Immune System News and Research

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New insights into the pathogenic mechanisms of SLC29A3 disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

22 Aug 2023

Study shows link between regulatory T cells and anxiety, depression, Alzheimer's disease

Regulatory T cells-;work horses of the body's immune system-;may also stabilize mood, according to a study. Forkhead box P3 (Foxp3) is a transcription factor that controls the production of regulatory T cells (Tregs).

22 Aug 2023

Many older adults show interest in getting vaccinated against respiratory syncytial virus

The first Americans over age 60 just started rolling up their sleeves to get vaccinated against respiratory syncytial virus, or RSV, now that brand-new vaccines have started to arrive at pharmacies and clinics.

22 Aug 2023

Kidney–Gut axis: study shows potential link between gut dysbiosis and chronic kidney disease

Researchers reviewed published scientific work on the kidney-gut axis.

22 Aug 2023

Omicron infection may increase risk of reinfection, study finds

Researchers at McMaster University have found that rather than conferring immunity against future infections, infection during the first Omicron wave of COVID left the seniors they studied much more vulnerable to reinfection during the second Omicron wave.

21 Aug 2023

Study sheds light on how SARS-CoV-2 virus switches between replication and packaging

Immediately after the infection of a cell in the throat or lungs, the SARS-CoV-2 virus works very hard to replicate, using the human cell's metabolic pathways to produce its proteins and make sure that its genetic material (the RNA genome) is copied.

21 Aug 2023

New microneedles could monitor melanoma therapy response

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do.

21 Aug 2023

The standard of care and recent advancements in the control of skin inflammation

Researchers discuss current therapeutic interventions for atopic dermatitis in children and adolescents.

21 Aug 2023

Glycans and GBPs: How their interplay shapes immunity in infection and autoimmune diseases

Researchers discuss the regulatory roles of glycans and glycan-binding proteins in modulating immune responses.

21 Aug 2023

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Findings from a two-year study of nearly 2,400 solid organ transplant recipients, conducted by the Johns Hopkins Transplant Research Center (TRC) in collaboration with the New York University Center for Surgical and Applied Transplant Research, indicate spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus' omicron subvariant.

18 Aug 2023

Severe COVID-19 may cause long-term changes to innate immune system

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

18 Aug 2023

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells.

18 Aug 2023

Severe COVID-19 causes long-lasting changes to immune system stem cells

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body's immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators.

18 Aug 2023

New artificial DNA structures can target and destroy cancer cells

A new study highlights the potential of artificial DNA structures that, when fitted with antibodies, instruct the immune system to specifically target cancerous cells.

18 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Platelets quell the inflammation of an aging brain and body: Study finds

Platelets are behind the cognitive benefits of young blood, exercise and the longevity hormone klotho

18 Aug 2023

Immunotherapy combination extends progression-free survival in patients with melanoma

A research team co-led by UCLA investigators has shown that an immunotherapy drug combination can be an effective second-line therapy for patients with an aggressive and deadly type of melanoma that is resistant to the widely used immunotherapy drugs known as PD-1 inhibitors.

17 Aug 2023

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have been awarded a grant from the U.S. Department of Defense (DoD)'s Congressionally Directed Medical Research Program to target chemotherapy resistance in pancreatic cancer.

17 Aug 2023

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

STING gene variant linked to increased risk of severe group A strep infections

Group A streptococci are fairly common bacteria that can cause, among other things, strep throat or impetigo.

17 Aug 2023

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Immune System News and Research

New insights into the pathogenic mechanisms of SLC29A3 disorders

Study shows link between regulatory T cells and anxiety, depression, Alzheimer's disease

Many older adults show interest in getting vaccinated against respiratory syncytial virus

Kidney–Gut axis: study shows potential link between gut dysbiosis and chronic kidney disease

Omicron infection may increase risk of reinfection, study finds

Study sheds light on how SARS-CoV-2 virus switches between replication and packaging

New microneedles could monitor melanoma therapy response

The standard of care and recent advancements in the control of skin inflammation

Glycans and GBPs: How their interplay shapes immunity in infection and autoimmune diseases

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Severe COVID-19 may cause long-term changes to innate immune system

RARα receptor plays unexpected role in T cell activation

Severe COVID-19 causes long-lasting changes to immune system stem cells

New artificial DNA structures can target and destroy cancer cells

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Platelets quell the inflammation of an aging brain and body: Study finds

Immunotherapy combination extends progression-free survival in patients with melanoma

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

STING gene variant linked to increased risk of severe group A strep infections

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