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MDI Biological Laboratory introduces Morris Scientific Discovery Fund for eligible research programs

The MDI Biological Laboratory has announced the formation of the Morris Scientific Discovery Fund, which will provide a total of up to $250,000 per year for eligible research programs.

14 Aug 2018

New study focuses on promise of gene therapy for Amish nemaline myopathy

A new comprehensive natural history study about Amish nemaline myopathy in the Old Order Amish population focuses on the promise of gene therapy for this lethal disorder.

14 Aug 2018

University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

University Hospitals Seidman Cancer Center launched a new clinical trial for CAR-T, joining a select group of hospitals offering the therapy and a smaller group of hospitals manufacturing the CAR-T cells.

14 Aug 2018

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Nitrogen is a basic building block of all the body's proteins, RNA and DNA, so cancerous tumors are greedy for this element. Researchers at the Weizmann Institute of Science, in collaboration with colleagues from the National Cancer Institute and elsewhere, have now shown that in many cancers, the patient's nitrogen metabolism is altered, producing detectable changes in the body fluids and contributing to the emergence of new mutations in cancerous tissue.

13 Aug 2018

Researchers develop revolutionary zebrafish model to gain more insight into bone diseases

Although much scientific research has been done into the development of the skeleton, the underlying mechanisms that drive the formation and maintenance of our bones are still not very well understood, and research into the development of our bone remains of enormous importance.

13 Aug 2018

Researchers discover epigenetic mechanism underlying ischemic cardiomyopathy

Researchers at the University of Alabama at Birmingham have shed light on an epigenetic reprogramming mechanism that underlies the development of ischemic cardiomyopathy.

13 Aug 2018

Study: Patients taking OTC drugs, dietary supplements not aware of effects on lab test results

Over-the-counter drugs and dietary supplements are widely used and popular, with US households spending an average of almost USD 350 annually on OTC products. In 2006 an average of EUR 67.50 was spent per person on OTC products in Germany.

13 Aug 2018

Study may help increase effectiveness of antibiotics against drug-resistant bacteria

Bacteria-;especially Gram-negative strains-;are becoming increasingly resistant to current antibiotic drugs, and the development of new classes of antibiotics has slowed.

13 Aug 2018

New biomarker may provide clues to create diagnostic tool for hypoglycemia-associated autonomic failure

A new LSU Pennington Biomedical Research Center study reveals that a novel biomarker might give us new answers necessary to creating a diagnostic tool for hypoglycemia-associated autonomic failure.

13 Aug 2018

FDA approves first oral medication for treatment of adults with Fabry disease

The U.S. Food and Drug Administration today approved Galafold (migalastat), the first oral medication for the treatment of adults with Fabry disease.

10 Aug 2018

Researchers uncover new details in how the olfactory epithelium develops

Dogs, known for their extraordinarily keen senses of smell, can be trained to use their sensitive sniffers to find drugs, bombs, bed bugs, missing hikers and even cancer. Among dogs and other animals that rely on smell, at least one factor that may give them an advantage is a sheet of tissue in the nasal cavity.

10 Aug 2018

New laboratory-synthesized molecule appears to fight malaria effectively

A novel laboratory-synthesized molecule based in natural compounds found in marine gliding bacteria - known as marinoquinolines - is a strong candidate for the development of a new antimalarial drug.

10 Aug 2018

Supercomputer simulations reveal potential therapeutic target in HIV-1 replication

HIV-1 replicates in ninja-like ways. The virus slips through the membrane of vital white blood cells. Inside, HIV-1 copies its genes and scavenges parts to build a protective bubble for its copies.

10 Aug 2018

Researchers find potential therapeutic target for treating obesity and diabetes

A newly published study by researchers from the University of Colorado School of Medicine has identified a potential therapeutic target for treating obesity and diabetes.

10 Aug 2018

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Galectins attach to other proteins via the carbohydrates on their surfaces (sugar-binding proteins). As such they impact on a range of processes in the cell associated with a number of diseases, including heart disease and breast cancer – the most common cancer in women worldwide, with 1.7 million new cases diagnosed in 2012 alone.

10 Aug 2018

Study: Rare lymphoid cells play key role in development of inflammatory arthritis

Immunologists at Friedrich-Alexander-Universität Erlangen-Nürnberg have demonstrated that ILC2, a group of rare lymphoid cells, play a key role in the development of inflammatory arthritis.

10 Aug 2018

One-two punch of powerful antibodies may be best way to stop Ebola virus

A one-two punch of powerful antibodies may be the best way to stop Ebola virus, reports an international team of scientists in the journal Cell.

10 Aug 2018

GSS sensors provide stable CO2 control for laboratory incubator applications

Gas Sensing Solutions is helping to solve a challenge with laboratory incubator applications. Incubators are typically used to grow bacteria and micro-organisms, and to culture cells and tissues for research and clinical purposes.

10 Aug 2018

OGT announces launch of updated SureSeq Interpret NGS analysis software

Oxford Gene Technology, The Molecular Genetics Company, has announced the launch of the eagerly-anticipated update to its SureSeq Interpret software, included with purchases of SureSeq NGS panels.

From Oxford Gene Technology 10 Aug 2018

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical therapeutic, safety concerns relating to off-target effects must be minimized to mitigate risks that may arise from the unintended action of this system at sites similar, but not identical, to the desired gene target site.

From Integrated DNA Technologies 10 Aug 2018

Laboratory News and Research

MDI Biological Laboratory introduces Morris Scientific Discovery Fund for eligible research programs

New study focuses on promise of gene therapy for Amish nemaline myopathy

University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Researchers develop revolutionary zebrafish model to gain more insight into bone diseases

Researchers discover epigenetic mechanism underlying ischemic cardiomyopathy

Study: Patients taking OTC drugs, dietary supplements not aware of effects on lab test results

Study may help increase effectiveness of antibiotics against drug-resistant bacteria

New biomarker may provide clues to create diagnostic tool for hypoglycemia-associated autonomic failure

FDA approves first oral medication for treatment of adults with Fabry disease

Researchers uncover new details in how the olfactory epithelium develops

New laboratory-synthesized molecule appears to fight malaria effectively

Supercomputer simulations reveal potential therapeutic target in HIV-1 replication

Researchers find potential therapeutic target for treating obesity and diabetes

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Study: Rare lymphoid cells play key role in development of inflammatory arthritis

One-two punch of powerful antibodies may be best way to stop Ebola virus

GSS sensors provide stable CO2 control for laboratory incubator applications

OGT announces launch of updated SureSeq Interpret NGS analysis software

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

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