Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

CARE consortium launches to accelerate drug discovery and development for COVID-19

CARE a new consortium supported by the Innovative Medicines Initiative public-private partnership announced its launch today to accelerate the discovery and development of urgently needed medicines to treat SARS-CoV-2, the virus that causes COVID-19.

19 Aug 2020

Promega introduces new serological antibody test for COVID-19

Promega Corporation today announced the launch of its new serological antibody test for COVID-19 to detect the presence of antibodies against the SARS-CoV-2 virus.

From Promega Corporation 13 Aug 2020

Thermo Fisher Scientific launches two breakthrough imaging filters that take cryo-EM to a new level

Thermo Fisher Scientific, the world leader in serving science, today introduced two breakthrough imaging filters, the Thermo Scientific Selectris Imaging Filter and the Thermo Scientific Selectris X Imaging Filter, taking cryo-electron microscopy to a new level, making it possible to view proteins at true atomic resolution.

From Thermo Fisher Scientific Inc. 13 Aug 2020

UH researcher receives $2.2 million NIH grant to prevent obesity-induced cardiovascular diseases

In the early stages of obesity, endothelial cells - located in the inner layer of the arteries - become dysfunctional and lose their normal protective abilities.

12 Aug 2020

Machine learning helps detect new potential drugs to treat COVID-19

Scientists at the University of California, Riverside, have used machine learning to identify hundreds of new potential drugs that could help treat COVID-19, the disease caused by the novel coronavirus, or SARS-CoV-2.

12 Aug 2020

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

Organocatalysts consisting of organic compounds without metal elements are receiving much attention as next generation catalysts in the hope of reducing environmental burden and coping with exhaustion/rising prices of rare metals.

12 Aug 2020

New technology could serve as more reliable model of amyotrophic lateral sclerosis

A new study published today demonstrates that a technology developed at the University of Central Florida could serve as a more reliable clinically-based model of amyotrophic lateral sclerosis (ALS) and a better screening tool for novel therapies than currently use preclinical models.

12 Aug 2020

Focusing on human enzymes and not SARS-CoV-2 could help treat COVID-19

Now, breakthrough research into malaria suggests targeting enzymes from the human host, rather than from the pathogen itself. The new research could pave the way for effective treatments for a wide range of infectious diseases, including the coronavirus disease (COVID-19).

11 Aug 2020

Using medieval medicine to find new treatments for modern-day infections

News-Medical spoke to researchers from the University of Warwick about their research investigating natural antimicrobials and their potential as antibiotics.

11 Aug 2020

Rice engineers use gene editing to facilitate drug discovery based on natural fungus

Rice University scientists have won federal support for their pursuit of novel drugs to treat human disease.

10 Aug 2020

New process could fast track antiviral and anticancer drug discovery

Discovering antiviral and anticancer drugs will soon be faster and cheaper thanks to new research from Simon Fraser University chemist Robert Britton and his international team.

7 Aug 2020

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

A patient-specific tumor organoid model is being used to identify the most effective chemotherapy protocol to treat appendix and colon tumors, a personalized medicine approach that is showing promise.

7 Aug 2020

High concentrations of toxic pollutants were detected in stranded whales, dolphins

A study led by researchers at Florida Atlantic University's Harbor Branch Oceanographic Institute examined toxins in tissue concentrations and pathology data from 83 stranded dolphins and whales along the southeastern coast of the United States from 2012 to 2018.

7 Aug 2020

UArizona researcher aims to deliver statins effectively into the brain of stroke patients

Every year in the United States, about 800,000 people experience a stroke. Many are left with neurological complications such as paralysis on one side of the body, speech and language problems, vision issues, behavioral changes, and memory loss.

6 Aug 2020

Sanford Burnham Prebys receives NIH grant to identify new therapies for mental disorders

Sanford Burnham Prebys Medical Discovery Institute has been awarded a $4.5 million grant from the National Institutes of Health (NIH) to identify new therapies for mental health disorders.

6 Aug 2020

3D organoid model helps better understand how tumor grows in natural microenvironment

Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have biofabricated human colorectal cancer miniature organs, called organoids, to better understand how a tumor grows in its natural microenvironment and its response to therapies.

5 Aug 2020

Sterile deep well plates

Porvair Sciences offers an extensive range of sterile deep well microplates for sensitive biological and drug discovery applications.

From Porvair Sciences Limited 4 Aug 2020

Artificial intelligence can increase effectiveness of drug repurposing for psychiatric disorders

Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry.

3 Aug 2020

Harbour BioMed and Viva Biotech announce strategic collaboration to promote incubation of biotech startups

Harbour BioMed, a global clinical stage biopharmaceutical company and Viva Biotech (Shanghai) Ltd., a world-leading structure-based drug discovery platform today announced a strategic partnership under which both parties will collate their respective expertise in drug discovery and development to promote the incubation of innovative biotech startups.

31 Jul 2020

First 3D multicellular brain organoid can screen drugs to control inflammation

The scientists who developed the first 3D multicellular brain organoid with a functional blood brain barrier now report that the model could be a promising platform to screen drugs that could work to control inflammation, which is at the center of many neurological conditions, like ischemic stroke.

30 Jul 2020

Drug Discovery News and Research

Further Reading

CARE consortium launches to accelerate drug discovery and development for COVID-19

Promega introduces new serological antibody test for COVID-19

Thermo Fisher Scientific launches two breakthrough imaging filters that take cryo-EM to a new level

UH researcher receives $2.2 million NIH grant to prevent obesity-induced cardiovascular diseases

Machine learning helps detect new potential drugs to treat COVID-19

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

New technology could serve as more reliable model of amyotrophic lateral sclerosis

Focusing on human enzymes and not SARS-CoV-2 could help treat COVID-19

Using medieval medicine to find new treatments for modern-day infections

Rice engineers use gene editing to facilitate drug discovery based on natural fungus

New process could fast track antiviral and anticancer drug discovery

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

High concentrations of toxic pollutants were detected in stranded whales, dolphins

UArizona researcher aims to deliver statins effectively into the brain of stroke patients

Sanford Burnham Prebys receives NIH grant to identify new therapies for mental disorders

3D organoid model helps better understand how tumor grows in natural microenvironment

Sterile deep well plates

Artificial intelligence can increase effectiveness of drug repurposing for psychiatric disorders

Harbour BioMed and Viva Biotech announce strategic collaboration to promote incubation of biotech startups

First 3D multicellular brain organoid can screen drugs to control inflammation

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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