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Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications.

19 Apr 2022

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

19 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

NTNU researcher explores how kids are affected by coronavirus, RS virus and rhinovirus

For two years now, the novel coronavirus SARS-CoV-2 has ravaged populations the world over. Some researchers believe that the virus will mutate toward less harmless variants.

19 Apr 2022

Discovery can lead to new antiviral treatments against Crimean-Congo hemorrhagic fever

Researchers at Karolinska Institutet in Sweden have identified key signaling pathways that when blocked by existing drug candidates limit reproduction of the Crimean-Congo hemorrhagic fever (CCHF) virus.

19 Apr 2022

Why cheap, older drugs that might treat covid never get out of the lab

In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the covid ward at Yale New Haven Hospital, joining an army of health care workers who struggled to treat the deadly viral disease.

19 Apr 2022

As eating disorders spike during pandemic, rural treatment options lag

Erin Reynolds had battled bulimia since childhood, but the weeks before she entered treatment were among her worst. At 22, she was preparing to leave her home in Helena, Montana, for an inpatient program in New Jersey with round-the-clock medical care.

19 Apr 2022

COVID-19 vaccine reduced the risk of hospitalizations in children during the Omicron period

Results of a new multicenter study published in the New England Journal of Medicine found that vaccination with a primary series of the Pfizer-BioNTech mRNA COVID-19 vaccine reduced the risk of COVID-19-associated hospitalizations in children ages 5–11 years by two-thirds during the Omicron period.

19 Apr 2022

Injectable hybrid inorganic nanoscaffold-templated stem cell assembly for cartilage repair

This study led by Prof. Qiuyu Zhang (Northwestern Polytechnical University), Prof. Ki-Bum Lee (Rutgers University), and Prof. Liang Kong (School of Stomatology, The Fourth Military Medical University).

19 Apr 2022

UK experts share their work in the field of opioid use disorder research at 2022 Rx Summit

University of Kentucky experts on the front lines of the nation's opioid and addiction crises will share their work in the field of opioid use disorder research, treatment and prevention this week at the 2022 Rx Drug Abuse & Heroin Summit in Atlanta April 18-22.

19 Apr 2022

New microbiopsy device could change the way skin cancers are diagnosed

A skin microbiopsy device developed by researchers at The University of Queensland, that takes tissue samples smaller than 0.5mm in diameter, could change the way skin cancers and other skin conditions are diagnosed and monitored.

19 Apr 2022

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly.

18 Apr 2022

Better understanding of hydrocephalus could lead to improved treatments

Hydrocephalus, or "water on the brain," occurs when the cerebral ventricles-; four interconnected cavities of the brain that are filled with cerebrospinal fluid-; become enlarged, but its cause is unknown in many cases.

18 Apr 2022

Triage team members experience moral distress during a simulated crisis-care event

The COVID-19 pandemic has led healthcare organizations to draft plans for critical patient care in the event of shortages of resources such as ventilators.

18 Apr 2022

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A.

18 Apr 2022

Researchers develop and validate polygenic risk scores for six common diseases

A person's risk of developing diseases such as type 2 diabetes or breast cancer may be influenced by thousands of genetic differences.

18 Apr 2022

New report highlights how the devastating combination of autism, poverty and race impacts health

The Autism Intervention Research Network on Physical Health (AIR-P), a multi-site collaboration housed within UCLA Health's Department of Medicine, has released a new report that uses national data to highlight the intersection of autism, poverty and race/ethnicity and their compounding impact on health and health care.

18 Apr 2022

Research shows tsRNA as a promising biomarker for early diagnosis of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most primary liver cancer. It is one of the most common and mortal cancer worldwide, especially in East Asia. Advanced HCC patients expect a significantly low 5-year survival rate as well as poor prognosis.

18 Apr 2022

4th dose of mRNA Covid-19 vaccine significantly increases protection in age 60+

Researchers compare the efficacy of the SARS-CoV-2 Pfizer-BioNTech BNT162b2 third- and fourth-dose vaccinations in Israel.

18 Apr 2022

Racial disparities after hip and knee replacement reduced by a "bundled care" Medicare program

A "bundled care" Medicare program to improve care for patients undergoing hip or knee replacement surgery has led to reductions in some outcome disparities for Black compared with White patients, suggests a study in The Journal of Bone & Joint Surgery.

18 Apr 2022

Medicine News and Research

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Scientists precisely define the ‘identity card’ of pancreatic endocrine cells

Using customized 'mini-antibodies' to mitigate chronic inflammation

NTNU researcher explores how kids are affected by coronavirus, RS virus and rhinovirus

Discovery can lead to new antiviral treatments against Crimean-Congo hemorrhagic fever

Why cheap, older drugs that might treat covid never get out of the lab

As eating disorders spike during pandemic, rural treatment options lag

COVID-19 vaccine reduced the risk of hospitalizations in children during the Omicron period

Injectable hybrid inorganic nanoscaffold-templated stem cell assembly for cartilage repair

UK experts share their work in the field of opioid use disorder research at 2022 Rx Summit

New microbiopsy device could change the way skin cancers are diagnosed

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Better understanding of hydrocephalus could lead to improved treatments

Triage team members experience moral distress during a simulated crisis-care event

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

Researchers develop and validate polygenic risk scores for six common diseases

New report highlights how the devastating combination of autism, poverty and race impacts health

Research shows tsRNA as a promising biomarker for early diagnosis of hepatocellular carcinoma

4th dose of mRNA Covid-19 vaccine significantly increases protection in age 60+

Racial disparities after hip and knee replacement reduced by a "bundled care" Medicare program

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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