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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Scientists identify mutations in 11 genes associated with aggressive forms of prostate cancer

An international research team led by scientists in the Center for Genetic Epidemiology at the Keck School of Medicine of USC and USC Norris Comprehensive Cancer Center has singled out mutations in 11 genes that are associated with aggressive forms of prostate cancer.

21 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

Rice engineers develop split gene-editing tool with enhanced control

To make a gene-editing tool more precise and easier to control, Rice University engineers split it into two pieces that only come back together when a third small molecule is added.

21 Sep 2023

Brazilian fruits positively impact gut health and chronic disease prevention

The influence of Brazilian native fruits and their by-products on human intestinal microbiota.

21 Sep 2023

Cracking syphilis code: Genome sequencing reveals transmission secrets

Using whole genome sequencing, a new Lancet Microbe study sheds light on syphilis transmission dynamics in England. The research identifies distinct transmission clusters, revealing the effectiveness of genomic data in tracking and intervening in syphilis outbreaks.

20 Sep 2023

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Hyperdiploidy is a genetic condition observed in cancer cells, where the cells contain more chromosomes than usual.

20 Sep 2023

Creating CAR-T cells with enhanced immune memory to fight cancer

Among available immunotherapies, the use of «CAR-T» cells is proving extremely effective against certain blood cancers, but only in half of patients.

20 Sep 2023

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

In a collaborative study published in The Lancet Microbe, the team of scientists, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and WEHI (Walter and Eliza Hall Institute of Medical Research), revealed MPXV-CRISPR – a powerful diagnostic tool capable of detecting MPXV in clinical samples with acute precision and at a faster rate than any other method, thanks to the power of CRISPR technology.

20 Sep 2023

Innovations in baculovirus–insect cell expression systems

The baculovirus–insect cell expression system—insect cells used in conjunction with the baculovirus expression vector system (BEVS)— remains a crucial technology for manufacturing large and complex proteins. This eukaryotic expression system offers inherent safety, ease of scale-up, flexible product design, and versatility for a broad range of proteins.

From Sino Biological Inc. 20 Sep 2023

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Researchers developed a point-of-care assay for the rapid detection of mpox virus.

20 Sep 2023

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

Researchers evaluated sensitivity to immune checkpoint blockade (ICB) therapy.

20 Sep 2023

Lack of clean water, sanitation, and hygienic controls in Cambodia promotes emergence of drug-resistant E. coli

A new study suggests that Escherichia coli and other disease-causing microbes are passing easily between humans and animals in Cambodia, a country where clean water, sanitation and hygienic controls are lacking in many regions.

19 Sep 2023

DeepMind develops new tool to predict pathogenicity of missense variants

DeepMind is releasing AlphaMissense, a tool researchers can use to learn more about the effects that missense mutations – which make up the majority of "variants of uncertain significance" – have on disease.

19 Sep 2023

Scientists uncover potential key risk factors for melanomas in children and adolescents

A recent eBioMedicine study found key risk factors associated with the development of melanoma in children and adolescents.

19 Sep 2023

Coffee, fiber, and the Mediterranean diet are key players in fighting nonalcoholic fatty liver disease

Dietary patterns, foods, and nutrients to ameliorate nonalcoholic fatty liver disease (NAFLD).

19 Sep 2023

Adaptive platform trial shows promise for finding new glioblastoma therapies

An innovative phase 2 clinical trial led by Dana-Farber Cancer Institute in collaboration with 10 major brain tumor centers around the country and designed to find new potential treatments for glioblastoma has reported initial results in the Journal of Clinical Oncology. While none of the three therapeutics tested so far improved overall survival of patients, this adaptive platform trial, the first of its kind in neuro-oncology, has the potential to rapidly and efficiently identify therapies that benefit patients.

19 Sep 2023

New research offers insight about the reason mitochondrial DNA is maternally inherited

New research provides insight about the bedrock scientific principle that mitochondrial DNA -; the distinct genetic code embedded in the organelle that serves as the powerplant of every cell in the body -; is exclusively passed down by the mother.

19 Sep 2023

Hospital wastewater teeming with antibiotic-resistant genes, poses infection risk

Researchers from the UK and the Republic of Ireland have found high levels of antibiotic-resistant genes in the wastewater system of a major teaching hospital. The findings underscore the urgent need for regular decontamination and more stringent infection control measures to protect patients.

19 Sep 2023

Can your baby's gut bacteria predict food allergies?

Researchers in Italy delve into how changes in gut microbiota during the first 1000 days of life can influence the onset of food allergies in children. The study sheds light on various factors such as birth methods, breastfeeding, and antibiotic use that impact gut health, highlighting the need for more research on effective interventions for allergy prevention.

18 Sep 2023

Researchers identify a rare cause of male infertility and discover a potential cure

Researchers investigated the genetic underpinning of asthenozoospermia, the leading cause of male fertility.

18 Sep 2023

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DNA News and Research

Further Reading

Scientists identify mutations in 11 genes associated with aggressive forms of prostate cancer

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

Rice engineers develop split gene-editing tool with enhanced control

Brazilian fruits positively impact gut health and chronic disease prevention

Cracking syphilis code: Genome sequencing reveals transmission secrets

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Creating CAR-T cells with enhanced immune memory to fight cancer

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

Innovations in baculovirus–insect cell expression systems

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

Lack of clean water, sanitation, and hygienic controls in Cambodia promotes emergence of drug-resistant E. coli

DeepMind develops new tool to predict pathogenicity of missense variants

Scientists uncover potential key risk factors for melanomas in children and adolescents

Coffee, fiber, and the Mediterranean diet are key players in fighting nonalcoholic fatty liver disease

Adaptive platform trial shows promise for finding new glioblastoma therapies

New research offers insight about the reason mitochondrial DNA is maternally inherited

Hospital wastewater teeming with antibiotic-resistant genes, poses infection risk

Can your baby's gut bacteria predict food allergies?

Researchers identify a rare cause of male infertility and discover a potential cure

eBook: A guide to RNA sequencing eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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