Immune System News and Research

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Surprising new role for a key immune regulator revealed

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

3 Aug 2023

CAR-T immune therapies could be effective against solid tumors

CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests.

3 Aug 2023

Children raised in rural areas have better regulated immune systems

Children raised in rural environments who spend a lot of time outdoors with some exposure to animals grow to have better regulated immune systems than children living in urban environments, a new study has found.

3 Aug 2023

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

A University of Ottawa-led research team has published rigorous new research that advances a quest to understand a puzzling – and heartbreaking – ultra-rare disease that's found almost exclusively in boys.

3 Aug 2023

NIH awards $18 million to develop novel chikungunya vaccine

The Access to Advanced Health Institute (AAHI) announced today that it has received an $18 million award from the National Institutes of Health (NIH) to develop a temperature stable, single-dose vaccine candidate for the chikungunya virus.

3 Aug 2023

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

Researchers evaluated the physiological roles of an antimicrobial peptide.

3 Aug 2023

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Researchers discuss the mechanisms of triptans for the treatment of spontaneous migraine attacks by using transcriptomics and metabolomics.

3 Aug 2023

Genome-wide study finds link between CHD1L gene and HIV control

"We searched for human genetic variation that associates with spontaneous control of HIV and identified a novel region in the genome that is only variable in populations of African ancestries," says Professor Jacques Fellay at EPFL's School of Life Sciences.

2 Aug 2023

Overcoming the oxygen sensitivity of anti-inflammatory gut bacterium

One of the beneficial gut bacteria residing in the human gut, which normally cannot survive in an environment with oxygen, can now be made oxygen-tolerant.

2 Aug 2023

Novel molecules inspired by the immune system inactivate several viruses

Antiviral therapies are notoriously difficult to develop, as viruses can quickly mutate to become resistant to drugs. But what if a new generation of antivirals ignores the fast-mutating proteins on the surface of viruses and instead disrupts their protective layers?

2 Aug 2023

Peptoid antiviral therapy inactivates three viruses in lab tests

Just as bacteria can develop antibiotic resistance, viruses can also evade drug treatments. Developing therapies against these microbes is difficult because viruses often mutate or hide themselves within cells.

2 Aug 2023

Study offers deeper understanding of regulatory T cells yielding therapeutic benefits

Decades of research have left knowledge gaps about cells that regulate the immune system: Purdue and NIH.

1 Aug 2023

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham health system, officially opened the Legorreta Center for Clinical Transplant Tolerance, the first-of-its kind center in the world dedicated to preventing organ rejection after transplant surgery without the use of lifelong immunosuppressive medications.

1 Aug 2023

Lead exposure in early life may increase risk of adult criminality

An evaluation of 17 previously published studies suggests that exposure to lead in the womb or in childhood is associated with an increased risk of engaging in criminal behavior in adulthood-;but more evidence is needed to strengthen understanding.

1 Aug 2023

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

1 Aug 2023

Insights into the relationship between COVID-19 and mental health

Researchers investigated the causal consequences and genetic mechanisms that link the results of SARS-CoV-2 to anxiety disorders.

1 Aug 2023

What is the relationship between intestinal stem cells and the gut microbiota in regenerative medicine?

Researchers explored the relationship between intestinal stem cells (ISCs) and the gut microbiota and its role in maintaining intestinal health.

1 Aug 2023

Monoclonal antibody shows promise in slowing progression of ALS

New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.

31 Jul 2023

NIH launches and opens enrollment for phase 2 clinical trials to evaluate long COVID treatments

Today, the National Institutes of Health launched and is opening enrollment for phase 2 clinical trials that will evaluate at least four potential treatments for long COVID, with additional clinical trials to test at least seven more treatments expected in the coming months.

31 Jul 2023

Newly identified protein plays a key role in the action of emerging anticancer therapies

Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.

31 Jul 2023

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Immune System News and Research

Surprising new role for a key immune regulator revealed

CAR-T immune therapies could be effective against solid tumors

Children raised in rural areas have better regulated immune systems

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

NIH awards $18 million to develop novel chikungunya vaccine

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Genome-wide study finds link between CHD1L gene and HIV control

Overcoming the oxygen sensitivity of anti-inflammatory gut bacterium

Novel molecules inspired by the immune system inactivate several viruses

Peptoid antiviral therapy inactivates three viruses in lab tests

Study offers deeper understanding of regulatory T cells yielding therapeutic benefits

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Lead exposure in early life may increase risk of adult criminality

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Insights into the relationship between COVID-19 and mental health

What is the relationship between intestinal stem cells and the gut microbiota in regenerative medicine?

Monoclonal antibody shows promise in slowing progression of ALS

NIH launches and opens enrollment for phase 2 clinical trials to evaluate long COVID treatments

Newly identified protein plays a key role in the action of emerging anticancer therapies

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