUS Cytology test more effective than HC2 HPV test in identifying women with precancerous lesions

Ventana Medical Systems, Inc., a member of the Roche Group, today announced the publication of further results from the Primary ASC-US LSIL Marker Study (PALMS) in this month's issue of Cancer Cytopathology. The PALMS study, which enrolled more than 27,000 women from five European countries, was designed to evaluate the diagnostic performance of the CINtec PLUS Cytology test in detecting pre-cancerous cervical disease compared to HPV testing and more traditional screening methods like Pap cytology.

16 Jun 2015

Althea obtains European GMP certificate from HPRA for commercial aseptic filling and testing

Ajinomoto Althea, Inc., a leading provider of biopharmaceutical contract development and manufacturing services announced today that it has officially received its European GMP certificate from the Health Products Regulatory Authority for commercial aseptic filling and testing.

16 Jun 2015

OncoSec enrolls first patient in Phase II trial of ImmunoPulse IL-12 for treatment of HNSCC

OncoSec Medical Inc., a company developing DNA-based intratumoral cancer immunotherapies, announced today that the company has enrolled the first patient into OMS-I130, a Phase II clinical trial of ImmunoPulse IL-12 in patients with treatment-refractory, metastatic and unresectable squamous cell carcinoma of the head and neck (HNSCC).

16 Jun 2015

UK dermatologist explains the facts on vitamin D and sun exposure

Sometimes it can be hard to weigh up the benefits of vitamin D versus sun exposure. We talk to Dr Anjali Mahto, Consultant Dermatologist & British Skin Foundation Spokesperson who explains.

16 Jun 2015

Scientists develop new technique to analyze bacterial populations

Scientists from the Icahn School of Medicine at Mount Sinai have developed a new technique to more precisely analyze bacterial populations, to reveal epigenetic mechanisms that can drive virulence. The new methods hold the promise of a potent new tool to offset the growing challenge of antibiotic resistance by bacterial pathogens.

16 Jun 2015

Scientists find way to accelerate wound healing in diabetic mice

One of the body's own tools for preventing wound infections may actually interfere with wound healing, according to new research from Boston Children's Hospital. In a study published online in Nature Medicine, scientists from the hospital's Program in Cellular and Molecular Medicine found they could speed up wound healing in diabetic mice by keeping immune cells called neutrophils from producing bacteria-trapping neutrophil extracellular traps (NETs).

15 Jun 2015

Better way to predict survival in patients with HPV-positive oropharyngeal cancer

According to Sturgis, the incidence of HPV-positive oropharyngeal carcinoma has increased dramatically in recent years. Although patients with HPV-positive disease have a better prognosis than those with HPV-negative disease, researchers are still seeking a better understanding of what group of patients is more likely to respond to treatment.

15 Jun 2015

Taiho, Servier sign exclusive license agreement to develop and commercialize TAS-102 drug

Taiho Pharmaceutical Co., Ltd.(Japan) and Servier (France) announced on June 15 that they have entered into an exclusive license agreement on June 12, 2015 for the development and commercialization of TAS-102 (nonproprietary names: trifluridine and tipiracil hydrochloride) in Europe and other countries.

15 Jun 2015

DNA News and Research

Further Reading

IDIBELL and IDIPAZ scientists identify epigenetic alterations in CVID

Hitachi High-Technologies, QIAGEN form new strategic partnership to advance molecular testing

Genes could help physicians make informed treatment decisions for metastatic colorectal cancer patients

Simple test could help identify genetically inherited risk for prostate cancer

Australian researchers discover gene involved in muscular dystrophy

Highly efficient ChIP assay kit for FFPE samples

Optimised ChIP protocols for qPCR and sequencing

Bivalent HPV vaccine efficacy may be independent of dose

TGen, Phoenix Children's Hospital developing new methods to store and transport blood samples

Researchers reveal that Helicobacter pylori infection can lead to gastric cancer

Breakthrough discovery on element transformation could lead to new way for treating cancer with radiation

Researchers assemble full genome of living organism using Oxford Nanopore's MinIONTM device

CINtec PLUS Cytology test more effective than HC2 HPV test in identifying women with precancerous lesions

Althea obtains European GMP certificate from HPRA for commercial aseptic filling and testing

OncoSec enrolls first patient in Phase II trial of ImmunoPulse IL-12 for treatment of HNSCC

UK dermatologist explains the facts on vitamin D and sun exposure

Scientists develop new technique to analyze bacterial populations

Scientists find way to accelerate wound healing in diabetic mice

Better way to predict survival in patients with HPV-positive oropharyngeal cancer

Taiho, Servier sign exclusive license agreement to develop and commercialize TAS-102 drug

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