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Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

A new study from researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.

11 Dec 2023

New organoid model could revolutionize neuroendocrine tumor research

The Organoid Group (Hubrecht Institute) and the Rare Cancers Genomics Team (IARC/WHO) found a way to grow samples of different types of neuroendocrine tumors (NETs) in the lab.

11 Dec 2023

DeepMirror launches early access programme for its intuitive molecular drug design software

Innovative product enables medicinal chemists to access and integrate AI to boost productivity and creativity, to accelerate therapeutic drug discovery.

From DeepMirror 11 Dec 2023

‘Naughty but nice’ Christmas foods can help achieve a better balance of cholesterol, expert says

Finally, there’s good news about many of our favorite Christmas foods. A turkey meal with all – well, most – of the trimmings and a traditional dessert can lower your LDL ‘bad’ cholesterol levels and improve your ratio of HDL good cholesterol, reveals a leading testing expert.

11 Dec 2023

Highly bioavailable, pure form of astaxanthin safely fights inflammaging to improve lifespan

AX3 Life announced breakthrough life extension findings related to its longevity supplement, AX3® Bio-Pure Astaxanthin.

11 Dec 2023

COVID-19 significantly raises risk of severe complications in pregnant women

Study found that pregnant mothers with COVID-19 face a significantly higher risk of severe maternal morbidity (SMM), including adult respiratory distress syndrome and acute renal failure, emphasizing the urgent need for their early diagnosis and treatment.

10 Dec 2023

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Using machine learning, researchers successfully distinguished factors of healthy aging from chronic disease risks by analyzing health data across various ages, finding key markers like neutrophil counts and alkaline phosphatase levels as early indicators of healthy aging.

10 Dec 2023

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Patients with low-risk ductal carcinoma in situ (DCIS) who skipped adjuvant radiotherapy after breast-conserving surgery had comparable five-year outcomes to those with high-risk DCIS who received adjuvant radiotherapy, according to results from the E4112 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Expanding the toolbox for drug design: New enzymes for tailoring molecules

Simon Schröder has worked out how enzymes can be used to more easily form the desired bond between two nitrogen atoms.

8 Dec 2023

New VR goggles for mice provide more immersive experiences for lab research

Northwestern University researchers have developed new virtual reality (VR) goggles for mice.

8 Dec 2023

Cryo-EM reveals TAF15 as potential treatment target for frontotemporal dementia

An international team of researchers including experts at the Indiana University School of Medicine has identified a protein found in the brains of people with frontotemporal dementia (FTD), discovering a new target for potential treatments for the disease.

7 Dec 2023

Flaxseed lignans found to influence gut microbiome and breast cancer risk

A new study demonstrates that the human gut microbiome may be a factor in breast health. Lifestyle and diet have long been known to affect human health.

7 Dec 2023

Study reveals need for improved infection prevention for high-risk healthcare personnel

A new study published today in the American Journal of Infection Control (AJIC), based on a survey of healthcare professionals conducted during the height of the COVID-19 pandemic, suggests that new efforts may be needed to strengthen infection prevention precautions and protect staff members at the highest risk of exposure to dangerous pathogens.

7 Dec 2023

Birth control pills may alter stress response, increase inflammation risk, study suggests

A new UCLA Health study is shedding light on how using hormonal contraceptive pills may affect women's responses to stress and their risk for inflammation-related illnesses.

7 Dec 2023

New early phase study evaluates “on-demand” HIV prevention method for women

A fast-dissolving vaginal insert that women would use at or around the time of sex as an "on-demand" HIV prevention method is being evaluated in a new early phase study being conducted by MATRIX, a United States Agency for International Development (USAID)-funded project focused on the early research and development of innovative HIV prevention products for women.

7 Dec 2023

Breakthrough discovery paves the way for new methods to detect and treat leukemia

Researchers led by François Fuks - Laboratory of Cancer Epigenetics, ULB Faculty of Medicine, ULB Cancer Research Center and Jules Bordet Institute, H.U.B. - have made a major breakthrough in the understanding and treatment of leukemia.

7 Dec 2023

Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.

7 Dec 2023

BICO company Biosero has signed an agreement to develop laboratory automation solutions to a value of 28 MUSD

Biosero, a BICO company and developer of laboratory automation solutions to orchestrate scientific discoveries, has signed an agreement with a global life science company for a total value of 28 MUSD to design and build an automated R&D, hardware and software platform which consists of 5 sub-projects.

From Biosero Inc. 7 Dec 2023

Researchers receive $2 million NSF grant to continue fight against airborne pathogens

Bahareh Behkam and collaborators have received a $2 million grant from the National Science Foundation (NSF) to continue their fight against airborne pathogens

6 Dec 2023

Scientists uncover key protein aggregation in frontotemporal dementia

Most neurodegenerative diseases, including dementias, involve proteins aggregating into filaments called amyloids.

6 Dec 2023

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Laboratory News and Research

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

New organoid model could revolutionize neuroendocrine tumor research

DeepMirror launches early access programme for its intuitive molecular drug design software

‘Naughty but nice’ Christmas foods can help achieve a better balance of cholesterol, expert says

Highly bioavailable, pure form of astaxanthin safely fights inflammaging to improve lifespan

COVID-19 significantly raises risk of severe complications in pregnant women

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Expanding the toolbox for drug design: New enzymes for tailoring molecules

New VR goggles for mice provide more immersive experiences for lab research

Cryo-EM reveals TAF15 as potential treatment target for frontotemporal dementia

Flaxseed lignans found to influence gut microbiome and breast cancer risk

Study reveals need for improved infection prevention for high-risk healthcare personnel

Birth control pills may alter stress response, increase inflammation risk, study suggests

New early phase study evaluates “on-demand” HIV prevention method for women

Breakthrough discovery paves the way for new methods to detect and treat leukemia

Promising candidate medication for preventing and reversing fentanyl-induced overdose

BICO company Biosero has signed an agreement to develop laboratory automation solutions to a value of 28 MUSD

Researchers receive $2 million NSF grant to continue fight against airborne pathogens

Scientists uncover key protein aggregation in frontotemporal dementia

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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