Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

New ultrasound technique shows great promise in detecting breast cancer

A new ultrasound technique can help distinguish benign breast tumors from malignant ones. The technology was developed with support from the Swiss National Science Foundation.

30 Oct 2018

Forced expression of a natural protein reduces fat in mice by a third

In a mouse model of obesity, forced expression of the protein FGFBP3 (BP3 for short) significantly reduced the animals’ fat mass.

29 Oct 2018

Natural protein may offer novel therapy to reverse disorders associated with metabolic syndrome

To the great surprise of cancer researchers, a protein they investigated for its possible role in cancer turned out to be a powerful regulator of metabolism.

29 Oct 2018

Novartis enters into clinical development agreement with Pfizer to improve treatment of NASH

Novartis announced today that it has entered into a clinical development agreement with Pfizer which will include a study combining tropifexor and one or more Pfizer compounds for the treatment of NASH, including an Acetyl CoA-Carboxylase (ACC) Inhibitor (PF-05221304, a Diacylglycerol O-Acyltransferase 2 (DGAT2) Inhibitor (PF-06865571, and a Ketohexokinase (KHK) Inhibitor (PF-06835919).

29 Oct 2018

Researchers identify new potential target to inhibit progression of liver disease

Naglaa Shoukry, Ph. D., and her team have made a significant breakthrough in their research aiming to limit the progression of liver disease.

26 Oct 2018

Head and neck cancer survivors more likely to commit suicide

Despite improved survival rates among cancer patients, the risk of death by suicide remains high, especially among those treated for head and neck cancers.

25 Oct 2018

Combination therapy enhances wound healing

By incorporating a gene-suppressing drug into an over-the-counter gel, researchers at Albert Einstein College of Medicine and their colleagues cut healing time by half and significantly improved healing outcomes compared to control treatments.

25 Oct 2018

Alcohol changes the molecular basis of memory formation

A new study has shown how alcohol consumption fuels addiction by hijacking a conserved memory pathway in the brain and changing memory formation.

25 Oct 2018

Researchers find improvement in liver transplant survival rate among older recipients

An increasing number of older adults are diagnosed with end-stage liver disease. End-stage liver disease is a life-threatening condition in which the liver stops working normally.

23 Oct 2018

Map of human liver cells reveals molecular make-up of individual cells

A map of the cells in the human liver has been created by University Health Network Transplant Program and University of Toronto researchers, revealing for the first time differences between individual cells at the molecular level which can have a profound impact on their behaviour in tissue, tumours and disease.

From 10x Genomics, Inc. 23 Oct 2018

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

With a pair of RO1 grants from the National Institutes of Health, pain researcher Daniela Salvemini, Ph.D., will embark on two new research projects, studying chemotherapy-induced cognitive impairment, or "chemo brain," symptoms and unwanted side effects of opioids.

23 Oct 2018

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

UT Southwestern biochemist Dr. Zhijian "James" Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body's immune defense against infections and cancers.

19 Oct 2018

Study reports increased risk of death in children with inflammatory bowel disease

Children who develop inflammatory bowel disease (ulcerative colitis or Crohn's disease) have an increased risk of death, both in childhood and later in life, a study from Karolinska Institutet in Sweden published in the journal Gastroenterology reports.

19 Oct 2018

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

With an estimated twenty-thousand protein-coding genes in the human genome, pinpointing a specific gene or pathway responsible for a particular disease can be like finding a needle in the proverbial haystack.

17 Oct 2018

One-time universal screening recommended to tackle increase in hepatitis C

Physicians are encountering a growing number of younger patients who are testing positive for hepatitis C virus fueled largely by the opioid crisis impacting communities around the country.

17 Oct 2018

Study highlights need for increased support for alcohol-related liver disease patients

Two in three ALD patients admitted to an intensive care unit (ICU) survived for less than a year afterwards, the study shows.

15 Oct 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Low levels of cellular copper may make fat cells fatter

In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.

11 Oct 2018

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

Carnegie's Department of Embryology scientist Steven Farber and team have been awarded a 5-year $3.3-million NIH grant to identify novel pharmaceuticals for combatting a host of diseases associated with altered levels of lipoproteins like LDL ("bad cholesterol").

11 Oct 2018

King's College researchers awarded £2.3 million for new trial to treat liver disease

Dr Mark McPhail from the Department of Inflammation Biology, School of Immunology & Microbial Sciences and Dr Vishal Patel from the Institute of Liver Studies at King's College Hospital have been awarded £2.3 million by the National Institute of Health Research Health Technology Assessment to lead a new UK wide multi-centre trial to treat liver disease.

9 Oct 2018

Liver Disease News and Research

Further Reading

New ultrasound technique shows great promise in detecting breast cancer

Forced expression of a natural protein reduces fat in mice by a third

Natural protein may offer novel therapy to reverse disorders associated with metabolic syndrome

Novartis enters into clinical development agreement with Pfizer to improve treatment of NASH

Researchers identify new potential target to inhibit progression of liver disease

Head and neck cancer survivors more likely to commit suicide

Combination therapy enhances wound healing

Alcohol changes the molecular basis of memory formation

Researchers find improvement in liver transplant survival rate among older recipients

Map of human liver cells reveals molecular make-up of individual cells

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

Study reports increased risk of death in children with inflammatory bowel disease

Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer

One-time universal screening recommended to tackle increase in hepatitis C

Study highlights need for increased support for alcohol-related liver disease patients

Metabolome tests could be new way to measure obesity and health

Low levels of cellular copper may make fat cells fatter

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

King's College researchers awarded £2.3 million for new trial to treat liver disease

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