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Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

New findings reveal the long-standing underrepresentation of women in cardiology leadership roles

In a trio of studies analyzing trends in cardiology research funding, clinical trials and leadership, Johns Hopkins Medicine researchers say some progress has been made in the gender gap that has long favored men, but inequalities persist and are likely linked to ongoing disparities in outcomes for women with heart disease.

20 Apr 2022

Five different diseases attack language areas in the brain that cause primary progressive aphasia

There are five different diseases that attack the language areas in the left hemisphere of the brain that slowly cause progressive impairments of language known as primary progressive aphasia (PPA), reports a new Northwestern Medicine study.

20 Apr 2022

Disasters can disrupt access to medications for opioid use disorder in vulnerable communities

The COVID-19 pandemic has spiked the overdose death rate from opioid use. For people who rely on medications (buprenorphine, methadone, and extended-release naltrexone) to treat opioid use disorders, the pandemic and such natural disasters as tornados, hurricanes, and wildfires can disrupt access to medications.

20 Apr 2022

New point-of-care COVID-19 test can differentiate alpha variant from earlier SARS-CoV-2 strains

A point-of-care COVID-19 test developed by researchers at the University of Illinois Urbana-Champaign can now detect and differentiate the alpha variant of the SARS-CoV-2 virus from earlier strains in saliva samples.

20 Apr 2022

Researchers uncover a new protective mechanism against non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

20 Apr 2022

People with severe mental illness have increased risk of cardiovascular-related mortality

Compared to the general population, people with severe mental illness, including schizophrenia, have higher levels of cardiovascular-related mortality, and that association has become stronger over recent decades, according to a new study publishing April 19th in PLOS Medicine by Amanda Lambert of the University of Birmingham, UK, and colleagues.

19 Apr 2022

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Alzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities.

19 Apr 2022

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

A little-studied enzyme has been found in high levels in healthy neurons, levels that scientists say decline with age and more dramatically with Alzheimer's, making adjusting the enzyme's level a potential treatment for both.

19 Apr 2022

UCLA research finds "Long COVID" in 30% of people treated for COVID-19

New UCLA research finds that 30% of people treated for COVID-19 developed Post Acute Sequelae of COVID-19 (PASC), most commonly known as "Long COVID."

19 Apr 2022

Study finds similar outcomes for virtual and hybrid cardiac rehabilitation as in-person treatment

Cardiac rehabilitation (CR) reduces hospitalization and mortality and improves quality of life for patients with cardiovascular disease.

19 Apr 2022

Lifelong excess weight almost doubles the risk of developing womb cancer, shows study

New research shows that lifelong excess weight almost doubles a woman's risk of developing womb cancer, according to a Cancer Research UK-funded study published today in BMC Medicine.

19 Apr 2022

CHEST and Three Lakes Foundation collaborate to reduce delays in diagnosing Interstitial Lung Diseases

Three Lakes Foundation and the American College of Chest Physicians recently announced their collaboration on a multiphase educational initiative aiming to reduce the time it takes to diagnose patients with Interstitial Lung Diseases (ILD).

19 Apr 2022

Study finds higher risk of dementia among patients hospitalized with COVID-19 pneumonia

A new study from the from the University of Missouri School of Medicine and MU Health Care shows patients hospitalized with COVID-19 pneumonia have a higher risk of developing dementia than those with other types of pneumonia.

19 Apr 2022

Researchers reveal possible way to treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

19 Apr 2022

WEB device found to be safe and effective in treating sidewall brain aneurysms

A novel mesh plug that has been traditionally used to treat brain aneurysms occurring where the blood vessels branch out was found to be equally effective in treating aneurysms on the side of the vessel, according to a study in the journal Radiology.

19 Apr 2022

Mount Sinai wins $500,000 grant to support continued innovation in pancreatic cancer treatment

The Canopy Cancer Collective, a national nonprofit organization that strives to fuel better treatments and outcomes for pancreatic cancer patients, has awarded The Tisch Cancer Institute at Mount Sinai a $500,000 grant to support continued innovation in its multidisciplinary treatment of pancreatic cancer.

19 Apr 2022

Wearables can identify changes in physiological systems during COVID-19 disease progression

If you become ill with COVID-19, your smartwatch can track the progression of your symptoms, and could even show how sick you become.

19 Apr 2022

Research sheds new light on how the body's immune system deals with malaria

By analyzing samples from patients who have been treated for malaria in Sweden, researchers at Karolinska Institutet can now describe how the immune system acts to protect the body after a malaria infection.

19 Apr 2022

Medicine News and Research

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

New findings reveal the long-standing underrepresentation of women in cardiology leadership roles

Five different diseases attack language areas in the brain that cause primary progressive aphasia

Disasters can disrupt access to medications for opioid use disorder in vulnerable communities

New point-of-care COVID-19 test can differentiate alpha variant from earlier SARS-CoV-2 strains

Researchers uncover a new protective mechanism against non-alcoholic fatty liver disease

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

People with severe mental illness have increased risk of cardiovascular-related mortality

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

UCLA research finds "Long COVID" in 30% of people treated for COVID-19

Study finds similar outcomes for virtual and hybrid cardiac rehabilitation as in-person treatment

Lifelong excess weight almost doubles the risk of developing womb cancer, shows study

CHEST and Three Lakes Foundation collaborate to reduce delays in diagnosing Interstitial Lung Diseases

Study finds higher risk of dementia among patients hospitalized with COVID-19 pneumonia

Researchers reveal possible way to treat newborns with rare genetic lung condition

WEB device found to be safe and effective in treating sidewall brain aneurysms

Mount Sinai wins $500,000 grant to support continued innovation in pancreatic cancer treatment

Wearables can identify changes in physiological systems during COVID-19 disease progression

Research sheds new light on how the body's immune system deals with malaria

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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