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Skin may help to predict future heart problems

Our skin tells us when we've spent too much time in the sun or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin can also foretell issues unrelated to the protective barrier.

10 Dec 2020

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Could number two be number one when it comes to combating recurrent Clostridium difficile (CDI) infections?Using genetic material analysis and machine learning, UBC researchers have pinpointed several key factors to ensure successful fecal microbiota transplants (FMT), which have proven successful in treating bacterial infections in the gut including illnesses like C. difficile, Crohn's Disease, Colitis and even obesity, explains lead author Negin Kazemian.

10 Dec 2020

The effects of cigarette smoke and COPD on SARS-CoV-2 infection

Researchers have revealed some of the effects of cigarette smoke and chronic obstructive pulmonary disease (COPD) on SARS-CoV-2 infection.

9 Dec 2020

UC Davis Health joins with Novavax to test a new experimental coronavirus vaccine

Despite the encouraging news of potentially successful COVID-19 vaccine trials, there is not yet an FDA-approved vaccine available. Research into other effective coronavirus vaccines continues, including at UC Davis Health.

8 Dec 2020

Researchers find elevated biomarker for blood vessel damage in children with SARS-CoV-2

Researchers at Children's Hospital of Philadelphia have found elevated levels of a biomarker related to blood vessel damage in children with SARS-CoV-2 infection, even if the children had minimal or no symptoms of COVID-19.

8 Dec 2020

Synthetic biology and machine-learning can speed up maturation of lab-grown organ

Researchers at the University of Pittsburgh School of Medicine have combined synthetic biology with a machine-learning algorithm to create human liver organoids with blood- and bile-handling systems. When implanted into mice with failing livers, the lab-grown replacement livers extended life.

8 Dec 2020

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Early study data shows a 29% overall response rate, the favorable safety profile in blastic plasmacytoid dendritic cell neoplasm (BPDCN)

8 Dec 2020

Study: Innate lymphoid cells are involved in many aspects of human health, disease

Children's Hospital Colorado (Children's Colorado) Center for Cancer and Blood Disorders (CCBD) announced today that a study about the manipulation of bone marrow stem cells into innate lymphoid and natural killer cells will be published in Science Immunology, a well-respected, high-impact medical journal.

8 Dec 2020

Study examines effect of low-dose vancomycin to treat clostridium difficile infection

Clostridium difficile infection (CDI) is inflammation of the colon caused by a bacteria called clostridium difficile and is the most common cause of infectious diarrhea in hospitalized patients.

8 Dec 2020

Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.

7 Dec 2020

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).

7 Dec 2020

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer.

7 Dec 2020

Donor stem cell transplant can improve survival rates for older patients with MDS, study shows

A new clinical trial offers the most compelling evidence to date that a donor stem cell transplant can improve survival rates for older patients with higher-risk myelodysplastic syndrome (MDS), Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology Annual Meeting.

5 Dec 2020

UZ Leuven team performs double lung transplant with lungs of an ex-COVID-19 patient

The lung transplantation team at UZ Leuven, the university hospital of Leuven, performed a double lung transplantation for the first time with lungs from a donor who had experienced a mild form of COVID-19 three months earlier.

4 Dec 2020

NMR-based diagnostic tool could be used to detect fatty liver disease or liver fibrosis

About 25 percent of the U.S. population suffers from fatty liver disease, a condition that can lead to fibrosis of the liver and, eventually, liver failure.

2 Dec 2020

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD).

2 Dec 2020

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program.

1 Dec 2020

Gut microbiota directly shapes the makeup of human immune system, shows study

MSK researchers have uncovered an important finding about the relationship between the microbiota and the immune system, showing for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.

1 Dec 2020

Transplant News and Research

Skin may help to predict future heart problems

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

The effects of cigarette smoke and COPD on SARS-CoV-2 infection

UC Davis Health joins with Novavax to test a new experimental coronavirus vaccine

Researchers find elevated biomarker for blood vessel damage in children with SARS-CoV-2

Synthetic biology and machine-learning can speed up maturation of lab-grown organ

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Study: Innate lymphoid cells are involved in many aspects of human health, disease

Study examines effect of low-dose vancomycin to treat clostridium difficile infection

Study highlights previously unknown mechanisms involved in myeloma resistance

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Clonal hematopoiesis can confer a health benefit in allogeneic transplants

Donor stem cell transplant can improve survival rates for older patients with MDS, study shows

UZ Leuven team performs double lung transplant with lungs of an ex-COVID-19 patient

NMR-based diagnostic tool could be used to detect fatty liver disease or liver fibrosis

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Gut microbiota directly shapes the makeup of human immune system, shows study

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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