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Elsevier launches open access journal

Elsevier, a world-leading provider of scientific, technical and medical information, products and solutions announces the launch of open access journal, Interdisciplinary Neurosurgery: Advanced Techniques and Case Management.

23 Dec 2013

Engineered immune cells show antitumor activity in two patients with advanced cancers

Engineered immune cells, called CARTmeso cells, designed to direct antitumor immune responses toward tumors that carry a protein called mesothelin, showed antitumor activity in two patients with advanced cancers that had not responded to prior treatments, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.

22 Dec 2013

New optical device puts the power to detect retinal disease in the palm of a hand

A new optical device puts the power to detect eye disease in the palm of a hand. The tool-about the size of a hand-held video camera-scans a patient's entire retina in seconds and could aid primary care physicians in the early detection of a host of retinal diseases including diabetic retinopathy, glaucoma and macular degeneration.

22 Dec 2013

CUMC researchers clarify three fundamental issues about Alzheimer's disease

Using high-resolution functional MRI imaging in patients with Alzheimer's disease and in mouse models of the disease, Columbia University Medical Center researchers have clarified three fundamental issues about Alzheimer's: where it starts, why it starts there, and how it spreads. In addition to advancing understanding of Alzheimer's, the findings could improve early detection of the disease, when drugs may be most effective.

22 Dec 2013

Newly-discovered selective process may explain why brain function does not deteriorate

As we grow older, our brains undergo a major reorganisation reducing the connections in the brain. Studying people up to the age of 40, scientists led by Dr Marcus Kaiser and Ms Sol Lim at Newcastle University found that while overall connections in the brain get streamlined, long-distance connections that are crucial for integrating information are preserved.

20 Dec 2013

USC's Keck Medicine becomes world's first center to implant responsive brain device to treat epilepsy

On Dec. 18, Keck Medicine of USC became the world's first medical center to implant a responsive brain device newly approved by the Food and Drug Administration to treat epilepsy, with potential to help millions of people worldwide.

20 Dec 2013

People with diabetes at risk of developing diabetic macular edema during their lifetime

Despite recent advances in prevention and treatment of most vision loss attributed to diabetes, a new study shows that fewer than half of Americans with damage to their eyes from diabetes are aware of the link between the disease and visual impairment, and only six in 10 had their eyes fully examined in the year leading up to the study.

20 Dec 2013

New MRI approach can be important tool for diagnosing, tracking MS progression

New imaging research from Western University (London, Canada) has demonstrated that a magnetic resonance imaging approach called quantitative susceptibility mapping can be an important tool for diagnosing and tracking the progression of Multiple Sclerosis and other neurological diseases.

20 Dec 2013

New research assesses nanomedicine-based approaches for treating cancer

As cancer maintains its standing as the second leading cause of death in the U.S., researchers have continued their quest for safer and more effective treatments. Among the most promising advances has been the rise of nanomedicine, the application of tiny materials and devices whose sizes are measured in the billionths of a meter to detect, diagnose and treat disease.

20 Dec 2013

Researchers receive 3 Patient-Centered Outcomes Research Institute awards from PCORI

Research teams at Group Health Research Institute have been approved for funding awards by the Patient-Centered Outcomes Research Institute (PCORI) to study opioid therapy and asthma-and to help expand a health data network that will be part of PCORnet: the National Patient-Centered National Clinical Research Network.

20 Dec 2013

Australian Therapeutic Goods Administration approves Genzyme's Lemtrada for multiple sclerosis

Genzyme, a Sanofi company, announced today that the Australian Therapeutic Goods Administration has approved Lemtrada (alemtuzumab) for the treatment of relapsing forms of multiple sclerosis for patients with active disease defined by clinical or imaging features to slow the accumulation of physical disability and reduce the frequency of clinical relapses.

19 Dec 2013

Blaze Bioscience to initiate first Phase 1 clinical study of BLZ-100 in patients with skin tumors

Blaze Bioscience, Inc. and its subsidiary, Blaze Bioscience Australia Pty Ltd, today announced the initiation of the first Phase 1 clinical study of the first Tumor Paint product candidate, BLZ-100. The study, titled "A Phase I Dose Escalation/Expansion Study of BLZ-100 Administered by Intravenous Injection in Adult Subjects with Skin Cancer," will enroll up to 30 patients with basal cell carcinoma, squamous cell carcinoma, or amelanotic melanoma.

19 Dec 2013

Royal Philips gets FDA approval for Spectral Breast Density Measurement Application

As breast density becomes a more recognized risk factor for breast cancer, Royal Philips today announced 510(k) clearance from the U.S. Food and Drug Administration for the Spectral Breast Density Measurement Application for its MicroDose SI full-field digital mammography system. The application is the first spectral Breast Density Measurement tool, meaning adipose (fat) and glandular tissue can be differentiated to accurately measure volumetric breast density.

19 Dec 2013

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Rare copy-number variants that confer a high risk for schizophrenia or autism are associated with impaired cognition in carriers without psychiatric disorders, researchers report in Nature.

19 Dec 2013

Researchers investigate several non-invasive methods for measuring intracranial pressure

Do you ever turn your world upside down by standing on your head? After a few minutes you might feel some pressure in your face and around your skull. This is because headstands invert the body's blood flow, pushing more blood toward your head.

19 Dec 2013

NUS scientists open possible new route for treatment of spinal muscular atrophy

A recent study led by scientists from the National University of Singapore (NUS) opens a possible new route for treatment of Spinal Muscular Atrophy (SMA), a devastating disease that is the most common genetic cause of infant death and also affects young adults.

18 Dec 2013

Brain's primary cortex generates efficiently compressed sensory information

Ten million bits - that's the information volume transmitted every second with every quick eye movement from the eye to the cerebrum. Researchers from the Ruhr-Universit-t Bochum (RUB) and the University of Osnabr-ck describe the way those data are processed by the primary visual cortex, the entry point for the visual information into the brain, in the journal "Cerebral Cortex".

18 Dec 2013

Studies suggest that stress-related disorders may be associated with hippocampal volume loss

Depression has been associated with reduced volume of the hippocampus in magnetic resonance imaging studies in humans. A new study just published in Biological Psychiatry now clarifies the cellular basis of these volumetric changes, which have been unclear until now.

18 Dec 2013

Navidea seeks FDA approval for marketing Lymphoseek Injection for SLN detection

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, announced today that it has submitted a Supplemental New Drug Application with the U.S. Food and Drug Administration seeking approval for the marketing and sale of Lymphoseek (technetium 99m tilmanocept) Injection for sentinel lymph node detection in patients with head and neck cancer, an indication for which Lymphoseek was also granted Fast Track designation earlier this month.

17 Dec 2013

Rich club disconnectivity may be ‘core’ schizophrenia feature

The impaired “rich club” connectivity observed in the brains of patients with schizophrenia is also present in their unaffected siblings, report researchers.

17 Dec 2013

Imaging News and Research

Elsevier launches open access journal

Engineered immune cells show antitumor activity in two patients with advanced cancers

New optical device puts the power to detect retinal disease in the palm of a hand

CUMC researchers clarify three fundamental issues about Alzheimer's disease

Newly-discovered selective process may explain why brain function does not deteriorate

USC's Keck Medicine becomes world's first center to implant responsive brain device to treat epilepsy

People with diabetes at risk of developing diabetic macular edema during their lifetime

New MRI approach can be important tool for diagnosing, tracking MS progression

New research assesses nanomedicine-based approaches for treating cancer

Researchers receive 3 Patient-Centered Outcomes Research Institute awards from PCORI

Australian Therapeutic Goods Administration approves Genzyme's Lemtrada for multiple sclerosis

Blaze Bioscience to initiate first Phase 1 clinical study of BLZ-100 in patients with skin tumors

Royal Philips gets FDA approval for Spectral Breast Density Measurement Application

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Researchers investigate several non-invasive methods for measuring intracranial pressure

NUS scientists open possible new route for treatment of spinal muscular atrophy

Brain's primary cortex generates efficiently compressed sensory information

Studies suggest that stress-related disorders may be associated with hippocampal volume loss

Navidea seeks FDA approval for marketing Lymphoseek Injection for SLN detection

Rich club disconnectivity may be ‘core’ schizophrenia feature

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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