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Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

When scientists transplanted the gut microbes of aged mice into young "germ-free" mice -; raised to have no gut microbes of their own -; the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans.

10 Jun 2024

Host RNA incorporation linked to chronic hepatitis E infection

If the virus incorporates host genetic segments into its genome, the infection may become chronic.

10 Jun 2024

Abnormal aortic blood in the aorta flow linked to vessel wall inflammation and breakdown

Abnormal blood flow in the aorta is linked to inflammation and breakdown of the vessel wall in conditions where the aorta is dilated.

10 Jun 2024

New brain connectivity model predicts dementia years before diagnosis

Whether the default-mode network (DMN) effective connectivity can predict future dementia diagnosis at the individual level.

10 Jun 2024

Evening exercise most effective in reducing blood sugar levels for overweight and obese adults

New research reveals that moderate to vigorous physical activity in the evening for sedentary adults with overweight and obesity is most beneficial in lowering daily blood sugar levels, according to a study published in Obesity, The Obesity Society's (TOS) flagship journal.

10 Jun 2024

Vigorous exercise linked to lower dementia risk in hypertensive individuals

The effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia.

10 Jun 2024

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

Vigorous exercise lowers dementia risk in hypertensive adults, study finds

People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study from researchers at Wake Forest University School of Medicine suggests that engaging in vigorous physical activity more than once a week can lower that risk.

7 Jun 2024

Xylitol linked to higher risk of cardiovascular events, Cleveland Clinic study finds

Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.

7 Jun 2024

How nanoparticles alter blood vessel formation in the womb

Human life begins with a single egg cell that grows into a human being with trillions of cells.

7 Jun 2024

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

In a clinical trial conducted by Stanford Medicine investigators and their colleagues, a 15-day course of Paxlovid -; an antiviral drug combination targeting SARS-CoV-2, the virus that causes COVID-19 -; proved safe as an extended-duration treatment but didn't lessen select symptoms of the syndrome known as long COVID: the persistence, or reappearance, of COVID-related symptoms three months or more after an initial COVID-19 infection.

7 Jun 2024

Critical role of protein-lipid interactions in mitochondrial energy production revealed

By studying mutations in yeast and human cells, Johns Hopkins Medicine scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

7 Jun 2024

How increased mTOR activity shortens lifespan and promotes aging-related diseases

The reality of a population who is aging at an accelerated rate makes it a priority to understand what happens in the body over time, on a molecular scale.

7 Jun 2024

New antioxidant biomaterial may provide relief to people living with chronic pancreatitis

Northwestern University researchers have developed a new antioxidant biomaterial that someday could provide much-needed relief to people living with chronic pancreatitis.

7 Jun 2024

Understanding cancer progression through noninvasive two-color "diffuse in vivo flow cytometry"

In the relentless fight against cancer, a new technology promises to shed light on how we track and understand the spread of this disease within the body.

7 Jun 2024

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

Clinton Mathias, associate professor of nutritional sciences in the College of Agriculture, Health and Natural Resources (CAHNR), has discovered a potential new treatment for allergic reactions.

7 Jun 2024

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Pre-clinical trials: A new therapeutic approach for the severe condition uses modified viruses to replace a missing protein in the brain.

7 Jun 2024

Study reveals mechanism behind brain's response to oxygen deprivation and memory loss

When we learn something new, our brain cells (neurons) communicate with each other through electrical and chemical signals.

7 Jun 2024

New biological mechanism uncovered for treating breast cancer metastasis to the brain

A study led by researchers from the University of Arizona Cancer Center at UArizona Health Sciences identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain.

7 Jun 2024

Gene therapy trial: restored hearing in children with hereditary deafness

The safety and effectiveness of binaural adeno-associated virus 1 (AAV1)-human otoferlin (hOTOF) therapy in five children with autosomal recessive deafness 9 (DFNB9).

7 Jun 2024

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Blood News and Research

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

Host RNA incorporation linked to chronic hepatitis E infection

Abnormal aortic blood in the aorta flow linked to vessel wall inflammation and breakdown

New brain connectivity model predicts dementia years before diagnosis

Evening exercise most effective in reducing blood sugar levels for overweight and obese adults

Vigorous exercise linked to lower dementia risk in hypertensive individuals

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Vigorous exercise lowers dementia risk in hypertensive adults, study finds

Xylitol linked to higher risk of cardiovascular events, Cleveland Clinic study finds

How nanoparticles alter blood vessel formation in the womb

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

Critical role of protein-lipid interactions in mitochondrial energy production revealed

How increased mTOR activity shortens lifespan and promotes aging-related diseases

New antioxidant biomaterial may provide relief to people living with chronic pancreatitis

Understanding cancer progression through noninvasive two-color "diffuse in vivo flow cytometry"

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Study reveals mechanism behind brain's response to oxygen deprivation and memory loss

New biological mechanism uncovered for treating breast cancer metastasis to the brain

Gene therapy trial: restored hearing in children with hereditary deafness

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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