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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

BMC pathologists develop protocols for processing, preserving forensic evidence

Boston Medical Center pathologists have developed a set of protocols for processing and preserving forensic evidence, such as shrapnel, bullets and other projectiles, in surgical specimens (i.e. amputated limbs, injured organs, etc.) after a terrorist attack based on lessons learned from the Boston Marathon bombing.

22 Apr 2015

Men with prostate cancer benefit from BRCA-targeting drug

Men with prostate cancer benefit from treatment with the pioneering drug olaparib - the first cancer drug to target inherited mutations - according to the results of a major trial presented today (Tuesday).

22 Apr 2015

Data presented at AACR 2015 recognizes value of EKF PointMan technology for assessing lung cancer mutation status

The PointMan EGFR DNA enrichment kit, a novel method for selective amplification of genotype specific sequences.

From EKF Diagnostics 21 Apr 2015

New clinical utility data for Guardant360 platform to be presented at 2015 AACR Annual Meeting

Guardant Health today announced new clinical utility data for its Guardant360 platform, which will be presented at the 2015 American Association for Cancer Research (AACR) Annual Meeting in Philadelphia.

21 Apr 2015

Smoking and genetics can increase women's likelihood of giving birth to twins

African American mothers who smoke and have a genetic profile that includes a single nucleotide polymorphism (SNP) of the TP53 gene have an increased likelihood of having twins, concluded a team of researchers from the University of South Florida and the University of Illinois at Urbana-Champaign.

21 Apr 2015

Allele-specific lncRNA regulates cancer metabolism

Long non-coding RNAs (lncRNA) are unusual in that they don't encode proteins like normal RNA. Yet they do play a role in regulating cellular functions and interest cancer researchers.

21 Apr 2015

New CUMC study finds DNA anomalies in kids with chronic kidney disease

A significant proportion of children with chronic kidney disease (CKD) have unsuspected chromosomal imbalances, including DNA anomalies that have been linked to neurocognitive disorders, according to a new Columbia University Medical Center study.

21 Apr 2015

TERT gene alterations co-occur with frequently altered bladder cancer genes

In results presented today at the American Association for Cancer Research Annual Meeting 2015, a collaborative study by the University of Colorado Cancer Center and the National Cancer Institute reports that the TERT gene promoter was altered in 69 percent of 54 cases of bladder cancer due to variants that occur after birth (called "somatic") and in 56 percent of bladder cancers due to inherited variants (called "germline").

21 Apr 2015

Global changes in cancer cells' epigenome may determine disease progression

Genomic studies have illuminated the ways in which malfunctioning genes can drive cancer growth while stunting the therapeutic effects of chemotherapy and other treatments. But new findings from Weill Cornell Medical College investigators indicate that these genes are only partly to blame for why treatment that was at one point effective ultimately fails for about 40 percent of patients diagnosed with the most common form of non-Hodgkin Lymphoma.

21 Apr 2015

Latest genome sequencing techniques help identify new autoimmune syndrome in children

Using the latest genome sequencing techniques, a research team led by scientists from UC San Francisco, Baylor College of Medicine, and Texas Children's Hospital has identified a new autoimmune syndrome characterized by a combination of severe lung disease and arthritis that currently has no therapy.

21 Apr 2015

New Dream Team dedicated to ovarian cancer research formed at AACR Annual Meeting 2015

Stand Up To Cancer, Ovarian Cancer Research Fund, Ovarian Cancer National Alliance, and National Ovarian Cancer Coalition, along with the American Association for Cancer Research, Scientific Partner to SU2C, announced today the formation of a Dream Team devoted to ovarian cancer research at the AACR Annual Meeting 2015, held here April 18-22.

21 Apr 2015

AACR throws spotlight on the experience of Individualized Molecular Pancreatic Cancer Therapy trial

After performing thousands of unsuccessful experiments in his attempt to perfect the light bulb, Thomas Edison famously remarked: "I have not failed, not once. I've discovered ten thousand ways that don't work."

21 Apr 2015

Paradigm to provide PCDx test to oncologists in TD2 networks

Paradigm and Translational Drug Development today announced a partnership under which Paradigm will provide their PCDx test to TD2's affiliated oncology provider networks.

20 Apr 2015

Researchers reveal the precise mechanism used by bacteria to target invading viruses

One of the immune system's most critical challenges is to differentiate between itself and foreign invaders -- and the number of recognized autoimmune diseases, in which the body attacks itself, is on the rise.

17 Apr 2015

Donald S. Coffey to receive Margaret Foti Award at AACR Annual Meeting 2015

Donald S. Coffey, PhD, will be honored with the ninth annual American Association for Cancer Research Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

17 Apr 2015

Patterns of DNA anomalies can predict outcomes in women with ovarian cancer

Nearly anyone touched by ovarian cancer will tell you: it's devastating. It's bad enough that cancer in almost 80 percent of patients reaches advanced stages before diagnosis, and that most patients are expected to die within five years. But just as painfully, roughly one quarter of women diagnosed have no warning that they are resistant to platinum-based chemotherapy, the main line of defense, nor that they will likely have 18 months to live.

16 Apr 2015

UAB research findings may lead to better treatment for women with HER2+ breast cancer

There are five subtypes of breast cancer, and they are distinct diseases with vastly different biologies that drastically alter their progression and responses to treatment. Understanding those differences is the starting point to a more effective, personalized treatment of breast cancer, which strikes more than 230,000 women in the U.S. each year.

16 Apr 2015

Research findings could bolster efforts to develop next gen of anti-viral treatments

A newly developed spectroscopy method is helping to clarify the poorly understood molecular process by which an anti-HIV drug induces lethal mutations in the virus's genetic material.

16 Apr 2015

Autophagy: A new approach to fighting tuberculosis

A new approach to combatting tuberculosis would take advantage of a complex, natural process called autophagy that the human body uses to recycle nutrients, remove damaged cell components, eliminate invading bacteria, and respond to inflammation.

16 Apr 2015

New UV light method could help stop spread of hospital superbugs

Can a robot clean a hospital room just as well as a person? According to new research out of the Texas A&M Health Science Center College of Medicine, that is indeed the case. Chetan Jinadatha, M.D., M.P.H., assistant professor at the Texas A&M College of Medicine and chief of infectious diseases at the Central Texas Veterans Health Care System in Temple, is studying the effectiveness of a germ-zapping robot to clean hospital rooms, which could hold the key to preventing the spread of "superbugs" - in turn, saving countless dollars and, most importantly, lives.

15 Apr 2015

DNA News and Research

Further Reading

BMC pathologists develop protocols for processing, preserving forensic evidence

Men with prostate cancer benefit from BRCA-targeting drug

Data presented at AACR 2015 recognizes value of EKF PointMan technology for assessing lung cancer mutation status

New clinical utility data for Guardant360 platform to be presented at 2015 AACR Annual Meeting

Smoking and genetics can increase women's likelihood of giving birth to twins

Allele-specific lncRNA regulates cancer metabolism

New CUMC study finds DNA anomalies in kids with chronic kidney disease

TERT gene alterations co-occur with frequently altered bladder cancer genes

Global changes in cancer cells' epigenome may determine disease progression

Latest genome sequencing techniques help identify new autoimmune syndrome in children

New Dream Team dedicated to ovarian cancer research formed at AACR Annual Meeting 2015

AACR throws spotlight on the experience of Individualized Molecular Pancreatic Cancer Therapy trial

Paradigm to provide PCDx test to oncologists in TD2 networks

Researchers reveal the precise mechanism used by bacteria to target invading viruses

Donald S. Coffey to receive Margaret Foti Award at AACR Annual Meeting 2015

Patterns of DNA anomalies can predict outcomes in women with ovarian cancer

UAB research findings may lead to better treatment for women with HER2+ breast cancer

Research findings could bolster efforts to develop next gen of anti-viral treatments

Autophagy: A new approach to fighting tuberculosis

New UV light method could help stop spread of hospital superbugs

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

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Automating research - solutions and best practices

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