Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Research shows prevalence, health-care utilization, and costs of alcohol-related cirrhosis

More than one-third of cirrhosis cases are related to alcohol, a seven-year national study of more than 100 million privately insured people has found.

4 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

Scientists discover mechanism behind unusual form of tissue regeneration in the liver

By studying a rare liver disease called Alagille syndrome, scientists from Cincinnati Children's and the University of California San Francisco (UCSF) have discovered the mechanism behind an unusual form of tissue regeneration that may someday reduce the need for expensive and difficult-to-obtain organ transplants.

3 May 2018

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Due to the opioid epidemic, hepatitis C virus is increasing among pregnant women, resulting in a greater risk of perinatal transmission and HCV infection among children.

2 May 2018

Study shows effectiveness of novel risk tool to predict readmission rates after TAVR

A new study looked at the effectiveness of novel risk tool to predict 30-day readmission rates in patients undergoing transcatheter aortic valve replacement.

27 Apr 2018

Study finds myeloma precursor disease in 9/11 firefighters

A study in today's issue of JAMA Oncology reports that New York City firefighters exposed to the 9/11 World Trade Center disaster site face an increased risk for developing myeloma precursor disease (MGUS), which can lead to the blood cancer multiple myeloma.

26 Apr 2018

Girls with type 2 diabetes have high frequency of menstrual irregularities

Girls diagnosed with type 2 diabetes have a high frequency of menstrual irregularities, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

25 Apr 2018

Study explains why intense exercise curbs appetite

Ever wonder why intense exercise temporarily curbs your appetite? In research described in today's issue of PLOS Biology, Albert Einstein College of Medicine researchers reveal that the answer is all in your head-;more specifically, your arcuate nucleus.

25 Apr 2018

Preantral zinc deficiency may affect fertility months

An estimated 10 percent of couples in the U.S. struggle with infertility. While a variety of factors can make it difficult for some people to get pregnant, ovulation disorders are a leading cause of female infertility.

24 Apr 2018

Probiotics can improve liver health, shows study

Increased awareness of the importance of the microbes that live in our gut has spurred a great deal of research on the microbiome and fueled a booming probiotics industry. A new study suggests probiotics can improve not only the health of our gut but liver health, as well.

23 Apr 2018

New studies related to causes of liver degradation and possible treatments

A treatment gap remains for many conditions involving damage to the liver, the body's main organ for removing toxins, among other functions. The Experimental Biology 2018 meeting (EB 2018) will feature important research announcements related to the causes of liver degradation and possible treatments.

23 Apr 2018

SLU professor discovers new biomarkers for chlorine gas exposure

As experts sort through questions around recent chemical attacks in Syria, future answers to quickly testing and treating those who may have been exposed to chlorine gas may lie in chlorinated lipids, says a Saint Louis University professor.

19 Apr 2018

Targeting opioid receptor offers relief for chronic itching

A common side effect of opioids is intense itching -- a problem for some patients who need the drugs for pain relief and for others fighting addiction.

17 Apr 2018

Single FMT enema produces sustained and significant improvements in cognitive function

A single treatment using an optimized, targeted form of faecal microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long-term follow-up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short-term study.

16 Apr 2018

Study shows potential of web-based intervention to achieve weight loss in patients with NAFLD

Patients with non-alcoholic fatty liver disease who participated in a web-based lifestyle modification intervention achieved similar levels of weight loss and more rapid normalization of their liver enzymes than patients who participated in an intensive, group-based program.

13 Apr 2018

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress™ 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list in the USA were more than 50% less likely to receive a transplant in 2014-2016 than they were in 2005-2007.

13 Apr 2018

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

A worldwide study initiated to investigate the epidemiology and outcomes of bacterial infections in hospitalized patients with liver cirrhosis has reported a prevalence of multi-drug-resistant bacteria of 34% and significant regional differences in the risk of developing a multi-drug-resistant infection.

13 Apr 2018

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Researchers at the University of Sydney have established a method to identify individual nanoparticles released by human cells, opening the way for them to become diagnostic tools in the early-detection of cancers, dementia and kidney disease.

13 Apr 2018

Liver Disease News and Research

Further Reading

Research shows prevalence, health-care utilization, and costs of alcohol-related cirrhosis

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

Scientists discover mechanism behind unusual form of tissue regeneration in the liver

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Study shows effectiveness of novel risk tool to predict readmission rates after TAVR

Study finds myeloma precursor disease in 9/11 firefighters

Girls with type 2 diabetes have high frequency of menstrual irregularities

Study explains why intense exercise curbs appetite

Preantral zinc deficiency may affect fertility months

Probiotics can improve liver health, shows study

New studies related to causes of liver degradation and possible treatments

SLU professor discovers new biomarkers for chlorine gas exposure

Targeting opioid receptor offers relief for chronic itching

Single FMT enema produces sustained and significant improvements in cognitive function

Study shows potential of web-based intervention to achieve weight loss in patients with NAFLD

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

Researchers unlock new way to use cell's nanostructures as disease biomarkers

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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