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Overweight, obese people maintained an average weight loss of 10% with lifestyle changes and medications

A new study finds overweight and obese people maintained an average weight loss of 10.6% over 3 to 5 years with a program of lifestyle changes in combination with anti-obesity medications. Weight loss of more than 10% provides significant health benefits, according to researchers who are presenting their findings Sunday, June 12 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

New analysis reveals direct links between chronic loneliness and mental health distress

New research published today by the Government has identified direct links between chronic loneliness and mental health distress.

13 Jun 2022

Probiotic bacteria may enhance anti-cancer activities of tamoxifen to reduce ER+ breast cancer risk

Probiotic bacteria may enhance anti-cancer activities of the breast cancer drug tamoxifen and other endocrine-targeted therapies, which could help reduce the risk of estrogen receptive positive (ER+) breast cancer, suggests a new study presented Monday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Fezolinetant reduces the frequency and severity of menopausal hot flashes, study finds

Fezolinetant significantly reduced the frequency and severity of moderate-to-severe vasomotor symptoms (VMS), or hot flashes, associated with menopause, according to a Phase 3 industry-sponsored study being presented Saturday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

Spinal posture assessment in health exams reliably detects cognitive decline

A mass survey of citizens aged 50 to 89 years examined whether cognitive decline could be detected by sagittal spinal balance measurement based on a radiological approach.

10 Jun 2022

One in 500 men may carry an extra X or Y chromosome which could increase risk of several diseases

Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis, say researchers at the universities of Cambridge and Exeter.

10 Jun 2022

Nanomaterial-based devices may be a viable option for monitoring, treatment of cardiovascular diseases

Cardiovascular diseases are the leading cause of death across the globe, responsible for about 17.9 million (32%) of all deaths worldwide every year.

10 Jun 2022

New molecule kills a broad spectrum of hard-to-treat cancers

A new molecule synthesized by a University of Texas at Dallas researcher kills a broad spectrum of hard-to-treat cancers, including triple-negative breast cancer, by exploiting a weakness in cells not previously targeted by other drugs.

10 Jun 2022

Early success of shorter tuberculosis treatment in Nigeria could pave the way for nationwide rollout

Early success with Nigeria's implementation of the new and shorter six-month tuberculosis treatment regimen in four states could pave the way for its rollout nationwide, says an expert.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Inhaled vaccines provide better protection and stronger immunity than nasal sprays, study confirms

McMaster University scientists who compared respiratory vaccine-delivery systems have confirmed that inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays.

10 Jun 2022

Older adults with Type 1 diabetes have greater risk for muscle weakening, cardiovascular complications

Older adults with Type 1 diabetes (T1D) are at significantly higher risk of both muscle weakening and cardiovascular complications, say McMaster University researchers.

10 Jun 2022

Using artificial intelligence to discover new antivirals against COVID-19 and future pandemics

Research into drugs to treat mosquito-borne flaviviruses such as Zika and dengue as well as COVID-19will benefit from a major funding boost, says a group of international scientists using artificial intelligence to discover new oral antivirals.

10 Jun 2022

Stress protein in fibroblasts appears to be an attractive cancer drug target

A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

10 Jun 2022

Medicine News and Research

Overweight, obese people maintained an average weight loss of 10% with lifestyle changes and medications

New analysis reveals direct links between chronic loneliness and mental health distress

Probiotic bacteria may enhance anti-cancer activities of tamoxifen to reduce ER+ breast cancer risk

Fezolinetant reduces the frequency and severity of menopausal hot flashes, study finds

New machine learning algorithm finds a gene signature characteristic of tumors

Spinal posture assessment in health exams reliably detects cognitive decline

One in 500 men may carry an extra X or Y chromosome which could increase risk of several diseases

Nanomaterial-based devices may be a viable option for monitoring, treatment of cardiovascular diseases

New molecule kills a broad spectrum of hard-to-treat cancers

Early success of shorter tuberculosis treatment in Nigeria could pave the way for nationwide rollout

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Inhaled vaccines provide better protection and stronger immunity than nasal sprays, study confirms

Older adults with Type 1 diabetes have greater risk for muscle weakening, cardiovascular complications

Using artificial intelligence to discover new antivirals against COVID-19 and future pandemics

Stress protein in fibroblasts appears to be an attractive cancer drug target

Naturally-produced antibodies in mothers may enhance infants' immunity against bacterial pathogens

Deciphering the structure of nuclear pore complex piece by piece

Using a harmless amoeba to protect children from dangerous infections

Creating CAR T cells without an immune brake

Transgender college students more likely to suffer from sleep disorders and mental health issues

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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