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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

PCDx test performs better than FoundationOne test in clinical study

Data from a small cohort published OncoTargets and Therapy today shows that the Paradigm Cancer Diagnostic Test (PCDx) performed better than Foundation Medicine's FoundationOne test across a number of key clinical variables, including turnaround time (TAT) and clinically actionable biomarker targets.

28 Apr 2015

Scientific study confirms harmful effect of submicroscopic malarial infections during pregnancy

A scientific study conducted in Benin by researchers from IRD and the Centre for study and research on pregnancy associated malaria and infancy (CERPAGE, Benin) confirms the harmful impact of submicroscopic malarial infections during pregnancy. These complications include maternal anaemia, premature births and low birthweights in children.

28 Apr 2015

Study shows link between upright locomotion and spinal health

A Simon Fraser University researcher has uncovered what may be the first quantified evidence demonstrating a relationship between upright locomotion and spinal health.

28 Apr 2015

Yale researchers successfully correct gene mutation that causes cystic fibrosis

Yale researchers successfully corrected the most common mutation in the gene that causes cystic fibrosis, a lethal genetic disorder. The study was published April 27 in Nature Communications.

28 Apr 2015

Merrimack completes submission of MM-398 NDA for treatment of post-gemcitabine metastatic pancreatic cancer

Merrimack Pharmaceuticals, Inc. and Baxter International Inc. today jointly announced that Merrimack has completed the rolling submission of the New Drug Application (NDA) for MM-398 (irinotecan liposome injection), also known as "nal-IRI," to the U.S. Food and Drug Administration.

From Baxter International Inc. 27 Apr 2015

ISSCR calls for moratorium on human germline genome editing attempts in clinical practice

In response to an article published by Chinese scientists describing research that used gene editing technologies in human embryos, the International Society for Stem Cell Research has again called for a moratorium on attempts at human clinical germline genome editing while extensive scientific analysis of the potential risks is conducted, along with broad public discussion of the societal and ethical implications.

27 Apr 2015

Scientists discover new way to control inflammation during worm infections and allergies

Research from The University of Manchester is bringing scientists a step closer to developing new therapies for controlling the body's response to allergies and parasitic worm infections.

25 Apr 2015

New method could help scientists spot source of disease-causing mutations in enhancers

A new technique that identifies how genes are controlled could help scientists spot errors in the genetic code which trigger disease, a study suggests.

25 Apr 2015

Natera, LifeLabs sign new agreement for non-invasive prenatal testing in Canada

Natera, Inc., a global leader in non-invasive genetic testing, and LifeLabs Medical Laboratory Services today announced a new agreement that gives LifeLabs the rights to perform non-invasive prenatal testing (NIPT) in Canada using Natera technology.

From Natera 25 Apr 2015

Penn researchers find molecular bond between DNA damage, cellular senescence and premature aging

Like a beloved pair of jeans, human DNA accumulates damage over time, and older people's bodies can't repair it as well. Many scientists believe a build up of damage can cause cells to enter an irreversible dormant state known as senescence. Cellular senescence is believed to be responsible for some of the telltale signs of aging, such as weakened bones, less resilient skin and slow-downs in organ function.

24 Apr 2015

EMD Millipore launches Magna ChIRP RNA Interactome Kits for analyzing chromatin-associated RNAs

EMD Millipore, the Life Science business of Merck KGaA of Darmstadt, Germany, today introduced Magna ChIRP™ RNA Interactome Kits, which allow researchers to more easily identify, recover and analyze regions of chromatin that interact with chromatin-associated RNAs such as long non-coding RNA (lncRNA).

23 Apr 2015

Epigenetic processes influence children's later ability to learn and cognitive performance

Although it is now widely recognised that a poor start to life has long-term effects on a child's later ability to learn, the mechanisms by which the environment in early life affects later life chances are poorly understood.

23 Apr 2015

Scientists find genetic link between autism and prodigy

Researchers have uncovered the first evidence of a genetic link between prodigy and autism. The scientists found that child prodigies in their sample share some of the same genetic variations with people who have autism.

23 Apr 2015

AMP report provides overview of current research on minimally invasive 'liquid biopsy' approaches

The Association for Molecular Pathology, the premier global, non-profit organization serving molecular diagnostic professionals, today published a special article in The Journal of Molecular Diagnostics titled, "Do Circulating Tumor Cells, Exosomes, and Circulating Tumor Nucleic Acids Have Clinical Utility?" The report provides a thorough overview of research to-date on the minimally invasive "liquid biopsy" approaches to cancer diagnostics.

23 Apr 2015

Purdue University study sheds light on how decitabine drug reverses cell damage

A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to treatment.

23 Apr 2015

New patent-pending detection method identifies bacteria contaminating oysters

In a major breakthrough in shellfish management and disease prevention, researchers at the University of New Hampshire have discovered a new method to detect a bacterium that has contaminated New England oyster beds and sickened consumers who ate the contaminated shellfish.

23 Apr 2015

IDT’s San Diego, California, manufacturing facility receives ISO 14001 certification

Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, has announced that its San Diego, California, manufacturing facility has attained ISO 14001:2004 certification for its environmental management systems. Now, both of IDT’s US manufacturing sites (Coralville, IA and San Diego, CA) have ISO 14001 certified environmental management systems.

From Integrated DNA Technologies 22 Apr 2015

Sysmex Inostics to offer OncoBEAM CLIA laboratory services in Germany, Austria and Switzerland

Sysmex Inostics, a subsidiary of Sysmex Corporation, today announced that they have signed an exclusive distributor agreement with IndivuTest GmbH, and its parent company Indivumed GmbH, a cancer research company focused on the development of individualized cancer diagnostics and therapies.

From Sysmex America, Inc. 22 Apr 2015

Researchers provide new clues, mechanisms to understand functions of 'rebel' DNA in cancer

Genes usually always be expressed as in Western writing: from left to right on the white canvas of our DNA. So when we speak of the activity of our genome, in fact we are referring to the expression of genes in this sense of the double-stranded DNA.

22 Apr 2015

Researchers uncover methylated DNA markers that may lead to noninvasive cancer screening

A team of Mayo Clinic researchers has succeeded in identifying the source of cancer in patients' gastrointestinal tracts by analyzing DNA markers from tumors. The results open the possibility that doctors could one day be able to screen for cancer anywhere in the body with a noninvasive blood test or stool sample.

22 Apr 2015

DNA News and Research

Further Reading

PCDx test performs better than FoundationOne test in clinical study

Scientific study confirms harmful effect of submicroscopic malarial infections during pregnancy

Study shows link between upright locomotion and spinal health

Yale researchers successfully correct gene mutation that causes cystic fibrosis

Merrimack completes submission of MM-398 NDA for treatment of post-gemcitabine metastatic pancreatic cancer

ISSCR calls for moratorium on human germline genome editing attempts in clinical practice

Scientists discover new way to control inflammation during worm infections and allergies

New method could help scientists spot source of disease-causing mutations in enhancers

Natera, LifeLabs sign new agreement for non-invasive prenatal testing in Canada

Penn researchers find molecular bond between DNA damage, cellular senescence and premature aging

EMD Millipore launches Magna ChIRP RNA Interactome Kits for analyzing chromatin-associated RNAs

Epigenetic processes influence children's later ability to learn and cognitive performance

Scientists find genetic link between autism and prodigy

AMP report provides overview of current research on minimally invasive 'liquid biopsy' approaches

Purdue University study sheds light on how decitabine drug reverses cell damage

New patent-pending detection method identifies bacteria contaminating oysters

IDT’s San Diego, California, manufacturing facility receives ISO 14001 certification

Sysmex Inostics to offer OncoBEAM CLIA laboratory services in Germany, Austria and Switzerland

Researchers provide new clues, mechanisms to understand functions of 'rebel' DNA in cancer

Researchers uncover methylated DNA markers that may lead to noninvasive cancer screening

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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