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Women and cancer today

Experts have warned that women who have their breasts removed out of fear of a high hereditary risk of breast cancer may be doing so needlessly. Genetic tests like for the BRCA mutations have predicted a high risk of getting breast cancer in women with many breast cancer sufferers among their first degree relatives. Earlier studies suggest the risk of the mutation to predict the cancer 87% of the time. Now experts want that this is an overestimate.

11 Nov 2010

Dead litigant’s family bullied by tobacco company

In 2002 Jamie McCabe’s mother Rolah won a landmark legal battle against British American Tobacco and alleges that the family is still being harassed by the tobacco giant. Ms McCabe became the first Australian to successfully sue a tobacco company. She won $700,000 in compensation after Justice Geoffrey Eames, in the Victorian Supreme Court, found the tobacco company had destroyed potentially relevant documents about the damaging effects of smoking.

11 Nov 2010

Aradigm reports $1.3M net income for third quarter 2010 vs. $3.0M net loss for third quarter 2009

Aradigm Corporation today announced financial results for the third quarter and nine months ended September 30, 2010.

11 Nov 2010

Hospital for Special Surgery presents advantages of specialized disease center for comprehensive lupus care

The benefits of collaborative, multidisciplinary care of patients with complex autoimmune diseases like lupus and multiple sclerosis are just beginning to be appreciated by physicians. Hospital for Special Surgery in New York will present evidence of the advantages of such a specialized disease center dedicated to comprehensive lupus care at the 74th Annual Meeting of the American College of Rheumatology in Atlanta.

11 Nov 2010

Number of smokers quitting has fallen since recession hit the UK economy

Since the recession began the number of smokers quitting has fallen according to new research being presented at the NCRI Cancer Conference in Liverpool today.

11 Nov 2010

Pharmaxis to present ARIDOL Bronchial Challenge Test Kit at 2010 ACAAI

Pharmaxis, a global specialty pharmaceutical company focused on therapeutic products for respiratory and immune disorders, will present ARIDOL™ (mannitol inhalation powder) Bronchial Challenge Test Kit, at the 2010 Annual Meeting of the American College of Allergy, Asthma and Immunology (ACAAI), November 11-16 in Phoenix, AZ.

11 Nov 2010

University at Buffalo smoking cessation researchers applaud federal plans on new cigarette labeling

University at Buffalo smoking cessation researchers today applauded federal plans to require cigarette packs and ads to carry bigger, much more prominent and graphic health warnings, including images of the destruction to the lungs caused by tobacco, which must cover half of a cigarette pack. In announcing the initiative, the Health and Human Services Department called the new warnings "the most significant change in more than 25 years" in cigarette packages and advertising.

11 Nov 2010

Marker for aggressive form of idiopathic pulmonary fibrosis discovered

A diagnosis of idiopathic pulmonary fibrosis is not much better than a death sentence, given a survival rate averaging 4 to 6 years as the disease robs its victim of the ability to breathe.

11 Nov 2010

USPTO issues Notice of Allowance to Asuragen’s mir-205 for lung cancer diagnosis

Asuragen, Inc., a leader in the development of molecular diagnostics, announced today that it had received a Notice of Allowance from the United States Patent and Trademark Office for claims related to the use of mir-205 as a diagnostic in lung cancer.

11 Nov 2010

Cyclacel announces publication of sapacitabine in British Journal of Cancer

Cyclacel Pharmaceuticals, Inc., a biopharmaceutical company developing oral therapies that target the various phases of cell cycle control for the treatment of cancer and other serious diseases, announced today publication of data demonstrating that its sapacitabine oral nucleoside analog works synergistically with histone deacetylase (HDAC) inhibitors to induce significant reductions in tumor cell growth in both in vitro and in vivo preclinical models.

11 Nov 2010

Dana-Farber lends iPads to cancer patients to help them pass the time in clinic

Andrea Casella comes to Dana-Farber Cancer Institute every week for chemotherapy to treat her lung cancer. It's a full day. Recognizing that patients can spend hours in the clinic for treatment and tests, Dana-Farber has started lending iPads to patients like Casella to help them pass the time.

11 Nov 2010

Childhood asthma risk linked with prenatal paracetamol exposure depends on antioxidant genes in mother

Evidence suggesting that the risk of childhood asthma associated with prenatal paracetamol exposure may depend on antioxidant genes in the mother has been found by a team of UK scientists. The results of their study - which strengthens the argument for a causal link between paracetamol exposure in early life and later childhood asthma - are published online (10 November) in the Journal of Allergy and Clinical Immunology.

11 Nov 2010

Legacy applauds HHS and FDA for new tobacco control strategic action plan

Legacy applauds HHS Secretary Kathleen Sebelius and the leadership at the U.S. Department of Health and Human Services (HHS) and the U.S. Food and Drug Administration (FDA) for its bold new effort announced today to dramatically reduce the number of American lives lost annually to tobacco-related disease. Still the number one preventable cause of death, tobacco continues to claim more than 400,000 lives each year in the United States.

11 Nov 2010

Lung cancer in smokers versus non-smokers shows different genetic mutations

A group of scientists at B.C. Cancer Agency have found that lung cancers in smokers have different genetic mutations and look different than lung cancer in non-smokers. According to senior scientist at the BC Cancer Agency Research Centre Wan Lam, this finding is significant because it means that from now on, research, treatments and diagnostics should be tailored to the distinct genetic variations in the different lung cancers instead of expecting that a one-size fits all approach will work. He said, “At the current time, treatment does not distinguish between these different types. The subtypes are all grouped together. But with this work, we are beginning to tease out the subtypes.” The study was presented Tuesday at a conference in Philadelphia of the American Association of Cancer Research.

10 Nov 2010

China Medical Technologies' EGFR PCR Assay for lung cancer targeted drugs receives Chinese SFDA approval

China Medical Technologies, Inc., a leading China-based advanced in-vitro diagnostic ("IVD") company, today announced that it has received approval for its real-time PCR-based Epidermal Growth Factor Receptor Assay (the "EGFR PCR Assay") for the use of lung cancer targeted drugs from the State Food and Drug Administration of China (the "SFDA").

10 Nov 2010

Omeros identifies orphan GPCR compound that potentiates tumor-killing activity of doxorubicin

Omeros Corporation, a biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system, today announced that a compound identified by the Company as an antagonist of GPR87, an orphan GPCR recently unlocked for drug development by Omeros and linked to squamous cell carcinoma, potentiates the tumor-killing activity of doxorubicin (Adriamycin), a widely used chemotherapeutic agent.

10 Nov 2010

Study finds different DNA alterations in tumor genomes of smokers and never-smokers

Lung tumors in those who smoke and those who never smoked have different DNA alterations in the tumor genomes, according to results of a pilot study presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia.

10 Nov 2010

Low levels of growth hormone may contribute to growth defects in cystic fibrosis

A new study using a pig model of cystic fibrosis (CF) suggests that low levels of a growth promoting hormone at or before birth may contribute to growth defects in patients with CF.

10 Nov 2010

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia.

10 Nov 2010

NHLBI launches new campaign to highlight common COPD symptoms

The number of Americans who report being aware of chronic obstructive pulmonary disease, or COPD, increased by 4 percentage points between 2008 and 2010, but many people at risk are still unaware of the disease, according to mailed survey results released today by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.

10 Nov 2010

Lungs News and Research

Women and cancer today

Dead litigant’s family bullied by tobacco company

Aradigm reports $1.3M net income for third quarter 2010 vs. $3.0M net loss for third quarter 2009

Hospital for Special Surgery presents advantages of specialized disease center for comprehensive lupus care

Number of smokers quitting has fallen since recession hit the UK economy

Pharmaxis to present ARIDOL Bronchial Challenge Test Kit at 2010 ACAAI

University at Buffalo smoking cessation researchers applaud federal plans on new cigarette labeling

Marker for aggressive form of idiopathic pulmonary fibrosis discovered

USPTO issues Notice of Allowance to Asuragen’s mir-205 for lung cancer diagnosis

Cyclacel announces publication of sapacitabine in British Journal of Cancer

Dana-Farber lends iPads to cancer patients to help them pass the time in clinic

Childhood asthma risk linked with prenatal paracetamol exposure depends on antioxidant genes in mother

Legacy applauds HHS and FDA for new tobacco control strategic action plan

Lung cancer in smokers versus non-smokers shows different genetic mutations

China Medical Technologies' EGFR PCR Assay for lung cancer targeted drugs receives Chinese SFDA approval

Omeros identifies orphan GPCR compound that potentiates tumor-killing activity of doxorubicin

Study finds different DNA alterations in tumor genomes of smokers and never-smokers

Low levels of growth hormone may contribute to growth defects in cystic fibrosis

Long-term use of statins unlikely to substantially increase overall cancer risk: Study

NHLBI launches new campaign to highlight common COPD symptoms

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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